Craniopharyngioma with Intratumoral Hemorrhage and Superficial Siderosis

Superficial siderosis of the central nervous system (CNS) is a rare condition caused by deposition of hemosiderin in the brain and spinal cord. The typical clinical manifestation of superficial siderosis includes sensorineural hearing loss, gait ataxia and pyramidal signs (1). The chronic existence of bleeding source in the subarachnoid space results in the deposition of hemosiderin in the subpial layer of the CNS (2). The source of bleeding is variable, including vascular malformations, trauma, CNS tumors, and CNS surgery (1, 3). Craniopharyngioma is a rare brain tumor and intratumoral hemorrhage is one of the uncommon manifestations of craniopharyngioma (4). Also, superficial siderosis associated with craniopharyngioma is rarely reported in previous studies (3). We report a rare case superficial siderosis associated with craniopharyngioma with intratumoral hemorrhage.