Feature analysis in slit-lamp image for nuclear cataract diagnosis

Nuclear cataract is the most common type of age-related cataract and it is clinically diagnosed using slit-lamp images. Objective measurement of the features in slit-lamp image is investigated using a computerized software system. The correlation between the features and the nuclear cataract grades is analyzed. Experimental results show that intensity of sulcus, color in the lens and nucleus region, intensity of nucleus, and color in posterior reflex region are the key features for grading nuclear cataract. This study of feature analysis can benefit clinical cataract diagnosis and clinical research. The feature analysis can also be utilized to investigate the performance of different graders and be employed in training of new graders.

[1]  Joo-Hwee Lim,et al.  A Computer-Aided Diagnosis System of Nuclear Cataract , 2010, IEEE Transactions on Biomedical Engineering.

[2]  K L Linton,et al.  Assessment of cataracts from photographs in the Beaver Dam Eye Study. , 1990, Ophthalmology.

[3]  T. Wong,et al.  Rationale and Methodology for a Population-Based Study of Eye Diseases in Malay People: The Singapore Malay Eye Study (SiMES) , 2007, Ophthalmic epidemiology.

[4]  M. C. Leske,et al.  The Lens Opacities Classification System III , 1993 .

[5]  P. Cochat,et al.  Et al , 2008, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[6]  Charles R. Dyer,et al.  An Automatic System for Classification of Nuclear Sclerosis from Slit-Lamp Photographs , 2003, MICCAI.

[7]  D D Duncan,et al.  New objective classification system for nuclear opacification. , 1997, Journal of the Optical Society of America. A, Optics, image science, and vision.

[8]  P. Asbell,et al.  Age-related cataract , 2005, The Lancet.

[9]  Huiqi Li,et al.  Boundary detection of optic disk by a modified ASM method , 2003, Pattern Recognit..

[10]  A. R. Hill,et al.  The Oxford Clinical Cataract Classification and Grading System , 1986, International Ophthalmology.

[11]  Allen Foster,et al.  Vision 2020 – the Right to Sight , 2003, Tropical doctor.