Prediction of the autism spectrum disorder diagnosis with linear discriminant analysis classifier and K-nearest neighbor in children

Autism Spectrum Disorder (ASD) negatively affects the whole life of people. The main indications of ASD are seen as lack of social interaction and communication, repetitive patterns of behavior, fixed interests and activities. It is very important that ASD is diagnosed at an early age. In this study, the classification method for ASD diagnosis was used in children aged 4–11 years. The Linear Discriminant Analysis (LDA) and The K-Nearest Neighbor (KNN) algorithms are used for classification. To test the algorithms, 30 percent of the data set was selected as test data and 70 percent as training data. As a result of the work done; In the LDA algorithm, the accuracy is 90.8%, whereas the accuracy of the KNN algorithm is 88.5%. For the LDA algorithm, sensitivity and specificity values are calculated as 0.9524 and .08667, respectively. For KNN algorithm, these values are calculated as 0.9762 and 0.80. F-measure values are calculated as 0.9091 for the LDA algorithm and 0.8913 for the KNN algorithm.

[1]  B. H. Lo,et al.  Autism Spectrum Disorder , 2018, Journal of paediatrics and child health.

[2]  Fadi Thabtah,et al.  Autism Spectrum Disorder Screening: Machine Learning Adaptation and DSM-5 Fulfillment , 2017, ICMHI.

[3]  Jessica R. Jones,et al.  Changes in prevalence of parent-reported autism spectrum disorder in school-aged U.S. children: 2007 to 2011-2012. , 2013, National health statistics reports.

[4]  Yun Jiao,et al.  Predictive models of autism spectrum disorder based on brain regional cortical thickness , 2010, NeuroImage.

[5]  Li Yi,et al.  Identifying children with autism spectrum disorder based on their face processing abnormality: A machine learning framework , 2016, Autism research : official journal of the International Society for Autism Research.

[6]  A. Ganapathiraju,et al.  LINEAR DISCRIMINANT ANALYSIS - A BRIEF TUTORIAL , 1995 .

[7]  Rama Chellappa,et al.  Empirical performance analysis of linear discriminant classifiers , 1998, Proceedings. 1998 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (Cat. No.98CB36231).

[8]  Janaina Mourão Miranda,et al.  Investigating the predictive value of whole-brain structural MR scans in autism: A pattern classification approach , 2010, NeuroImage.

[9]  Z. Warren,et al.  Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014 , 2018, Morbidity and mortality weekly report. Surveillance summaries.

[10]  Amit Jain,et al.  Integrating independent components and linear discriminant analysis for gender classification , 2004, Sixth IEEE International Conference on Automatic Face and Gesture Recognition, 2004. Proceedings..

[11]  Kim Van Naarden Braun,et al.  Development of a Machine Learning Algorithm for the Surveillance of Autism Spectrum Disorder , 2016, PloS one.

[12]  Yang Wang,et al.  Cost-sensitive boosting for classification of imbalanced data , 2007, Pattern Recognit..