Forum for debate: Safety of allogeneic blood transfusion alternatives in the surgical/critically ill patient.

[1]  M. McCaul,et al.  Antifibrinolytic drugs for acute traumatic injury. , 2016, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[2]  C. Fenger-Eriksen,et al.  [Tranexamic acid for upper gastrointestinal bleeding]. , 2016, Ugeskrift for laeger.

[3]  James A. Russell Faculty Opinions recommendation of Lower versus higher hemoglobin threshold for transfusion in septic shock. , 2015 .

[4]  I. Roberts,et al.  Antifibrinolytic drugs for acute traumatic injury. , 2015, The Cochrane database of systematic reviews.

[5]  L. Fleisher,et al.  Liberal versus restrictive blood transfusion strategy: 3-year survival and cause of death results from the FOCUS randomised controlled trial , 2015, The Lancet.

[6]  G. Angelini,et al.  Liberal or restrictive transfusion after cardiac surgery. , 2015, The New England journal of medicine.

[7]  J. Vincent,et al.  Transfusion Requirements in Surgical Oncology Patients: A Prospective, Randomized Controlled Trial , 2015, Anesthesiology.

[8]  L. Gluud,et al.  Tranexamic acid for upper gastrointestinal bleeding. , 2014, The Cochrane database of systematic reviews.

[9]  Janos Szebeni,et al.  Hypersensitivity reactions to intravenous iron: guidance for risk minimization and management , 2014, Haematologica.

[10]  Randomised trials of human albumin for adults with sepsis: systematic review and meta-analysis with trial sequential analysis of all-cause mortality , 2014, BMJ : British Medical Journal.

[11]  Julia S. Benoit,et al.  Effect of erythropoietin and transfusion threshold on neurological recovery after traumatic brain injury: a randomized clinical trial. , 2014, JAMA.

[12]  M. Porath,et al.  Transfusion policy after severe postpartum haemorrhage: a randomised non‐inferiority trial , 2014, BJOG : an international journal of obstetrics and gynaecology.

[13]  J. McLean Health Care-Associated Infection After Red Blood Cell Transfusion: A Systematic Review and Meta-analysis , 2014 .

[14]  J. Vincent,et al.  Isotonic crystalloid solutions: a structured review of the literature. , 2014, British journal of anaesthesia.

[15]  C. Sánchez,et al.  Controversias sobre la utilización de las soluciones de almidón (hidroxietil-almidones). ¿Está contraindicado el uso de hidroxietil-almidones de bajo peso molecular? , 2014 .

[16]  D. Spahn,et al.  III. Fibrinogen concentrate: clinical reality and cautious Cochrane recommendation. , 2014, British journal of anaesthesia.

[17]  J. Paramo,et al.  Antifibrinolytic agents in current anaesthetic practice: use of tranexamic acid in lower limb arthroplasty. , 2014, British journal of anaesthesia.

[18]  E. Martín-Montañez,et al.  Perioperative anemia management in colorectal cancer patients: a pragmatic approach. , 2014, World journal of gastroenterology.

[19]  E. Peterson,et al.  Patterns and outcomes of red blood cell transfusion in patients undergoing percutaneous coronary intervention. , 2014, JAMA.

[20]  M. Stroud,et al.  Intravenous fluid therapy for adults in hospital: summary of NICE guidance , 2013, BMJ.

[21]  D. Kansagara,et al.  Treatment of Anemia in Patients With Heart Disease , 2013 .

[22]  M. Parker Randomised trial of blood transfusion versus a restrictive transfusion policy after hip fracture surgery. , 2013, Injury.

[23]  S. Leal-Noval,et al.  Efficacy of the prothrombin complex concentrate prothromplex in patients requiring urgent reversal of vitamin K antagonists or presenting with uncontrolled bleeding: a retrospective, single center study , 2013, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

[24]  Sylvie Chevret,et al.  Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients presenting with hypovolemic shock: the CRISTAL randomized trial. , 2013, JAMA.

[25]  S. Lewis,et al.  Restrictive Versus Liberal Transfusion Strategies for Older Mechanically Ventilated Critically Ill Patients: A Randomized Pilot Trial* , 2013, Critical care medicine.

[26]  H. Almodaimegh,et al.  The use of preoperative erythropoiesis-stimulating agents (ESAs) in patients who underwent knee or hip arthroplasty: a meta-analysis of randomized clinical trials. , 2013, The Journal of arthroplasty.

[27]  I. Roberts,et al.  Systematic review, meta‐analysis and meta‐regression of the effect of tranexamic acid on surgical blood loss , 2013, The British journal of surgery.

[28]  C. Aldecoa,et al.  Tetrastarch solutions: are they definitely dead? , 2013, British journal of anaesthesia.

[29]  R. Wolterbeek,et al.  Safety and effects of two red blood cell transfusion strategies in pediatric cardiac surgery patients: a randomized controlled trial , 2013, Intensive Care Medicine.

[30]  J. Wetterslev,et al.  Fibrinogen concentrate in bleeding patients. , 2013, The Cochrane database of systematic reviews.

[31]  K. Ho,et al.  Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials , 2013, BMJ.

[32]  M. Jacob,et al.  Hydroxyethyl starch - the importance of being earnest , 2013, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

[33]  J. Goldstein,et al.  Efficacy and Safety of a 4-Factor Prothrombin Complex Concentrate in Patients on Vitamin K Antagonists Presenting With Major Bleeding: A Randomized, Plasma-Controlled, Phase IIIb Study , 2013, Circulation.

[34]  T. J. Morgan The ideal crystalloid – what is ‘balanced’? , 2013, Current opinion in critical care.

[35]  A. Girbes,et al.  Re-evaluating currently available data and suggestions for planning randomised controlled studies regarding the use of hydroxyethyl starch in critically ill patients - a multidisciplinary statement , 2013, Critical Care.

[36]  K. Ker,et al.  Topical application of tranexamic acid for the reduction of bleeding. , 2013, The Cochrane database of systematic reviews.

[37]  T. Waldhör,et al.  Iron Deficiency Generates Secondary Thrombocytosis and Platelet Activation in IBD: the Randomized, Controlled ThromboVIT Trial , 2013, Inflammatory bowel diseases.

[38]  Regina M. Hardison,et al.  Liberal versus restrictive transfusion thresholds for patients with symptomatic coronary artery disease. , 2013, American heart journal.

[39]  P. Wouters,et al.  Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. , 2013, European journal of anaesthesiology.

[40]  Wim Van Biesen,et al.  Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: a European Renal Best Practice position statement. , 2013, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[41]  E. Vamvakas Reasons for moving toward a patient‐centric paradigm of clinical transfusion medicine practice , 2013, Transfusion.

[42]  Akshay S. Desai,et al.  Treatment of anemia with darbepoetin alfa in systolic heart failure. , 2013, The New England journal of medicine.

[43]  P. Meybohm,et al.  Aprotinin May Increase Mortality in Low and Intermediate Risk but Not in High Risk Cardiac Surgical Patients Compared to Tranexamic Acid and ε-Aminocaproic Acid – A Meta-Analysis of Randomised and Observational Trials of over 30.000 Patients , 2013, PloS one.

[44]  A. Cayuela,et al.  Red blood cell transfusion in non-bleeding critically ill patients with moderate anemia: is there a benefit? , 2013, Intensive Care Medicine.

[45]  P. Perel,et al.  Tranexamic acid for reducing mortality in emergency and urgent surgery. , 2013, The Cochrane database of systematic reviews.

[46]  J. Wetterslev,et al.  Association of blood transfusion with increased mortality in myocardial infarction: a meta-analysis and diversity-adjusted study sequential analysis. , 2013, JAMA internal medicine.

[47]  M. Poca,et al.  Transfusion strategies for acute upper gastrointestinal bleeding. , 2013, The New England journal of medicine.

[48]  A. Hanke,et al.  Effects of Fibrinogen Concentrate as First-line Therapy during Major Aortic Replacement Surgery: A Randomized, Placebo-controlled Trial , 2013, Anesthesiology.

[49]  Hyo Youl Kim,et al.  Red blood cell transfusions are associated with lower mortality in patients with severe sepsis and septic shock: A propensity-matched analysis* , 2012, Critical care medicine.

[50]  R. Bellomo,et al.  Hydroxyethyl starch or saline for fluid resuscitation in intensive care. , 2012, The New England journal of medicine.

[51]  Michael Bailey,et al.  Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults. , 2012, JAMA.

[52]  C. Samama,et al.  Reversal of Vitamin K Antagonist (VKA) effect in patients with severe bleeding: a French multicenter observational study (Optiplex) assessing the use of Prothrombin Complex Concentrate (PCC) in current clinical practice , 2012, Critical Care.

[53]  C. Samama,et al.  How can we explain the gap between randomised studies and 'real life' practice in postoperative transfusion triggers? Do we need to change recommended thresholds for transfusion? , 2012, European journal of anaesthesiology.

[54]  C. Mazer,et al.  Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies , 2012, BMJ : British Medical Journal.

[55]  D. Spahn,et al.  Effects of Allogeneic Red Blood Cell Transfusions on Clinical Outcomes in Patients Undergoing Colorectal Cancer Surgery: A Systematic Review and Meta-Analysis , 2012, Annals of surgery.

[56]  J. Tenhunen,et al.  Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis. , 2012, The New England journal of medicine.

[57]  S. Kleinman,et al.  Red Blood Cell Transfusion: A Clinical Practice Guideline From the AABB* , 2012, Annals of Internal Medicine.

[58]  E. Williams,et al.  Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): A randomised, placebo-controlled trial , 2012, Indian Journal of Neurotrauma.

[59]  R. Jaeschke,et al.  Safety of gelatin for volume resuscitation—a systematic review and meta-analysis , 2012, Intensive Care Medicine.

[60]  M. Carvalho,et al.  Prothrombin complex concentrate (Octaplex): a Portuguese experience in 1152 patients , 2012, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

[61]  N. Dahl,et al.  Thrombocytosis and venous thromboembolism in cancer patients with chemotherapy induced anemia may be related to ESA induced iron restricted erythropoiesis and reversed by administration of IV iron , 2012, American journal of hematology.

[62]  C. Sprung,et al.  Consensus statement of the ESICM task force on colloid volume therapy in critically ill patients , 2012, Intensive Care Medicine.

[63]  S. Schulman,et al.  Thromboembolic safety and efficacy of prothrombin complex concentrates in the emergency reversal of warfarin coagulopathy. , 2012, Thrombosis research.

[64]  M. Colomina,et al.  Appropriateness of red blood cell use in orthopedic surgery and traumatology: analysis of transfusion practice , 2012, European Journal of Orthopaedic Surgery & Traumatology.

[65]  P. Austin,et al.  Surgical outcomes and transfusion of minimal amounts of blood in the operating room. , 2012, Archives of surgery.

[66]  Hynek Pikhart,et al.  Methods to decrease blood loss and transfusion requirements for liver transplantation. , 2011, Cochrane Database of Systematic Reviews.

[67]  A. Hanke,et al.  First-line therapy with coagulation factor concentrates combined with point-of-care coagulation testing is associated with decreased allogeneic blood transfusion in cardiovascular surgery: a retrospective, single-center cohort study. , 2011, Anesthesiology.

[68]  D. Kansagara,et al.  Treatment of Anemia in Patients with Heart Disease: A Systematic Review [Internet] , 2011 .

[69]  S. Leal-Noval,et al.  Impact of national transfusion indicators on appropriate blood usage in critically ill patients , 2011, Transfusion.

[70]  W. Ageno,et al.  Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists , 2011, Thrombosis and Haemostasis.

[71]  K. Ker,et al.  Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion. , 2011, The Cochrane database of systematic reviews.

[72]  R. Rossaint,et al.  Clinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity , 2011, Critical care.

[73]  J. García-Erce,et al.  Disorders of iron metabolism. Part II: iron deficiency and iron overload , 2010, Journal of Clinical Pathology.

[74]  D. Annane,et al.  A balanced view of balanced solutions , 2010, Critical care.

[75]  D. Spahn Anemia and Patient Blood Management in Hip and Knee Surgery: A Systematic Review of the Literature , 2010, Anesthesiology.

[76]  R. Peto,et al.  Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial , 2010, The Lancet.

[77]  M. Bauer,et al.  Anemia and blood transfusion in a surgical intensive care unit , 2010, Critical care.

[78]  F. Roila,et al.  Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients: ESMO Clinical Practice Guidelines for use. , 2010, Annals of oncology : official journal of the European Society for Medical Oncology.

[79]  H. Reichmann,et al.  Recombinant Human Erythropoietin in the Treatment of Acute Ischemic Stroke , 2009, Stroke.

[80]  C. Stowell,et al.  An Open-Label, Randomized, Parallel-Group Study of Perioperative Epoetin Alfa Versus Standard of Care for Blood Conservation in Major Elective Spinal Surgery: Safety Analysis , 2009, Spine.

[81]  Ajay Kumar Perioperative management of anemia: Limits of blood transfusion and alternatives to it , 2009, Cleveland Clinic Journal of Medicine.

[82]  H. Takagi,et al.  Aprotinin increases mortality as compared with tranexamic acid in cardiac surgery: a meta-analysis of randomized head-to-head trials. , 2009, Interactive cardiovascular and thoracic surgery.

[83]  S. R. Leal-Noval,et al.  [Is there still a role for recombinant erythropoietin in the management of anaemia of critical illness?]. , 2009, Medicina clinica.

[84]  H. Kehlet,et al.  The effects of liberal versus restrictive transfusion thresholds on ambulation after hip fracture surgery , 2009, Transfusion.

[85]  Rolf Rossaint,et al.  Intensive insulin therapy and pentastarch resuscitation in severe sepsis. , 2008, The New England journal of medicine.

[86]  C. Sprung,et al.  Are Blood Transfusions Associated with Greater Mortality Rates?: Results of the Sepsis Occurrence in Acutely Ill Patients Study , 2008, Anesthesiology.

[87]  T. Kubo,et al.  [Perioperative changes of blood coagulability evaluated by thromboelastography (TEG) in patients undergoing total knee and total hip arthroplasty]. , 2007, Masui. The Japanese journal of anesthesiology.

[88]  C. Samama,et al.  Do Antifibrinolytics Reduce Allogeneic Blood Transfusion in Orthopedic Surgery? , 2006, Anesthesiology.

[89]  M. Muñoz,et al.  Documento «Sevilla» de Consenso sobre Alternativas a la Transfusión de Sangre Alogénica , 2006 .

[90]  G. Wells,et al.  A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. , 1999, The New England journal of medicine.

[91]  L. Leibovici,et al.  The safety of intravenous iron preparations: systematic review and meta-analysis. , 2015, Mayo Clinic proceedings.

[92]  J. Wetterslev,et al.  Hemoglobin threshold for transfusion in septic shock. , 2015, The New England journal of medicine.

[93]  D. Spahn,et al.  Fibrinogen concentrate : clinical reality and cautious Cochrane recommendation , 2014 .

[94]  N. Freemantle,et al.  Putting the record straight on aprotinin as safe and effective: results from a mixed treatment meta-analysis of trials of aprotinin. , 2013, The Journal of thoracic and cardiovascular surgery.

[95]  J. Myburgh,et al.  Resuscitation fluids. , 2013, The New England journal of medicine.

[96]  A. E. D. M. Y. P. Sanitarios Preparados de hierro de administración intravenosa y reacciones de hipersensibilidad: nuevas recomendaciones , 2013 .

[97]  É. Azoulay,et al.  Safety of performing fiberoptic bronchoscopy in critically ill hypoxemic patients with acute respiratory failure , 2012, Intensive Care Medicine.

[98]  A. Menkis,et al.  Seizures following cardiac surgery: the impact of tranexamic acid and other risk factors , 2011, Canadian Journal of Anesthesia/Journal canadien d'anesthésie.

[99]  黄亚明,et al.  European Society of Intensive Care Medicine , 2005, Intensive Care Medicine.

[100]  RESEARCH Open Access Management of bleeding and coagulopathy following major trauma: an updated European , 2022 .