Initial Experience of Percutaneous Extraction of Infected Cardiac Implantable Electric Devices Using Excimer Laser

Background:The estimated incidence of infected cardiac implantable electric devices (CIED)has recently increased to 1% -2%.Prompt removal of infected devices improves survival rates.We describe our initial experience of lead extraction from infected devices using an excimer laser that was approved for this application in 2010. Methods and results:We retrospectively analyzed the characteristics,type of devices and leads,as well as indications and complications in 13 patients with CIED infection between 2011 and 2014 at our hospital. The clinical presentation comprised isolated pocket infection(n=12),lead endocarditis(n=3)and methicillinresistant Staphylococcus aureus-positive blood cultures.The patients had been implanted with a total of 29 leads(atrial,n=13;ventricular,n=16)for a median duration of 10.2±5.2 years.The procedure was successful in all patients,but two patients who developed recurrent infection required repeated removal of devices and an implant device from epicardial cardiac muscle.Acute cardiac tamponade occurred in one patient after ventricular lead extraction due to perforation of the right ventricle. This patient required an emergency thoracotomy,but was discharged one month after the procedure. Conclusion :Infected CIED leads can be quickly extracted using an excimer laser.Shinshu Med J 63 :103― 108, 2015 (Received for publication August 18,2014;accepted in revised form November 28,2014)

[1]  W. Shimizu,et al.  Initial experience using Excimer laser for the extraction of chronically implanted pacemaker and implantable cardioverter defibrillator leads in Japanese patients. , 2013, Journal of cardiology.

[2]  U. Birgersdotter-Green,et al.  Device Infections: Management and Indications for Lead Extraction , 2013, Circulation.

[3]  S. Cha,et al.  Clinical features and outcomes of cardiovascular implantable electronic device infections due to staphylococcal species. , 2012, The American journal of cardiology.

[4]  Gilbert Habib,et al.  Long-term outcomes following infection of cardiac implantable electronic devices: a prospective matched cohort study , 2012, Heart.

[5]  M. Chung,et al.  Cardiovascular Implantable Electronic Device Replacement Infections and Prevention: Results from the REPLACE Registry , 2012, Pacing and clinical electrophysiology : PACE.

[6]  S. Cha,et al.  Impact of timing of device removal on mortality in patients with cardiovascular implantable electronic device infections. , 2011, Heart rhythm.

[7]  W. Wojciechowska,et al.  Left ventricular lead implantation at a phrenic stimulation site is safe and effective. , 2011, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[8]  U. Wiegand Delayed cure from CIED infections: losing only time without risk for patient outcome? , 2010, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[9]  A. Haverich,et al.  Treatment of patients with recurrent or persistent infection of cardiac implantable electronic devices. , 2010, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[10]  B. Wilkoff,et al.  Cardiac implantable electronic device infections: presentation, management, and patient outcomes. , 2010, Heart rhythm.

[11]  David O. Martin,et al.  Initial experience with the Evolution mechanical dilator sheath for lead extraction: safety and efficacy. , 2010, Heart rhythm.

[12]  S. Worley,et al.  Excimer laser to open refractory subclavian occlusion in 12 consecutive patients. , 2010, Heart rhythm.

[13]  C. Ervin,et al.  Lead extraction in the contemporary setting: the LExICon study: an observational retrospective study of consecutive laser lead extractions. , 2010, Journal of the American College of Cardiology.

[14]  D. Sánchez-Quintana,et al.  Anatomic evaluation of the left phrenic nerve relevant to epicardial and endocardial catheter ablation: implications for phrenic nerve injury. , 2009, Heart rhythm.

[15]  Vince Paul,et al.  Laser-assisted lead extraction: the European experience. , 2007, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[16]  D Lacroix,et al.  Local symptoms at the site of pacemaker implantation indicate latent systemic infection , 2004, Heart.

[17]  T. D. Sellers,et al.  Clinical Study of the Laser Sheath for Lead Extraction: The Total Experience in the United States , 2002, Pacing and clinical electrophysiology : PACE.

[18]  David Longworth,et al.  Diagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices , 2000, Annals of Internal Medicine.

[19]  D L Hayes,et al.  Pacemaker lead extraction with the laser sheath: results of the pacing lead extraction with the excimer sheath (PLEXES) trial. , 1999, Journal of the American College of Cardiology.