Higher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin Levels
暂无分享,去创建一个
K. Hasegawa | K. Koike | M. Kurano | K. Enooku | Baasanjav Uranbileg | H. Ikeda | Y. Yatomi | N. Kokudo | Hiroki Kudo | Masaya Sato | Harufumi Maki | B. Uranbileg | H. Maki
[1] William Wheeler,et al. Female chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome , 2016, Nature Communications.
[2] T. Tsujiuchi,et al. Diverse effects of LPA4, LPA5 and LPA6 on the activation of tumor progression in pancreatic cancer cells. , 2015, Biochemical and biophysical research communications.
[3] P. Winter,et al. Lysophosphatidic acid receptor LPAR6 supports the tumorigenicity of hepatocellular carcinoma. , 2015, Cancer research.
[4] K. Koike,et al. Increased serum autotaxin levels in hepatocellular carcinoma patients were caused by background liver fibrosis but not by carcinoma. , 2014, Clinica chimica acta; international journal of clinical chemistry.
[5] G. Gores,et al. Hepatocellular carcinoma: clinical frontiers and perspectives , 2014, Gut.
[6] Jacob H. Swet,et al. Lysophosphatidic acid receptor expression and function in human hepatocellular carcinoma. , 2013, The Journal of surgical research.
[7] Y. Inoue,et al. Autotaxin as a novel serum marker of liver fibrosis. , 2011, Clinica chimica acta; international journal of clinical chemistry.
[8] G. Mills,et al. Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression , 2011, Oncogene.
[9] J. Chun,et al. The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine. , 2010, American journal of physiology. Gastrointestinal and liver physiology.
[10] H. Imamura,et al. AFP, AFP-L3, DCP, and GP73 as markers for monitoring treatment response and recurrence and as surrogate markers of clinicopathological variables of HCC , 2010, Journal of Gastroenterology.
[11] Yiling Lu,et al. Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells. , 2008, Journal of the National Cancer Institute.
[12] M. Nöthen,et al. G protein–coupled receptor P2Y5 and its ligand LPA are involved in maintenance of human hair growth , 2008, Nature Genetics.
[13] D. Gordon,et al. Disruption of P2RY5, an orphan G protein–coupled receptor, underlies autosomal recessive woolly hair , 2008, Nature Genetics.
[14] M. Nangaku,et al. Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. , 2008, Clinica chimica acta; international journal of clinical chemistry.
[15] M. Omata,et al. Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity. , 2007, Life sciences.
[16] Kazuhiro Nakamura,et al. Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C , 2007, Journal of clinical gastroenterology.
[17] H. Arai,et al. Measurement of lysophospholipase D/autotaxin activity in human serum samples. , 2007, Clinical biochemistry.
[18] E. Rogaev,et al. Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene LIPH , 2006, Science.
[19] Y. Kishi,et al. Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid* , 2006, Journal of Biological Chemistry.
[20] C. Mummery,et al. Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development , 2006, Molecular and Cellular Biology.
[21] H. Nagawa,et al. Differential expression of lysophosphatidic acid receptor‐2 in intestinal and diffuse type gastric cancer , 2006, Journal of surgical oncology.
[22] B. Giepmans,et al. The ins and outs of lysophosphatidic acid signaling , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.
[23] Y. Inoue,et al. Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells. , 2003, American journal of physiology. Gastrointestinal and liver physiology.
[24] Y. Inoue,et al. Functional diversity between Rho-kinase- and MLCK-mediated cytoskeletal actions in a myofibroblast-like hepatic stellate cell line. , 2003, Biochemical and biophysical research communications.
[25] R. Taguchi,et al. Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways* , 2002, The Journal of Biological Chemistry.
[26] K. Fukuzawa,et al. Identification of Human Plasma Lysophospholipase D, a Lysophosphatidic Acid-producing Enzyme, as Autotaxin, a Multifunctional Phosphodiesterase* , 2002, The Journal of Biological Chemistry.
[27] R. Taguchi,et al. A Novel Phosphatidic Acid-selective Phospholipase A1That Produces Lysophosphatidic Acid* , 2002, The Journal of Biological Chemistry.
[28] G. Mills,et al. Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production , 2002, The Journal of cell biology.
[29] Daniel L Baker,et al. Plasma lysophosphatidic acid concentration and ovarian cancer. , 2002, JAMA.
[30] S. Hirohashi,et al. Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho‐associated protein kinase inhibitor Y‐27632 , 2001, Hepatology.
[31] H. Ikeda,et al. Lysophosphatidic acid enhances collagen gel contraction by hepatic stellate cells: association with rho-kinase. , 2000, Biochemical and biophysical research communications.
[32] S. Hirohashi,et al. Cell motility mediated by rho and rho‐associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma , 1999, Hepatology.
[33] M. Kawabata,et al. Effects of lysophosphatidic acid on proliferation of stellate cells and hepatocytes in culture. , 1998, Biochemical and biophysical research communications.
[34] H. Higgs,et al. Cloning of a Phosphatidic Acid-preferring Phospholipase A1 from Bovine Testis* , 1998, The Journal of Biological Chemistry.
[35] L. Liotta,et al. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein. , 1992, The Journal of biological chemistry.
[36] D. Woodfield. Hepatocellular carcinoma. , 1986, The New Zealand medical journal.