THE PLANT MEDIATED NANOPARTICLES AS A HEALTH PROTECTORS

- While metal nanoparticles are being increasingly used in many sectors of the economy, there is growing interest in the biological and environmental safety of their production. The main methods for nanoparticle production are chemical and physical approaches that are often costly and potentially harmful to the environment. The present review is devoted to the possibility of the biological syntheses of nanoparticles are being carried out by different macro–microscopic organisms such as plant, bacteria, fungi, seaweeds and microalgae. The biosynthesized nanomaterials have been effectively controlling the various endemic diseases with less adverse effect. Plant contains abundant natural compounds such as alkaloids, flavonoids, saponins, steroids, tannins and other nutritional compounds. These natural products are derived from various parts of plant such as leaves, stems, roots shoots, flowers, barks, and seeds. Recently, many studies have proved that the plant extracts act as a potential precursor for the synthesis of nanomaterial in non-hazardous ways. Since the plant extract contains various secondary metabolites, it acts as reducing and stabilizing agents for the bio reduction reaction to synthesized novel metallic nanoparticles. The non-biological methods (chemical and physical) are used in the synthesis of nanoparticles, which has a serious hazardous and high toxicity for living organisms. In addition, the biological synthesis of metallic nanoparticles is inexpensive, single step and eco-friendly methods. The plants are used successfully in the synthesis of various greener nanoparticles such as cobalt, copper, silver, gold, palladium, platinum, zinc oxide and magnetite. Also, the plant mediated nanoparticles are potential remedy for various diseases such as malaria, cancer, HIV, hepatitis and other acute diseases. stem methanolic extract used for synthesis of silver nanoparticles and formed (Callicarpa maingayi)] + complex. The plant extract contains aldehyde group and it’s mainly involved in the reduction of silver ions into metallic Ag nanoparticles. The different functional group C=O and C=N indicates amide I, polypeptides which are the responsible compounds in the capping of ionic substances into metallic nanoparticles. The molecular studies on biosynthesis of silver crystals are complex and not yet fully understood. But some previous studies are proposed model mechanisms of nanoparticles interaction with pathogenic organisms. The biosynthesized silver NPs binding with Protein outer cell wall of bacteria, fungi or viral bodies that breaks the lipoproteins of microbial cell wall. Finally the cell division was stopped and cell leads to death. Photosynthesis of silver nanoparticles use Cissus quadrangular is extracts at room temperature was reported. The stem part of plant extract shows the different functional groups, particularly the carboxyl, amine, and phenolic

[1]  Y. Yun,et al.  Biogenic Synthesis of Metallic Nanoparticles by Plant Extracts , 2013 .

[2]  N. Salem,et al.  Green synthesis of silver nanoparticles using carob leaf extract and its antibacterial activity , 2013, International Journal of Industrial Chemistry.

[3]  D. Philip,et al.  Green synthesis of gold nanoparticles using Trigonella foenum-graecum and its size-dependent catalytic activity. , 2012, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[4]  S. Murugan,et al.  The green synthesis, characterization and evaluation of the biological activities of silver nanoparticles synthesized from Iresine herbstii leaf aqueous extracts. , 2012, Colloids and surfaces. B, Biointerfaces.

[5]  Sam F. Y. Li,et al.  Green synthesis of gold nanoparticles using palm oil mill effluent (POME): a low-cost and eco-friendly viable approach. , 2012, Bioresource technology.

[6]  K. Amarnath,et al.  Synthesis and characterization of chitosan and grape polyphenols stabilized palladium nanoparticles and their antibacterial activity. , 2012, Colloids and surfaces. B, Biointerfaces.

[7]  P. Daisy,et al.  Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus , 2012, International journal of nanomedicine.

[8]  J. Antony,et al.  Comparative evaluation of antibacterial activity of silver nanoparticles synthesized using Rhizophora apiculata and glucose. , 2011, Colloids and surfaces. B, Biointerfaces.

[9]  A. Kumaraguru,et al.  Document heading doi : Biosynthesis of silver nanoparticles by using mangrove plant extract and their potential mosquito larvicidal property , 2011 .

[10]  R. Das,et al.  Green synthesis of gold nanoparticles using Nyctanthes arbortristis flower extract , 2011, Bioprocess and biosystems engineering.

[11]  Mika Sillanpää,et al.  Bioprospective of Sorbus aucuparia leaf extract in development of silver and gold nanocolloids. , 2010, Colloids and surfaces. B, Biointerfaces.

[12]  Ajay Misra,et al.  GREEN SYNTHESIS OF SILVER NANOPARTICLES USING LATEX OF JATROPHA CURCAS , 2009 .

[13]  Dae Hong Jeong,et al.  Antimicrobial effects of silver nanoparticles. , 2007, Nanomedicine : nanotechnology, biology, and medicine.

[14]  Michael Wagener,et al.  An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement. , 2004, Biomaterials.

[15]  Jose R. Peralta-Videa,et al.  Formation and Growth of Au Nanoparticles inside Live Alfalfa Plants , 2002 .

[16]  Durba Das,et al.  Biosynthesized silver nanoparticles by ethanolic extracts of Phytolacca decandra, Gelsemium sempervirens, Hydrastis canadensis and Thuja occidentalis induce differential cytotoxicity through G2/M arrest in A375 cells. , 2013, Colloids and surfaces. B, Biointerfaces.

[17]  J. Bellare,et al.  Dioscorea bulbifera tuber extract and evaluation of its synergistic potential in combination with antimicrobial agents , 2012 .

[18]  Absar Ahmad,et al.  Synthesis of Gold Nanotriangles and Silver Nanoparticles Using Aloevera Plant Extract , 2006, Biotechnology progress.