Rapid Three-Dimensional Photoacoustic Imaging Reconstruction for Irregularly Layered Heterogeneous Media

Photoacoustic imaging (PAI) is susceptible to speed of sound (SOS) differences in heterogeneous media which greatly reduce the resolutions and qualities of the imaging results. Several reconstruction methods have been reported to adapt for heterogenous media, but they are limited by specific deficiencies such as efficiency, accuracy, and model limitation problems. Among them, the plane wave model based on wavefield reconstruction is the most efficient and promising one for high-efficiency three-dimensional PAI. However, the classic plane wave model only suits for planar layered media, severely limiting its applications in practice. To this end, we modify the plane wave model to apply for irregularly layered heterogeneous media and propose a corresponding wavefield extrapolation to reconstruct photoacoustic image. This method employs split-step Fourier to compensate the SOS differences, extrapolates wavefields and reconstructs the image depth by depth. Furthermore, a floating discretization strategy is introduced to control and balance the efficiency and accuracy with a hyperparameter. The simulation and experiment results demonstrate that the proposed method can reconstruct the image with an equivalent resolution to time reversal’s and even have higher efficiency and robustness. To reconstruct a three-dimensional image with $50\times {50}\times 600$ pixels, the proposed method takes only 5.5 seconds using a laptop loaded with Intel(R) Core (TM) i7-8550U CPU @1.8GHz.

[1]  Chao Huang,et al.  Aberration correction for transcranial photoacoustic tomography of primates employing adjunct image data. , 2012, Journal of biomedical optics.

[2]  Lihong V. Wang,et al.  Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs , 2012, Science.

[3]  Yuanjin Zheng,et al.  Passive ultrasound aided acoustic resolution photoacoustic microscopy imaging for layered heterogeneous media , 2018, Applied Physics Letters.

[4]  Mark A. Anastasio,et al.  Image reconstruction in photoacoustic tomography with variable speed of sound using a higher order geometrical acoustics approximation , 2009, BiOS.

[5]  Thomas P. Matthews,et al.  Joint reconstruction of the initial pressure and speed of sound distributions from combined photoacoustic and ultrasound tomography measurements , 2017, Inverse problems.

[6]  M. Kronbichler,et al.  Photoacoustic image reconstruction: material detection and acoustical heterogeneities , 2017 .

[7]  Yuanjin Zheng,et al.  Fast and High-Resolution Three-Dimensional Hybrid-Domain Photoacoustic Imaging Incorporating Analytical-Focused Transducer Beam Amplitude , 2019, IEEE Transactions on Medical Imaging.

[8]  Ashkan Javaherian,et al.  A Multi-Grid Iterative Method for Photoacoustic Tomography , 2016, IEEE Transactions on Medical Imaging.

[9]  B T Cox,et al.  k-space propagation models for acoustically heterogeneous media: application to biomedical photoacoustics. , 2007, The Journal of the Acoustical Society of America.

[10]  Linong Liu,et al.  3D wavefield extrapolation with optimum split-step Fourier method , 2006 .

[11]  Vasilis Ntziachristos,et al.  Effects of small variations of speed of sound in optoacoustic tomographic imaging. , 2014, Medical physics.

[12]  Vasilis Ntziachristos,et al.  Accurate Model-Based Reconstruction Algorithm for Three-Dimensional Optoacoustic Tomography , 2012, IEEE Transactions on Medical Imaging.

[13]  Keji Yang,et al.  A blind deconvolution method for attenuative materials based on asymmetrical Gaussian model. , 2016, The Journal of the Acoustical Society of America.

[14]  Keji Yang,et al.  Sparse deconvolution method for ultrasound images based on automatic estimation of reference signals. , 2016, Ultrasonics.

[15]  T Olofsson Phase shift migration for imaging layered objects and objects immersed in water , 2010, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[16]  Linh V. Nguyen,et al.  Reconstruction and time reversal in thermoacoustic tomography in acoustically homogeneous and inhomogeneous media , 2008 .

[17]  V. Ntziachristos,et al.  Acoustic Inversion in Optoacoustic Tomography: A Review , 2013, Current medical imaging reviews.

[18]  Lihong V. Wang,et al.  Numerical investigation of the effects of shear waves in transcranial photoacoustic tomography with a planar geometry. , 2012, Journal of biomedical optics.

[19]  Jon F. Claerbout,et al.  Coarse grid calculations of waves in inhomogeneous media with application to delineation of complicated seismic structure , 1970 .

[20]  Bradley E. Treeby,et al.  Artifact Trapping During Time Reversal Photoacoustic Imaging for Acoustically Heterogeneous Media , 2010, IEEE Transactions on Medical Imaging.

[21]  Robert W Schoonover,et al.  Image reconstruction in photoacoustic tomography involving layered acoustic media. , 2011, Journal of the Optical Society of America. A, Optics, image science, and vision.

[22]  D. Angus,et al.  The One-Way Wave Equation: A Full-Waveform Tool for Modeling Seismic Body Wave Phenomena , 2014, Surveys in Geophysics.

[23]  Mark A. Anastasio,et al.  Full-Wave Iterative Image Reconstruction in Photoacoustic Tomography With Acoustically Inhomogeneous Media , 2013, IEEE Transactions on Medical Imaging.

[24]  Vasilis Ntziachristos,et al.  Statistical Approach for Optoacoustic Image Reconstruction in the Presence of Strong Acoustic Heterogeneities , 2011, IEEE Transactions on Medical Imaging.

[25]  Stewart A. Levin,et al.  Principle of reverse-time migration , 1984 .

[26]  R. Stolt MIGRATION BY FOURIER TRANSFORM , 1978 .

[27]  Mark A Anastasio,et al.  A simple Fourier transform-based reconstruction formula for photoacoustic computed tomography with a circular or spherical measurement geometry. , 2012, Physics in medicine and biology.

[28]  Lihong V Wang,et al.  Photoacoustic microscopy and computed tomography: from bench to bedside. , 2014, Annual review of biomedical engineering.

[29]  Yuanjin Zheng,et al.  Handheld Photoacoustic Imager for Theranostics in 3D , 2019, IEEE Transactions on Medical Imaging.

[30]  Wiendelt Steenbergen,et al.  Speed-of-sound compensated photoacoustic tomography for accurate imaging. , 2012, Medical physics.

[31]  Lihong V. Wang,et al.  A practical guide to photoacoustic tomography in the life sciences , 2016, Nature Methods.

[32]  Robert W Schoonover,et al.  Compensation of shear waves in photoacoustic tomography with layered acoustic media. , 2011, Journal of the Optical Society of America. A, Optics, image science, and vision.

[33]  Lihong V. Wang,et al.  Effects of acoustic heterogeneities on transcranial brain imaging with microwave-induced thermoacoustic tomography. , 2008, Medical physics.

[34]  F. N. Frenkiel,et al.  Waves In Layered Media , 1960 .

[35]  Yuan Xu,et al.  Exact frequency-domain reconstruction for thermoacoustic tomography. I. Planar geometry , 2002, IEEE Transactions on Medical Imaging.

[36]  Kui Ren,et al.  A one-step reconstruction algorithm for quantitative photoacoustic imaging , 2015, 1507.02776.

[37]  L. Trefethen,et al.  Wide-angle one-way wave equations. , 1988, The Journal of the Acoustical Society of America.

[38]  Thomas Berer,et al.  Photoacoustic tomography using integrating line detectors , 2010 .

[39]  Paul L. Stoffa,et al.  Split-Step Fourier Migration , 1990 .