Synthesis of scutellarein derivatives to increase biological activity and water solubility.
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Yuping Tang | Pengxuan Zhang | Nianguang Li | Ting Gu | Wen-Yu Wu | Ze-Xi Dong | Zhi-Hao Shi | He-Min Li | Qianping Shi | Wei Zhang | Fang Fang | Xin-xue | Jian‐Ping Yang | Jin-Ao Duan | Zhi‐Hao Shi
[1] Nianguang Li,et al. Mannich bases of scutellarein as thrombin-inhibitors: design, synthesis, biological activity and solubility. , 2012, Bioorganic & medicinal chemistry.
[2] Nianguang Li,et al. Metabolism-based synthesis, biologic evaluation and SARs analysis of O-methylated analogs of quercetin as thrombin inhibitors. , 2012, European journal of medicinal chemistry.
[3] A. Ding,et al. Synthesis and Bio-Activity Evaluation of Scutellarein as a Potent Agent for the Therapy of Ischemic Cerebrovascular Disease , 2011, International journal of molecular sciences.
[4] Zai-Qun Liu. Chemical methods to evaluate antioxidant ability. , 2010, Chemical reviews.
[5] Xinlai Cheng,et al. Synthesis and cytotoxicity of novel indirubin-5-carboxamides. , 2010, Bioorganic & medicinal chemistry.
[6] Jingjing Miao,et al. Immune responses, ROS generation and the haemocyte damage of scallop Chlamys farreri exposed to Aroclor 1254. , 2009, Fish & shellfish immunology.
[7] H. Choo,et al. In vitro solubility, stability and permeability of novel quercetin-amino acid conjugates. , 2009, Bioorganic & medicinal chemistry.
[8] Yanjie Lu,et al. Scutellarin‐induced endothelium‐independent relaxation in rat aorta , 2008, Phytotherapy research : PTR.
[9] V. Makarov,et al. Inhibition of thrombin and factor Xa by Fucus evanescens fucoidan and its modified analogs , 2008, Bulletin of Experimental Biology and Medicine.
[10] Eric Therrien,et al. Design, synthesis, and thrombin-inhibitory activity of pyridin-2-ones as P2/P3 core motifs. , 2008, Bioorganic & medicinal chemistry letters.
[11] Q. You,et al. A novel and efficient route to the construction of the 4-oxa-tricyclo[4.3.1.0]decan-2-one scaffold , 2007 .
[12] Jing Li,et al. Antioxidant activity of polyaniline nanofibers , 2007 .
[13] C. Napoli,et al. Nitric oxide and atherosclerosis: an update. , 2006, Nitric oxide : biology and chemistry.
[14] Huibi Xu,et al. Effect of scutellarin on nitric oxide production in early stages of neuron damage induced by hydrogen peroxide. , 2005, Pharmacological research.
[15] H. Hong,et al. Scutellarin Attenuates Oxidative Glutamate Toxicity in PC12 Cells , 2004, Planta medica.
[16] Wei He,et al. Effects of scutellarin on liver function after brain ischemia/reperfusion in rats. , 2003, Acta pharmacologica Sinica.
[17] S. Wnendt,et al. Synthesis and immunological activity of water-soluble thalidomide prodrugs. , 2001, Bioorganic & medicinal chemistry.
[18] S. Cuzzocrea,et al. Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. , 2001, Pharmacological reviews.
[19] L. Greene,et al. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. , 1976, Proceedings of the National Academy of Sciences of the United States of America.
[20] Nianguang Li,et al. Design, synthesis and biological evaluation of glucose-containing scutellarein derivatives as neuroprotective agents based on metabolic mechanism of scutellarin in vivo. , 2013, Bioorganic & medicinal chemistry letters.
[21] Nianguang Li,et al. Design, Synthesis and Biological Evaluation of Scutellarein Derivatives as Potential Anti-Alzheimers Disease Candidates Based on Metabolic Mechanism , 2012 .
[22] Feng Zhang,et al. Synthetic studies on the construction of 7-O-methylquercetin through regioselective protection and alkylation of quercetin , 2011 .
[23] Quanbin Zhang,et al. Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica. , 2010, International journal of biological macromolecules.
[24] S. Kaushal,et al. Journal of Translational Medicine BioMed Central , 2008 .