RNA tectonics: towards RNA design.

[1]  G. Mohr,et al.  A tyrosyl-tRNA synthetase suppresses structural defects in the two major helical domains of the group I intron catalytic core. , 1996, Journal of molecular biology.

[2]  E Westhof,et al.  Structural Basis of Ligand Discrimination by Two Related RNA Aptamers Resolved by NMR Spectroscopy , 1996, Science.

[3]  E. Westhof,et al.  Mapping in three dimensions of regions in a catalytic RNA protected from attack by an Fe(II)-EDTA reagent. , 1996, Journal of molecular biology.

[4]  D. Patel,et al.  Molecular recognition in the FMN-RNA aptamer complex. , 1996, Journal of molecular biology.

[5]  P. Zarrinkar,et al.  The kinetic folding pathway of the Tetrahymena ribozyme reveals possible similarities between RNA and protein folding , 1996, Nature Structural Biology.

[6]  P. S. Kim,et al.  Context-dependent secondary structure formation of a designed protein sequence , 1996, Nature.

[7]  G. Varani,et al.  Specificity of ribonucleoprotein interaction determined by RNA folding during complex formation , 1996, Nature.

[8]  G. Mohr,et al.  A tyrosyl-tRNA synthetase protein induces tertiary folding of the group I intron catalytic core. , 1996, Journal of molecular biology.

[9]  James W. Brown,et al.  Comparative analysis of ribonuclease P RNA using gene sequences from natural microbial populations reveals tertiary structural elements. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[10]  E Westhof,et al.  Solution structure of mRNA hairpins promoting selenocysteine incorporation in Escherichia coli and their base-specific interaction with special elongation factor SELB. , 1996, RNA.

[11]  F. Cohen,et al.  Conformational switching in designed peptides: the helix/sheet transition. , 1996, Folding & design.

[12]  E. Westhof,et al.  A novel RNA structural motif in the selenocysteine insertion element of eukaryotic selenoprotein mRNAs. , 1996, RNA.

[13]  P. Hagerman,et al.  The influence of symmetric internal loops on the flexibility of RNA. , 1996, Journal of molecular biology.

[14]  E. Westhof,et al.  A central pseudoknotted three-way junction imposes tRNA-like mimicry and the orientation of three 5' upstream pseudoknots in the 3' terminus of tobacco mosaic virus RNA. , 1996, RNA.

[15]  K. Weeks,et al.  Assembly of a Ribonucleoprotein Catalyst by Tertiary Structure Capture , 1996, Science.

[16]  D. Lilley,et al.  The global folding of four-way helical junctions in RNA, including that in U1 snRNA , 1995, Cell.

[17]  D. Herschlag RNA Chaperones and the RNA Folding Problem (*) , 1995, The Journal of Biological Chemistry.

[18]  A. Klug,et al.  The crystal structure of an AII-RNAhammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage , 1995, Cell.

[19]  D. Crothers,et al.  Bent helix formation between RNA hairpins with complementary loops. , 1995, Science.

[20]  D. Crothers,et al.  Determinants of RNA hairpin loop-loop complex stability. , 1995, Journal of molecular biology.

[21]  I. Tinoco,et al.  The structure of an RNA pseudoknot that causes efficient frameshifting in mouse mammary tumor virus. , 1995, Journal of molecular biology.

[22]  F E Cohen,et al.  Prion protein peptides induce alpha-helix to beta-sheet conformational transitions. , 1995, Biochemistry.

[23]  J. Doudna,et al.  Self-assembly of a group I intron active site from its component tertiary structural domains. , 1995, RNA.

[24]  F. Michel,et al.  Frequent use of the same tertiary motif by self‐folding RNAs. , 1995, The EMBO journal.

[25]  T. Pan,et al.  Higher order folding and domain analysis of the ribozyme from Bacillus subtilis ribonuclease P. , 1995, Biochemistry.

[26]  Chantal Ehresmann,et al.  Molecular dissection of the pseudoknot governing the translational regulation of Escherichia coli ribosomal protein S15. , 1995, Nucleic Acids Res..

[27]  Nobutoshi Ito,et al.  Crystal structure at 1.92 Å resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin , 1994, Nature.

[28]  K. Flaherty,et al.  Three-dimensional structure of a hammerhead ribozyme , 1994, Nature.

[29]  K. Flaherty,et al.  Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix , 1994, Nature.

[30]  A. E. Walter,et al.  Coaxial stacking of helixes enhances binding of oligoribonucleotides and improves predictions of RNA folding. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[31]  T. Cech,et al.  Coaxially stacked RNA helices in the catalytic center of the Tetrahymena ribozyme. , 1994, Science.

[32]  S. Stern,et al.  Interactions of a small RNA with antibiotic and RNA ligands of the 30S subunit , 1994, Nature.

[33]  P. Zarrinkar,et al.  Kinetic intermediates in RNA folding. , 1994, Science.

[34]  G. F. Joyce,et al.  Inventing and improving ribozyme function: rational design versus iterative selection methods. , 1994, Trends in biotechnology.

[35]  P. Burgstaller,et al.  Isolation of RNA Aptamers for Biological Cofactors by In Vitro Selection , 1994 .

[36]  E. Westhof,et al.  A three-dimensional model of hepatitis delta virus ribozyme based on biochemical and mutational analyses , 1994, Current Biology.

[37]  E Westhof,et al.  Involvement of a GNRA tetraloop in long-range RNA tertiary interactions. , 1994, Journal of molecular biology.

[38]  J. Davies,et al.  Peptide antibiotics of the tuberactinomycin family as inhibitors of group I intron RNA splicing. , 1994, Journal of molecular biology.

[39]  Michael Famulok,et al.  Molecular Recognition of Amino Acids by RNA-Aptamers: An L-Citrulline Binding RNA Motif and Its Evolution into an L-Arginine Binder , 1994 .

[40]  T. Cech,et al.  GAAA tetraloop and conserved bulge stabilize tertiary structure of a group I intron domain. , 1994, Journal of molecular biology.

[41]  T. Cech,et al.  Visualization of a tertiary structural domain of the Tetrahymena group I intron by electron microscopy. , 1994, Journal of molecular biology.

[42]  E. Westhof,et al.  Solution structure of the 3'-end of brome mosaic virus genomic RNAs. Conformational mimicry with canonical tRNAs. , 1994, Journal of molecular biology.

[43]  E Westhof,et al.  Monitoring of the cooperative unfolding of the sunY group I intron of bacteriophage T4. The active form of the sunY ribozyme is stabilized by multiple interactions with 3' terminal intron components. , 1993, Journal of molecular biology.

[44]  C. Kundrot,et al.  Crystallization of ribozymes and small RNA motifs by a sparse matrix approach. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[45]  C. Ehresmann,et al.  Minimal 16S rRNA binding site and role of conserved nucleotides in Escherichia coli ribosomal protein S8 recognition. , 1993, European journal of biochemistry.

[46]  R. Schroeder,et al.  Splice-site selection and decoding: are they related? , 1993, Science.

[47]  T. Cech,et al.  An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme. , 1993, Biochemistry.

[48]  T. Cech,et al.  Movement of the guide sequence during RNA catalysis by a group I ribozyme. , 1993, Science.

[49]  D. Libri,et al.  Pre‐mRNA secondary structure and the regulation of splicing , 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.

[50]  G. Varani,et al.  The conformation of loop E of eukaryotic 5S ribosomal RNA. , 1993, Biochemistry.

[51]  J. Karn,et al.  Recognition of the high affinity binding site in rev-response element RNA by the human immunodeficiency virus type-1 rev protein. , 1992, Nucleic acids research.

[52]  E. Dam,et al.  Structural and functional aspects of RNA pseudoknots. , 1992, Biochemistry.

[53]  A. Lambowitz,et al.  A tyrosyl-tRNA synthetase binds specifically to the group I intron catalytic core. , 1992, Genes & development.

[54]  C. Barrow,et al.  NMR studies of amyloid beta-peptides: proton assignments, secondary structure, and mechanism of an alpha-helix----beta-sheet conversion for a homologous, 28-residue, N-terminal fragment. , 1992, Biochemistry.

[55]  M. Belfort,et al.  The neurospora CYT-18 protein suppresses defects in the phage T4 td intron by stabilizing the catalytically active structure of the intron core , 1992, Cell.

[56]  E. Westhof,et al.  Function of P11, a tertiary base pairing in self-splicing introns of subgroup IA. , 1991, Journal of Molecular Biology.

[57]  E. Westhof,et al.  Three-dimensional model of Escherichia coli ribosomal 5 S RNA as deduced from structure probing in solution and computer modeling. , 1991, Journal of molecular biology.

[58]  A. T. Perrotta,et al.  A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA , 1991, Nature.

[59]  E. Westhof,et al.  Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis. , 1990, Journal of molecular biology.

[60]  E. Wagner,et al.  Control of replication of plasmid R1: structures and sequences of the antisense RNA, CopA, required for its binding to the target RNA, CopT. , 1990, The EMBO journal.

[61]  J. Szostak,et al.  In vitro selection of RNA molecules that bind specific ligands , 1990, Nature.

[62]  L. Gold,et al.  Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. , 1990, Science.

[63]  Eric Westhof,et al.  Solution structure of human U1 snRNA. Derivation of a possible three- dimensional model , 1990, Nucleic Acids Res..

[64]  G. F. Joyce,et al.  Minimum secondary structure requirements for catalytic activity of a self-splicing group I intron. , 1990, Biochemistry.

[65]  J. Tomizawa Control of ColE1 plasmid replication. Intermediates in the binding of RNA I and RNA II. , 1990, Journal of molecular biology.

[66]  C. Pleij,et al.  Pseudoknots: a new motif in the RNA game. , 1990, Trends in biochemical sciences.

[67]  Gerald F. Joyce,et al.  Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA , 1990, Nature.

[68]  D. Lilley,et al.  RNA bulges and the helical periodicity of double-stranded RNA , 1990, Nature.

[69]  E Westhof,et al.  Computer modeling from solution data of spinach chloroplast and of Xenopus laevis somatic and oocyte 5 S rRNAs. , 1989, Journal of molecular biology.

[70]  S. Altman,et al.  Selection and characterization of randomly produced mutants in the gene coding for M1 RNA. , 1988, Journal of molecular biology.

[71]  J. Wells,et al.  Dissecting the catalytic triad of a serine protease , 1988, Nature.

[72]  G. Stormo,et al.  CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[73]  N. Pace,et al.  The secondary structure of ribonuclease P RNA, the catalytic element of a ribonucleoprotein enzyme , 1988, Cell.

[74]  Sung-Hou Kim,et al.  Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[75]  J. Ebel,et al.  Probing the structure of RNAs in solution. , 1987, Nucleic acids research.

[76]  E Westhof,et al.  Crystallographic refinement of yeast aspartic acid transfer RNA. , 1985, Journal of molecular biology.

[77]  Wolfram Saenger,et al.  Principles of Nucleic Acid Structure , 1983 .

[78]  B. Dujon,et al.  Comparison of fungal mitochondrial introns reveals extensive homologies in RNA secondary structure. , 1982, Biochimie.

[79]  P. Sigler An analysis of the structure of tRNA. , 1975, Annual review of biophysics and bioengineering.

[80]  L. Pauling,et al.  The structure of proteins; two hydrogen-bonded helical configurations of the polypeptide chain. , 1951, Proceedings of the National Academy of Sciences of the United States of America.

[81]  T. Cech,et al.  Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus. , 1996, RNA.

[82]  E. Westhof,et al.  The Structure of Group I Ribozymes , 1996 .

[83]  D. Santi,et al.  The catalytic mechanism and structure of thymidylate synthase. , 1995, Annual review of biochemistry.

[84]  R. Gutell,et al.  Representation of the secondary and tertiary structure of group I introns , 1994, Nature Structural Biology.

[85]  Carl R. Woese,et al.  4 Probing RNA Structure, Function, and History by Comparative Analysis , 1993 .

[86]  R. Symons,et al.  Small catalytic RNAs. , 1992, Annual review of biochemistry.

[87]  R. Zwanzig,et al.  Levinthal's paradox. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[88]  G. T. van der Horst,et al.  Reconstitution of a group I intron self-splicing reaction with an activator RNA. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[89]  P. Carbon,et al.  A guide for probing native small nuclear RNA and ribonucleoprotein structures. , 1989, Methods in enzymology.

[90]  L. Gold,et al.  Posttranscriptional regulatory mechanisms in Escherichia coli. , 1988, Annual review of biochemistry.

[91]  B. Ganem RNA world , 1987, Nature.

[92]  W. Saenger tRNA—A Treasury of Stereochemical Information , 1984 .

[93]  S. Arnott The structure of transfer RNA , 1971 .

[94]  C. Levinthal Are there pathways for protein folding , 1968 .