Improving empirical antibiotic treatment: prospective, nonintervention testing of a decision support system

Leibovici L, Gitelman V, Yehezkelli Y, Poznanski O, Milo G, Paul M & Ein‐dor P (Rabin Medical Centre, Petah‐Tiqva, Sackler Faculty of Medicine, and Faculty of Management, Tel‐Aviv University, Ramat‐Aviv, Tel‐Aviv, Israel). Improving empirical antibiotic treatment: prospective, nonintervention testing of a decision support system. J Intern Med 1997; 242: 395–400.

[1]  H. Lode,et al.  Septicemia in 980 patients at a university hospital in Berlin: prospective studies during 4 selected years between 1979 and 1989. , 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[2]  Katherine Hurlbut.  A simple index to identify occult bacterial infection in adults with acute unexplained fever: Mellors JW, Horwitz RI, Harvey MR, et al Arch Intern Med 147:666–671 Apr 1987 , 1987 .

[3]  L. Leibovici,et al.  Toward improved empiric management of moderate to severe urinary tract infections. , 1992, Archives of internal medicine.

[4]  J. L. Gray,et al.  Antibiotic misuse in two clinical situations: positive blood culture and administration of aminoglycosides. , 1991, Reviews of infectious diseases.

[5]  L. Leibovici,et al.  Patients at risk for inappropriate antibiotic treatment of bacteraemia , 1992, Journal of internal medicine.

[6]  L Leibovici,et al.  Occult bacterial infection in adults with unexplained fever. Validation of a diagnostic index. , 1990, Archives of internal medicine.

[7]  R. Haynes,et al.  Effects of Computer-based Clinical Decision Support Systems on Clinician Performance and Patient Outcome: A Critical Appraisal of Research , 1994, Annals of Internal Medicine.

[8]  C S Bryan,et al.  Analysis of 1,186 episodes of gram-negative bacteremia in non-university hospitals: the effects of antimicrobial therapy. , 1983, Reviews of infectious diseases.

[9]  R. Wenzel,et al.  Long-term survival and function after suspected gram-negative sepsis. , 1995, JAMA.

[10]  I. Phillips,et al.  Clinical index to predict bacteraemia caused by staphylococci , 1993, Journal of internal medicine.

[11]  H A Heathfield,et al.  Philosophies for the Design and Development of Clinical Decision-Support Systems , 1993, Methods of Information in Medicine.

[12]  M R Harvey,et al.  A simple index to identify occult bacterial infection in adults with acute unexplained fever. , 1987, Archives of internal medicine.

[13]  L. Leibovici,et al.  Long-term survival following bacteremia or fungemia. , 1995, JAMA.

[14]  Leonard Leibovici,et al.  Risk factors and a clinical index for diagnosis of Pseudomonas aeruginosa bacteremia. , 1995, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[15]  L. Leibovici,et al.  Bacteremia in febrile patients. A clinical model for diagnosis. , 1991, Archives of internal medicine.

[16]  A. L. Baker,et al.  Performance of four computer-based diagnostic systems. , 1994, The New England journal of medicine.

[17]  M. Fine,et al.  Hospitalization decision in patients with community-acquired pneumonia: a prospective cohort study. , 1990, The American journal of medicine.

[18]  R S Evans,et al.  Improving empiric antibiotic selection using computer decision support. , 1994, Archives of internal medicine.

[19]  David Classen,et al.  Implementing Antibiotic Practice Guidelines through Computer-Assisted Decision Support: Clinical and Financial Outcomes , 1996, Annals of Internal Medicine.

[20]  L. Leibovici,et al.  Predictive index for optimizing empiric treatment of gram-negative bacteremia. , 1991, The Journal of infectious diseases.

[21]  D. Maki,et al.  A study of antimicrobial misuse in a university hospital. , 1978, The American journal of the medical sciences.