Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development.
暂无分享,去创建一个
R Kucherlapati | R Smits | R Fodde | R. Kucherlapati | R. Fodde | R. White | R. Smits | W. Edelmann | K. Neufeld | Raymond White | M. Kielman | C. Breukel | P. Khan | W. Edelmann | W Edelmann | C Breukel | P M Khan | J. Van Dijk | C Zurcher | S Jagmohan-Changur | M F Kielman | K Neufeld | N Hofland | J van Dijk | R White | J. E. Dijk | C. Zurcher | N. Hofland | S. Jagmohan‐Changur
[1] B. Mollet,et al. A Functional Interaction , 2001 .
[2] D. Pellman,et al. The adenomatous polyposis coli-binding protein EB1 is associated with cytoplasmic and spindle microtubules. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[3] P. Stagnaro,et al. Chain‐terminating mutations in the APC gene lead to alterations in APC RNA and protein concentration , 1998, Genes, chromosomes & cancer.
[4] J. Cooper,et al. A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein , 1998, Nature.
[5] L. Donahue,et al. A new spontaneous mouse mutation of Hoxd13 with a polyalanine expansion and phenotype similar to human synpolydactyly. , 1998, Human molecular genetics.
[6] T. Akiyama,et al. Axin, an inhibitor of the Wnt signalling pathway, interacts with β‐catenin, GSK‐3β and APC and reduces the β‐catenin level , 1998, Genes to cells : devoted to molecular & cellular mechanisms.
[7] Paul Polakis,et al. Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β , 1998, Current Biology.
[8] W. Birchmeier,et al. Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. , 1998, Science.
[9] W. Bodmer,et al. Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[10] A Luz,et al. Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts. , 1998, Gastroenterology.
[11] R. Nusse,et al. β-catenin: a key mediator of Wnt signaling , 1998 .
[12] T. Akiyama,et al. Localization of the adenomatous polyposis coli tumour suppressor protein in the mouse central nervous system , 1998, Neuroscience.
[13] J. Hegemann,et al. Mal3, the Fission Yeast Homologue of the Human APC-interacting Protein EB-1 Is Required for Microtubule Integrity and the Maintenance of Cell Form , 1997, Journal of Cell Biology.
[14] A. Markham,et al. The cellular distribution of the adenomatous polyposis coli tumour suppressor protein in neuroblastoma cells is regulated by microtubule dynamics , 1997, Neuroscience.
[15] A. Lowy,et al. Phosphorylation of the Tumor Suppressor Adenomatous Polyposis Coli (APC) by the Cyclin-dependent Kinase p34 cdc2 * , 1997, The Journal of Biological Chemistry.
[16] M. Pfreundschuh,et al. RP1, a new member of the adenomatous polyposis coli-binding EB1-like gene family, is differentially expressed in activated T cells. , 1997, Journal of immunology.
[17] K. Makino,et al. Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein , 1997, Oncogene.
[18] K. Mostov,et al. Dynamics of β-Catenin Interactions with APC Protein Regulate Epithelial Tubulogenesis , 1997, The Journal of cell biology.
[19] P. Polakis. The adenomatous polyposis coli (APC) tumor suppressor. , 1997, Biochimica et biophysica acta.
[20] T. Akiyama,et al. DAP‐1, a novel protein that interacts with the guanylate kinase‐like domains of hDLG and PSD‐95 , 1997, Genes to cells : devoted to molecular & cellular mechanisms.
[21] R. White,et al. Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[22] K. Kinzler,et al. Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma , 1997, Science.
[23] Hans Clevers,et al. Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC , 1997, Science.
[24] K. Mostov,et al. NH2-terminal Deletion of β-Catenin Results in Stable Colocalization of Mutant β-Catenin with Adenomatous Polyposis Coli Protein and Altered MDCK Cell Adhesion , 1997, The Journal of cell biology.
[25] J. Groden,et al. Characterization of 19 novel and six recurring APC mutations in Italian adenomatous polyposis patients, using two different mutation detection techniques , 1997 .
[26] J. Barber,et al. Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene. , 1996, American journal of human genetics.
[27] Rodney J. Scott,et al. Germline mutations in the 3′ part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli , 1996, Human Genetics.
[28] Michael Kühl,et al. Functional interaction of β-catenin with the transcription factor LEF-1 , 1996, Nature.
[29] Hans Clevers,et al. XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos , 1996, Cell.
[30] K. Kinzler,et al. Apoptosis and APC in colorectal tumorigenesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[31] C. L. Adams,et al. The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration , 1996, The Journal of cell biology.
[32] R. Kucherlapati,et al. Genotype-Phenotype Correlations in Intestinal Carcinogenesis: Lessons From Mouse Models , 1996 .
[33] T. Akiyama,et al. Binding of APC to the Human Homolog of the Drosophila Discs Large Tumor Suppressor Protein , 1996, Science.
[34] Paul Polakis,et al. Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly , 1996, Science.
[35] T. Akiyama,et al. The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase. , 1995, The EMBO journal.
[36] A. Moser,et al. Homozygosity for the Minallele of Apc results in disruption of mouse development prior to gastrulation , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.
[37] R. Brent,et al. APC binds to the novel protein EB1. , 1995, Cancer research.
[38] M Oshima,et al. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[39] P. Polakis,et al. Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[40] P. Polakis,et al. The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin. , 1995, The Journal of biological chemistry.
[41] K. Kinzler,et al. Inactivation of both APC alleles in human and mouse tumors. , 1994, Cancer research.
[42] R Fodde,et al. A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[43] P. Polakis,et al. The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. , 1994, Cancer research.
[44] T. Pollard,et al. Wild-type but not mutant APC associates with the microtubule cytoskeleton. , 1994, Cancer research.
[45] R. Bhat,et al. High levels of expression of the tumor suppressor gene APC during development of the rat central nervous system , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[46] K. Kinzler,et al. Association of the APC tumor suppressor protein with catenins. , 1993, Science.
[47] F. Masiarz,et al. Association of the APC gene product with beta-catenin. , 1993, Science.
[48] G. Joslyn,et al. Dimer formation by an N-terminal coiled coil in the APC protein. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[49] M. Emi,et al. Detailed analysis of genetic alterations in colorectal tumors from patients with and without familial adenomatous polyposis (FAP). , 1993, Oncogene.
[50] K. Kinzler,et al. Association between wild type and mutant APC gene products. , 1993, Cancer research.
[51] K. Kinzler,et al. The APC gene product in normal and tumor cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[52] Yusuke Nakamura,et al. Mutations of the APC adenomatous polyposis coli) gene , 1993, Human mutation.
[53] Bert Vogelstein,et al. APC mutations occur early during colorectal tumorigenesis , 1992, Nature.
[54] S Ichii,et al. Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. , 1992, Human molecular genetics.
[55] K. Kinzler,et al. Erratum: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene , 1992, Science.
[56] Margaret Robertson,et al. Identification and characterization of the familial adenomatous polyposis coli gene , 1991, Cell.
[57] K. Kinzler,et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. , 1991, Science.
[58] H. Pitot,et al. A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. , 1990, Science.
[59] B. Hogan,et al. Manipulating the mouse embryo: A laboratory manual , 1986 .
[60] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[61] G. Cunha. Hormonal influences on the morphogenesis of the preputial gland of embryonic mice , 1975, The Anatomical Record.
[62] M. R. Mickey,et al. Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids. , 1973, Journal of the National Cancer Institute.