A mouse model links asthma susceptibility to prenatal exposure to diesel exhaust.

[1]  J. Suen,et al.  A common environmental pollutant, 4‐nonylphenol, promotes allergic lung inflammation in a murine model of asthma , 2013, Allergy.

[2]  Shau-ku Huang,et al.  PHAGOCYTES , GRANULOCYTES , AND MYELOPOIESIS Aryl hydrocarbon receptor controls murine mast cell homeostasis , 2013 .

[3]  Inhibition of endotoxin‐induced perinatal asthma protection by pollutants in an experimental mouse model , 2013, Allergy.

[4]  A. Comellas,et al.  Protein kinase C-ζ mediates lung injury induced by diesel exhaust particles. , 2013, American journal of respiratory cell and molecular biology.

[5]  F. Perera,et al.  Early-life cockroach allergen and polycyclic aromatic hydrocarbon exposures predict cockroach sensitization among inner-city children. , 2013, The Journal of allergy and clinical immunology.

[6]  E. Israel,et al.  Lipoxin A4 Regulates Natural Killer Cell and Type 2 Innate Lymphoid Cell Activation in Asthma , 2013, Science Translational Medicine.

[7]  W. M. Foster,et al.  Maternal diesel inhalation increases airway hyperreactivity in ozone-exposed offspring. , 2012, American journal of respiratory cell and molecular biology.

[8]  L. Akinbami,et al.  National surveillance of asthma: United States, 2001-2010. , 2012, Vital & health statistics. Series 3, Analytical and epidemiological studies.

[9]  M. Lommatzsch.  Airway Hyperresponsiveness: New Insights into the Pathogenesis , 2012, Seminars in Respiratory and Critical Care Medicine.

[10]  M. Colombo,et al.  The Aryl Hydrocarbon Receptor Modulates Acute and Late Mast Cell Responses , 2012, The Journal of Immunology.

[11]  Ling Lu,et al.  IL-17A-producing NK cells were implicated in liver injury induced by ischemia and reperfusion. , 2012, International immunopharmacology.

[12]  J. T. Chang,et al.  Aryl hydrocarbon receptor in association with RelA modulates IL-6 expression in non-smoking lung cancer , 2012, Oncogene.

[13]  D. Cook,et al.  Prenatal and Passive Smoke Exposure and Incidence of Asthma and Wheeze: Systematic Review and Meta-analysis , 2012, Pediatrics.

[14]  Antonia M. Calafat,et al.  Prenatal Exposure to Bisphenol A and Child Wheeze from Birth to 3 Years of Age , 2012, Environmental health perspectives.

[15]  Y. Fujitani,et al.  Effects of nanoparticle-rich diesel exhaust particles on IL-17 production in vitro , 2012, Journal of Immunotoxicology.

[16]  Lidia Morawska,et al.  Respiratory health effects of diesel particulate matter , 2012, Respirology.

[17]  Liang Zhou,et al.  The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells. , 2012, Immunity.

[18]  Hua Huang,et al.  ERK1 is important for Th2 differentiation and development of experimental asthma , 2012, The FASEB Journal.

[19]  E. Hobeika,et al.  Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles , 2011, Science.

[20]  D. Remick,et al.  Cardiovascular , Pulmonary , and Renal Pathology Diesel Exhaust Particulates Exacerbate Asthma-Like Inflammation by Increasing CXC Chemokines , 2011 .

[21]  Andrew Rundle,et al.  Traffic density and stationary sources of air pollution associated with wheeze, asthma, and immunoglobulin E from birth to age 5 years among New York City children. , 2011, Environmental research.

[22]  L. Boon,et al.  Activation of the aryl hydrocarbon receptor suppresses sensitization in a mouse peanut allergy model. , 2011, Toxicological sciences : an official journal of the Society of Toxicology.

[23]  Yongjian Xu,et al.  Increased expression of aryl hydrocarbon receptor and interleukin 22 in patients with allergic asthma. , 2011, Asian Pacific journal of allergy and immunology.

[24]  B. Levy,et al.  NK Cells Are Effectors for Resolvin E1 in the Timely Resolution of Allergic Airway Inflammation , 2011, The Journal of Immunology.

[25]  F. Perera,et al.  Prenatal exposure to polycyclic aromatic hydrocarbons, environmental tobacco smoke and asthma. , 2011, Respiratory medicine.

[26]  P. Foster,et al.  An Alternate STAT6-Independent Pathway Promotes Eosinophil Influx into Blood during Allergic Airway Inflammation , 2011, PloS one.

[27]  Joseph C. Sun,et al.  Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection , 2011, The Journal of experimental medicine.

[28]  M. Veldhoen,et al.  The aryl hydrocarbon receptor: fine-tuning the immune-response. , 2010, Current opinion in immunology.

[29]  S. Jeong,et al.  Asian dust and titanium dioxide particles–induced inflammation and oxidative DNA damage in C57BL/6 mice , 2010, Inhalation toxicology.

[30]  D. Raulet,et al.  Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment , 2010, The Journal of experimental medicine.

[31]  C. Ple,et al.  Natural Killer Cells Accumulate in Lung‐Draining Lymph Nodes and Regulate Airway Eosinophilia in a Murine Model of Asthma , 2010, Scandinavian journal of immunology.

[32]  M. Caligiuri,et al.  Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue. , 2010, Immunity.

[33]  Zhi Ning,et al.  Ambient ultrafine particles provide a strong adjuvant effect in the secondary immune response: implication for traffic-related asthma flares. , 2010, American journal of physiology. Lung cellular and molecular physiology.

[34]  R. Luebke,et al.  Effects of prenatal diesel exhaust inhalation on pulmonary inflammation and development of specific immune responses. , 2010, Toxicology letters.

[35]  F. Perera,et al.  Intrauterine exposure to polycyclic aromatic hydrocarbons, fine particulate matter and early wheeze. Prospective birth cohort study in 4‐year olds , 2010, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[36]  F. Perera,et al.  Prenatal allergen and diesel exhaust exposure and their effects on allergy in adult offspring mice , 2010, Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology.

[37]  R. Alam,et al.  Uncoordinated 119 Preferentially Induces Th2 Differentiation and Promotes the Development of Asthma , 2010, The Journal of Immunology.

[38]  Kiros Berhane,et al.  Childhood Incident Asthma and Traffic-Related Air Pollution at Home and School , 2010, Environmental health perspectives.

[39]  C. Hunter,et al.  IL-6 Promotes NK Cell Production of IL-17 during Toxoplasmosis , 2010, The Journal of Immunology.

[40]  F. Muskens,et al.  Both Conventional and Interferon Killer Dendritic Cells Have Antigen-Presenting Capacity during Influenza Virus Infection , 2009, PloS one.

[41]  Emily A. Stevens,et al.  The aryl hydrocarbon receptor: a perspective on potential roles in the immune system , 2009, Immunology.

[42]  D. Jarvis,et al.  Association between modelled traffic-related air pollution and asthma score in the ECRHS , 2009, European Respiratory Journal.

[43]  N. Goplen,et al.  Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma. , 2009, The Journal of allergy and clinical immunology.

[44]  Petros Koutrakis,et al.  Symptoms and Medication Use in Children with Asthma and Traffic-Related Sources of Fine Particle Pollution , 2009, Environmental health perspectives.

[45]  M. E. Hahn,et al.  Regulation of constitutive and inducible AHR signaling: complex interactions involving the AHR repressor. , 2009, Biochemical pharmacology.

[46]  M. Veldhoen,et al.  Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells , 2009, The Journal of experimental medicine.

[47]  J. Douwes,et al.  Farm exposure in utero may protect against asthma, hay fever and eczema , 2008, European Respiratory Journal.

[48]  J. Buer,et al.  The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins , 2008, Nature.

[49]  Eric Vivier,et al.  Functions of natural killer cells , 2008, Nature Immunology.

[50]  Lester Kobzik,et al.  Pulmonary exposure to particles during pregnancy causes increased neonatal asthma susceptibility. , 2008, American journal of respiratory cell and molecular biology.

[51]  Pamela Ohman-Strickland,et al.  Respiratory effects of exposure to diesel traffic in persons with asthma. , 2007, The New England journal of medicine.

[52]  T. Nutman,et al.  Filarial Parasites Induce NK Cell Activation, Type 1 and Type 2 Cytokine Secretion, and Subsequent Apoptotic Cell Death1 , 2007, The Journal of Immunology.

[53]  M. Gaestel,et al.  MK2 controls the level of negative feedback in the NF-κB pathway and is essential for vascular permeability and airway inflammation , 2007, The Journal of experimental medicine.

[54]  Charles Ris,et al.  U.S. EPA Health Assessment for Diesel Engine Exhaust: A Review , 2007, Inhalation toxicology.

[55]  M. Fujii,et al.  Polycyclic aromatic hydrocarbons aggravate antigen-induced nasal blockage in experimental allergic rhinitis. , 2007, Journal of pharmacological sciences.

[56]  K. Bock,et al.  Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions. , 2006, Biochemical pharmacology.

[57]  M. Madden,et al.  Effects of diesel exhaust particles on human alveolar macrophage ability to secrete inflammatory mediators in response to lipopolysaccharide. , 2006, Toxicology in vitro : an international journal published in association with BIBRA.

[58]  B. Wallaert,et al.  Diesel exhaust exposure favors TH2 cell recruitment in nonatopic subjects by differentially regulating chemokine production. , 2006, The Journal of allergy and clinical immunology.

[59]  B. Brunekreef,et al.  Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. , 2006, The Journal of allergy and clinical immunology.

[60]  Kiros Berhane,et al.  Traffic, Susceptibility, and Childhood Asthma , 2006, Environmental health perspectives.

[61]  T. Sandström,et al.  Airway antioxidant and inflammatory responses to diesel exhaust exposure in healthy humans , 2006, European Respiratory Journal.

[62]  Masayuki Yamamoto,et al.  Effects of Aryl Hydrocarbon Receptor Signaling on the Modulation of Th1/Th2 Balance1 , 2005, The Journal of Immunology.

[63]  F. Gonzalez,et al.  Over‐production of IFN‐γ and IL‐12 in AhR‐null mice , 2005 .

[64]  H. Aburatani,et al.  Constitutive Expression of Aryl Hydrocarbon Receptor in Keratinocytes Causes Inflammatory Skin Lesions , 2005, Molecular and Cellular Biology.

[65]  T. Matsushita,et al.  Abnormal natural killer cell function in systemic sclerosis: altered cytokine production and defective killing activity. , 2005, The Journal of investigative dermatology.

[66]  D. Bernstein,et al.  Is it traffic type, volume, or distance? Wheezing in infants living near truck and bus traffic. , 2005, The Journal of allergy and clinical immunology.

[67]  D. Warshawsky,et al.  Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review. , 2005, Toxicology and applied pharmacology.

[68]  C. Akdis,et al.  Different natural killer (NK) receptor expression and immunoglobulin E (IgE) regulation by NK1 and NK2 cells , 2005, Clinical and experimental immunology.

[69]  R. Sun,et al.  Involvement of human natural killer cells in asthma pathogenesis: natural killer 2 cells in type 2 cytokine predominance. , 2005, The Journal of allergy and clinical immunology.

[70]  M. Kadiiska,et al.  Synergistic production of lung free radicals by diesel exhaust particles and endotoxin. , 2005, American journal of respiratory and critical care medicine.

[71]  Ning Li,et al.  Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals1 , 2004, The Journal of Immunology.

[72]  F. Lauer,et al.  Environmental polycyclic aromatic hydrocarbons, benzo(a) pyrene (BaP) and BaP-quinones, enhance IgE-mediated histamine release and IL-4 production in human basophils. , 2003, Clinical immunology.

[73]  R. Luebke,et al.  Suppression of allergic immune responses to house dust mite (HDM) in rats exposed to 2,3,7,8-TCDD. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.

[74]  T. Sandström,et al.  Diesel exhaust enhances airway responsiveness in asthmatic subjects. , 2001, The European respiratory journal.

[75]  A. Nel,et al.  In vivo nasal challenge with diesel exhaust particles enhances expression of the CC chemokines rantes, MIP-1alpha, and MCP-3 in humans. , 2000, Clinical immunology.

[76]  P. Cullinan,et al.  Airway inflammation after controlled exposure to diesel exhaust particulates. , 2000, American journal of respiratory and critical care medicine.

[77]  M. Li‐Weber,et al.  The environmental pollutant pyrene induces the production of IL-4. , 2000, The Journal of allergy and clinical immunology.

[78]  S T Holgate,et al.  Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. , 1999, American journal of respiratory and critical care medicine.

[79]  H. Ljunggren,et al.  Natural Killer Cells Determine Development of Allergen-induced Eosinophilic Airway Inflammation in Mice , 1999, The Journal of experimental medicine.

[80]  A E Nel,et al.  Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune system. , 1998, The Journal of allergy and clinical immunology.

[81]  S. Cammisuli,et al.  IL-5 production by NK cells contributes to eosinophil infiltration in a mouse model of allergic inflammation. , 1998, Journal of immunology.

[82]  A. Litonjua,et al.  Parental history and the risk for childhood asthma. Does mother confer more risk than father? , 1998, American journal of respiratory and critical care medicine.

[83]  H. Takano,et al.  Diesel exhaust enhances allergic airway inflammation and hyperresponsiveness in mice. , 1998, American journal of respiratory and critical care medicine.

[84]  R. Hagemann,et al.  The adjuvant activity of diesel exhaust particles and carbon black on systemic IgE production to ovalbumin in mice after intranasal instillation. , 1997, Toxicology.

[85]  D. Diat-Sanchez,et al.  The role of diesel exhaust particles and their associated polyaromatic hydrocarbons in the induction of allergic airway disease , 1997 .

[86]  R. Bravo,et al.  Monocyte chemotactic protein-3 (MCP-3)/fibroblast-induced cytokine (FIC) in eosinophilic inflammation of the airways and the inhibitory effects of an anti-MCP-3/FIC antibody. , 1997, Journal of immunology.

[87]  S. Durham,et al.  Upregulation of αGM-CSF-receptor in nonatopic asthma but not in atopic asthma ☆ ☆☆ ★ ★★ , 1997 .

[88]  A. Saxon,et al.  Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a T helper cell 2-type pattern. , 1997, Journal of immunology.

[89]  S. Durham,et al.  Upregulation of alpha GM-CSF-receptor in nonatopic asthma but not in atopic asthma. , 1997, The Journal of allergy and clinical immunology.

[90]  M. Sears,et al.  Parental and neonatal risk factors for atopy, airway hyper-responsiveness, and asthma. , 1996, Archives of disease in childhood.

[91]  J. Reddy,et al.  Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[92]  T. Suzuki,et al.  Adjuvant activities of pyrene, anthracene, fluoranthene and benzo(a)pyrene in production of anti-IgE antibody to Japanese cedar pollen allergen in mice. , 1996, Journal of clinical & laboratory immunology.

[93]  H. Fujimaki,et al.  Intranasal instillation of diesel exhaust particulates and antigen in mice modulated cytokine productions in cervical lymph node cells. , 1995, International archives of allergy and immunology.

[94]  H. Fujimaki,et al.  IL-4 production in mediastinal lymph node cells in mice intratracheally instilled with diesel exhaust particulates and antigen. , 1994, Toxicology.

[95]  T. Suzuki,et al.  The adjuvant activity of pyrene in diesel exhaust on IgE antibody production in mice. , 1993, Arerugi = [Allergy].

[96]  D. M. Kemény,et al.  Higher risk of infantile atopic dermatitis from maternal atopy than from paternal atopy , 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[97]  T. Miyamoto,et al.  Adjuvant activity of diesel-exhaust particulates for the production of IgE antibody in mice. , 1986, The Journal of allergy and clinical immunology.

[98]  P. Srivastava,et al.  Fetal translocation and metabolism of PAH obtained from coal fly ash given intratracheally to pregnant rats. , 1986, Journal of toxicology and environmental health.

[99]  F. Dixon,et al.  IMMUNOLOGIC UNRESPONSIVENESS INDUCED BY PROTEIN ANTIGENS , 1955, The Journal of experimental medicine.

[100]  P. Medawar,et al.  ‘Actively Acquired Tolerance’ of Foreign Cells , 1953, Nature.