Neurodegenerative disorders: Assessing the impact of natural vs drug‐induced treatment options
暂无分享,去创建一个
[1] Joong Sun Kim,et al. Neuroprotective effect of Geijigadaehwang-tang against trimethyltin-induced hippocampal neurodegeneration: An in vitro and in vivo study. , 2022, Journal of ethnopharmacology.
[2] G. Zyuz’kov,et al. Targeting cAMP-pathway in Regeneration-Competent Cells of Nervous Tissue: Potential to Create a Novel Drug for Treatment of Ethanol-Induced Neurodegeneration. , 2021, Central nervous system agents in medicinal chemistry.
[3] Stephen S. Lim,et al. The burden of neurological disorders across the states of India: the Global Burden of Disease Study 1990–2019 , 2021, The Lancet. Global health.
[4] S. Lipton,et al. Protein S-nitrosylation and oxidation contribute to protein misfolding in neurodegeneration. , 2021, Free radical biology & medicine.
[5] L. Ferraiuolo,et al. DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity , 2021, Cellular and Molecular Life Sciences.
[6] G. Cestra,et al. Chemical chaperones targeted to the endoplasmic reticulum (ER) and lysosome prevented neurodegeneration in a C9orf72 repeat expansion drosophila amyotrophic lateral sclerosis (ALS) model , 2021, Pharmacological Reports.
[7] Paul M. Levine,et al. O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity , 2021, Nature Chemistry.
[8] A. Abramov,et al. Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention , 2020, Medicinal research reviews.
[9] E. Potapova,et al. Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration , 2020, Life.
[10] D. Klenerman,et al. Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage‐gated calcium channels and NADPH oxidase , 2020, The FEBS journal.
[11] John D. Finan,et al. The Impact of Traumatic Brain Injury on Amyotrophic Lateral Sclerosis - From Bedside to Bench. , 2019, Journal of neurophysiology.
[12] M. Haque,et al. Thymoquinone prevents neurodegeneration against MPTP in vivo and modulates α-synuclein aggregation in vitro , 2019, Neurochemistry International.
[13] M. Faheem,et al. Neuroprotective effects of melatonin and celecoxib against ethanol-induced neurodegeneration: a computational and pharmacological approach , 2019, Drug design, development and therapy.
[14] Bing Zhang,et al. Preparation, optimization and cellular uptake study of tanshinone I nanoemulsion modified with lactoferrin for brain drug delivery , 2019, Pharmaceutical development and technology.
[15] Jun‐Seok Lee,et al. Crosstalk between Oxidative Stress and Tauopathy , 2019, International journal of molecular sciences.
[16] A. Azadi,et al. Brain Delivery of Curcumin Using Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Preparation, Optimization, and Pharmacokinetic Evaluation. , 2018, ACS chemical neuroscience.
[17] Nima Razzaghi-Asl,et al. The potential of natural product vs neurodegenerative disorders: In silico study of artoflavanocoumarin as BACE-1 inhibitor , 2018, Comput. Biol. Chem..
[18] B. Lu,et al. Altered ER–mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models , 2018, Proceedings of the National Academy of Sciences.
[19] J. Tamarit,et al. Iron in Friedreich Ataxia: A Central Role in the Pathophysiology or an Epiphenomenon? , 2018, Pharmaceuticals.
[20] Honglin Luo,et al. Enteroviral Infection: The Forgotten Link to Amyotrophic Lateral Sclerosis? , 2018, Front. Mol. Neurosci..
[21] A. Abramov,et al. Role of mitochondrial ROS in the brain: from physiology to neurodegeneration , 2018, FEBS letters.
[22] P. Sil,et al. Nutraceuticals: An emerging therapeutic approach against the pathogenesis of Alzheimer's disease , 2017, Pharmacological research.
[23] M. Tomás,et al. Oxidative stress and the amyloid beta peptide in Alzheimer’s disease , 2017, Redox biology.
[24] Kiwon Jung,et al. Beneficial effects of Panax ginseng for the treatment and prevention of neurodegenerative diseases: past findings and future directions , 2017, Journal of ginseng research.
[25] K. Caldecott,et al. Nonsyndromic cerebellar ataxias associated with disorders of DNA single-strand break repair. , 2018, Handbook of clinical neurology.
[26] Karsten Melcher,et al. Amyloid beta: structure, biology and structure-based therapeutic development , 2017, Acta Pharmacologica Sinica.
[27] K. Vossel,et al. Epileptic activity in Alzheimer's disease: causes and clinical relevance , 2017, The Lancet Neurology.
[28] A. Al-Chalabi,et al. What causes amyotrophic lateral sclerosis? , 2017, F1000Research.
[29] J. Frydman,et al. Protein misfolding in neurodegenerative diseases: implications and strategies , 2017, Translational Neurodegeneration.
[30] Norm Allaire,et al. SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage , 2017, Proceedings of the National Academy of Sciences.
[31] Hong Qing,et al. Epigenetics in Alzheimer’s Disease: Perspective of DNA Methylation , 2017, Molecular Neurobiology.
[32] D. Averill-Bates,et al. Activation of apoptosis signalling pathways by reactive oxygen species. , 2016, Biochimica et biophysica acta.
[33] Shengdi Chen,et al. Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson’s disease and Alzheimer’s disease , 2016, Progress in Neurobiology.
[34] M. Montazer,et al. Encapsulation of Aloe Vera extract into natural Tragacanth Gum as a novel green wound healing product. , 2016, International journal of biological macromolecules.
[35] R. Patnaik,et al. Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study. , 2016, Medical hypotheses.
[36] M. Kamal,et al. In Silico Analysis of Green Tea Polyphenols as Inhibitors of AChE and BChE Enzymes in Alzheimer's Disease Treatment. , 2016, CNS & neurological disorders drug targets.
[37] H. Mitsumoto,et al. Potential Environmental Factors in Amyotrophic Lateral Sclerosis. , 2015, Neurologic clinics.
[38] E. Carro,et al. Chitosan coated nanostructured lipid carriers for brain delivery of proteins by intranasal administration. , 2015, Colloids and surfaces. B, Biointerfaces.
[39] Mark E. Davis,et al. Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core , 2015, Proceedings of the National Academy of Sciences.
[40] M. Kim,et al. Melatonin ameliorates amyloid beta‐induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus , 2015, Journal of pineal research.
[41] Simon C. Dyall,et al. Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA , 2015, Front. Aging Neurosci..
[42] D. Klenerman,et al. Lipid peroxidation is essential for α‐synuclein‐induced cell death , 2015, Journal of neurochemistry.
[43] M. Cheetham,et al. The role of HSP70 and its co-chaperones in protein misfolding, aggregation and disease. , 2015, Sub-cellular biochemistry.
[44] M. Ciriolo,et al. Glutathione: new roles in redox signaling for an old antioxidant , 2014, Front. Pharmacol..
[45] Linqi Shi,et al. Maintenance of amyloid β peptide homeostasis by artificial chaperones based on mixed-shell polymeric micelles. , 2014, Angewandte Chemie.
[46] S. Vinogradov,et al. Targeted Nanogel Conjugate for Improved Stability and Cellular Permeability of Curcumin: Synthesis, Pharmacokinetics, and Tumor Growth Inhibition , 2014, Molecular pharmaceutics.
[47] L. Tsai,et al. DNA Damage and Its Links to Neurodegeneration , 2014, Neuron.
[48] D. Turnbull,et al. Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?☆ , 2014, Ageing Research Reviews.
[49] S. Ferreira,et al. How does brain insulin resistance develop in Alzheimer's disease? , 2014, Alzheimer's & Dementia.
[50] J. Walton. Chronic aluminum intake causes Alzheimer's disease: applying Sir Austin Bradford Hill's causality criteria. , 2014, Journal of Alzheimer's disease : JAD.
[51] Feng Gao,et al. A novel lactoferrin-modified β-cyclodextrin nanocarrier for brain-targeting drug delivery. , 2013, International journal of pharmaceutics.
[52] D. Hernandez,et al. A dominant mutation in FBXO38 causes distal spinal muscular atrophy with calf predominance. , 2013, American journal of human genetics.
[53] A. Nath,et al. Retroviruses and amyotrophic lateral sclerosis. , 2013, Antiviral research.
[54] J. Brodsky,et al. Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels. , 2013, ACS chemical neuroscience.
[55] J. Veltman,et al. Mutations in BICD2, which encodes a golgin and important motor adaptor, cause congenital autosomal-dominant spinal muscular atrophy. , 2013, American journal of human genetics.
[56] D. Standaert,et al. MHCII Is Required for α-Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration , 2013, The Journal of Neuroscience.
[57] S. Bahmanpour,et al. Neuroprotective Effects of NMDA and Group I Metabotropic Glutamate Receptor Antagonists Against Neurodegeneration Induced by Homocysteine in Rat Hippocampus: In Vivo Study , 2013, Journal of Molecular Neuroscience.
[58] J. Chen,et al. Cholesterol efflux is differentially regulated in neurons and astrocytes: implications for brain cholesterol homeostasis. , 2013, Biochimica et biophysica acta.
[59] A. Pestronk,et al. Mutations in the tail domain of DYNC1H1 cause dominant spinal muscular atrophy , 2012, Neurology.
[60] L. Stefanis. α-Synuclein in Parkinson's disease. , 2012, Cold Spring Harbor perspectives in medicine.
[61] S. Leurgans,et al. Cerebrovascular Disease Pathology and Parkinsonian Signs in Old Age , 2011, Stroke.
[62] Claudia Martini,et al. In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases , 2011, J. Comput. Aided Mol. Des..
[63] P. Wong,et al. Amyloid precursor protein processing and Alzheimer's disease. , 2011, Annual review of neuroscience.
[64] A. Koeppen. Friedreich's ataxia: Pathology, pathogenesis, and molecular genetics , 2011, Journal of the Neurological Sciences.
[65] J. Burgos,et al. Statins as neuroprotectants: a comparative in vitro study of lipophilicity, blood-brain-barrier penetration, lowering of brain cholesterol, and decrease of neuron cell death. , 2011, Journal of Alzheimer's disease : JAD.
[66] Pamela A McCombe,et al. Effects of gender in amyotrophic lateral sclerosis. , 2010, Gender medicine.
[67] W. Chingwaru,et al. The Role of Functional Foods, Nutraceuticals, and Food Supplements in Intestinal Health , 2010, Nutrients.
[68] G. Levy,et al. The relationship of Parkinson disease with aging. , 2007, Archives of neurology.
[69] K. Akiyoshi,et al. Inhibition of the formation of amyloid β‐protein fibrils using biocompatible nanogels as artificial chaperones , 2006, FEBS letters.
[70] Todd R. Flower,et al. α-Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease , 2006 .
[71] Todd R. Flower,et al. alpha-Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease. , 2006, FEMS yeast research.
[72] M. Youdim,et al. Novel multifunctional neuroprotective iron chelator‐monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition , 2005, Journal of neurochemistry.
[73] M. Hayden,et al. Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[74] F. Urano,et al. Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation. , 2005, Cell death and differentiation.
[75] F. Urano,et al. Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation , 2005, Cell Death and Differentiation.
[76] M. Mayer,et al. Hsp70 chaperones: Cellular functions and molecular mechanism , 2005, Cellular and Molecular Life Sciences.
[77] D. B. Min,et al. Reactive Oxygen Species, Aging, and Antioxidative Nutraceuticals. , 2004, Comprehensive reviews in food science and food safety.
[78] M. Vila,et al. Series Introduction: Neurodegeneration: What is it and where are we? , 2003 .
[79] J. Langston,et al. Environmental Risk Factors and Parkinson's Disease: Selective Degeneration of Nigral Dopaminergic Neurons Caused by the Herbicide Paraquat , 2002, Neurobiology of Disease.
[80] J. Olney,et al. Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain. , 2002, Brain research. Developmental brain research.
[81] S. Paul,et al. Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[82] J.. Neurodegenerative Diseases , 1996, GWUMC Department of Biochemistry and Molecular Biology Annual Spring Symposia.