Impact of red blood cell transfusion on regional cerebral oxygen saturation during pediatric ECMO

Low cerebral regional tissue oxygenation (crSO2) is associated with unfavorable neurological outcomes in children requiring extracorporeal membrane oxygenation (ECMO) support. Red blood cell (RBC) transfusion can improve brain oxygenation and crSO2 has been proposed as a noninvasive monitoring tool that could aid in RBC transfusion decision‐making. However, how crSO2 responds to RBC transfusion is largely unknown.

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