Methotrexate‐associated lymphoproliferative disorder presenting as giant ulcers on the leg

1 Bombi L., Bongjun S, Insop S. Phellodendron amurense and its major alkaloid compound, berberine ameliorates scopolamine-induced neuronal impairment and memory dysfunction in rats. Korean J Physiol Pharmacol 2012; 16: 79–89. 2 Kim JH, Huh JE, Baek YH. Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes. J Ethnopharmacol 2011; 134: 234–42. 3 Xian YF, Mao QQ, Ip SP. Comparison on the antiinflammatory effect of Cortex Phellodendri Chinensis and Cortex Phellodendri Amurensis in 12-O-tetradecanoylphorbol-13-acetate-induced ear edema in mice. J Ethnopharmacol 2011; 137: 1425–30. 4 Veraldi S, Barbareschi M, Guanziroli E. Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres. G Ital Dermatol Venereol 2015; 150: 143–7.

[1]  F. Lewis,et al.  Paroxysmal purple palmar macules with a rare aetiology , 2017, Clinical and experimental dermatology.

[2]  M. Krem,et al.  Methotrexate-associated primary cutaneous CD30-positive cutaneous T-cell lymphoproliferative disorder: a case illustration and a brief review. , 2016, American journal of blood research.

[3]  J. Wada,et al.  Acute idiopathic blue fingers: a young man with Achenbach's syndrome , 2016, BMJ Case Reports.

[4]  O. Ishikawa,et al.  Methotrexate-associated lymphoproliferative disorder: Sequential development of angioimmunoblastic T-cell lymphoma-like lymphoproliferation in the lymph nodes and diffuse large B-cell lymphoma in the skin in the same patient , 2015, European Journal of Dermatology.

[5]  Y. Fukasawa,et al.  Cutaneous manifestations of methotrexate-associated lymphoproliferative disorders: report of two cases and a review of the literature. , 2015, Acta dermato-venereologica.

[6]  H. Matsuoka,et al.  Methotrexate-associated lymphoproliferative disorders: management by watchful waiting and observation of early lymphocyte recovery after methotrexate withdrawal , 2015, Leukemia & lymphoma.

[7]  R. Willemze,et al.  Methotrexate-associated B-cell Lymphoproliferative Disorders Presenting in the Skin: A Clinicopathologic and Immunophenotypical Study of 10 Cases , 2014, The American journal of surgical pathology.

[8]  Y. Tomita,et al.  Lymphoproliferative disorders in rheumatoid arthritis: clinicopathological analysis of 76 cases in relation to methotrexate medication. , 2007, The Journal of rheumatology.