论文信息 - Extracellular ATP Induces Phosphatidylserine Externalization Earlier than Nuclear Apoptotic Events in Thymocytes - 字舞流文

Extracellular ATP Induces Phosphatidylserine Externalization Earlier than Nuclear Apoptotic Events in Thymocytes

Abstract: The present study shows for the first time that ATPec induces a very early PS exposure in thymocytes and that this process can be induced in the absence of Ca2+ influx and caspase activation.

F. Giraud | M. Courageot | J. Sulpice | S. Lépine

[1] V. Fadok,et al. Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. , 2001, The Journal of clinical investigation.

[2] B. Freedman,et al. ATP‐evoked Ca2+ transients and currents in murine thymocytes: possible role for P2X receptors in death by neglect , 1999, European journal of immunology.

[3] M. Sitkovsky,et al. Effects of extracellular ATP and adenosine on different thymocyte subsets: possible role of ATP-gated channels and G protein-coupled purinergic receptor. , 1997, Journal of immunology.

[4] P. Devaux,et al. Maintenance and consequences of membrane phospholipid asymmetry , 1994 .

[5] J. D. Young,et al. Extracellular ATP as a trigger for apoptosis or programmed cell death , 1991, The Journal of cell biology.