Novel Study Antimicrobial and Biocompatibility Effect of Magnesium Silver Alloys 1% on Bovine Bacterial Species

MgAg 1% alloys inhibit bacterial growth during the dry-off period. MgAg1% silver and magnesium amount was determined and the supernatant was used for the detection of antibacterial tests against S. aureus and E. coli and Geobacillus stearothermophilus var. calidolacits. The antibacterial effect of AgNO3 solution and degradation medium of MgAg1% sticks were evaluated. The bouillon dilution test showed a 5-fold reduction in bacterial colonies. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) calculations were used to test the antibacterial activity. The Brilliant Black Reduction Test (BRT-MRL screening test) showed inhibition of Geobacillus stearothermophilus bacteria at AgNO3 concentrations 0.01 mmol/l and 3 ml of degradation medium. Results were satisfying, concerning biocompatibility, degradation, and antibacterial effects.

[1]  D. Gkentzi,et al.  Antimicrobial Properties on Non-Antibiotic Drugs in the Era of Increased Bacterial Resistance , 2020, Antibiotics.

[2]  F. Feyerabend,et al.  Influence of the Microstructure and Silver Content on Degradation, Cytocompatibility, and Antibacterial Properties of Magnesium-Silver Alloys In Vitro , 2017, Oxidative medicine and cellular longevity.

[3]  Y. Nomier.  In vitro and ex ovo studies of biocompatibility of magnesium-silver alloys and their antimicrobial effects on bovine bacterial species , 2011 .

[4]  G. Kazmer,et al.  Antibacterial effect of plant-derived antimicrobials on major bacterial mastitis pathogens in vitro. , 2009, Journal of dairy science.

[5]  P. Lacasse,et al.  Mammary tissue damage during bovine mastitis: causes and control. , 2008, Journal of animal science.

[6]  Y. Park,et al.  Antibacterial Activity and Mechanism of Action of the Silver Ion in Staphylococcus aureus and Escherichia coli , 2008, Applied and Environmental Microbiology.

[7]  P. Martus,et al.  Reduced rates of catheter-associated infection by use of a new silver-impregnated central venous catheter , 2007, Infection.

[8]  K. G. A. Hameed,et al.  Public health hazard due to mastitis in dairy cows , 2007 .

[9]  Alexis M Pietak,et al.  Magnesium and its alloys as orthopedic biomaterials: a review. , 2006, Biomaterials.

[10]  J. Hillerton,et al.  Treating mastitis in the cow – a tradition or an archaism , 2005, Journal of applied microbiology.

[11]  J. Trevors,et al.  Mobilization ofEscherichia coli R1 silver-resistance plasmid pJT1 by Tn5-Mob intoEscherichia coli C600 , 2005, Biology of Metals.

[12]  A. Lansdown,et al.  Silver. I: Its antibacterial properties and mechanism of action. , 2002, Journal of wound care.

[13]  G. Pulverer,et al.  Efficacy of silver-coated medical devices. , 1998, The Journal of hospital infection.

[14]  A D Russell,et al.  Antimicrobial activity and action of silver. , 1994, Progress in medicinal chemistry.

[15]  M. Harms-Ringdahl,et al.  Stimulating effects of mercuric- and silver ions on the superoxide anion production in human polymorphonuclear leukocytes. , 1993, Free radical research communications.

[16]  R C Tilton,et al.  Reversal of the silver inhibition of microorganisms by agar , 1978, Applied and environmental microbiology.