Regional and Distant Metastases in Laryngeal and Hypopharyngeal Sarcomas

Cervical node and distant metastases are the most important prognostic factors in malignant laryngeal neoplasms. Owing to the unusual occurrence of laryngeal sarcomas, the prevalence of their metastases has never been analyzed in detail. We reviewed the laryngeal sarcomas reported in the literature and noticed that both regional and distant metastases are rare events and variable for different histotypes. These observations have obvious therapeutic and prognostic implications.

[1]  H. Glanz,et al.  Myogenic tumours of the larynx , 2004, Archives of oto-rhino-laryngology.

[2]  J. Skandalakis,et al.  Tumors of the Oral Cavity and Pharynx , 2000, World Journal of Surgery.

[3]  S. Shapshay,et al.  Kaposi's Sarcoma of the Larynx , 1997, The Annals of otology, rhinology, and laryngology.

[4]  D. MoraisPérez,et al.  Malignant fibrohistiocytoma in otorhinolaryngology. Review of two cases , 1997 .

[5]  K. Olsen,et al.  Cartilaginous Tumors of the Larynx: Clinicopathologic Review of 47 Cases , 1997, The Annals of otology, rhinology, and laryngology.

[6]  C. T. Wu,et al.  Postirradiation laryngeal osteosarcoma: Case report and literature review , 1997, Head & neck.

[7]  J. Werner,et al.  Das Chondrosarkom des Kehlkopfes , 1997 .

[8]  P. Dalla Palma,et al.  [Laryngeal malignant schwannoma in a 9-year-old boy: report of a clinical case]. , 1996, Pathologica.

[9]  P. Colloby,et al.  Malignant fibrous histiocytomas of the larynx--report of two cases. , 1996, Annals of the Academy of Medicine, Singapore.

[10]  R. Miller,et al.  Laryngeal Kaposi's sarcoma in patients with AIDS , 1996, The Journal of Laryngology & Otology.

[11]  A. Benider,et al.  [Leiomyosarcoma of the larynx. Review of the literature apropos of a case]. , 1996, Bulletin du cancer.

[12]  M. C. da Mosto,et al.  Laryngeal Pleomorphic Rhabdomyosarcoma a Critical Review of the Literature , 1996, The Annals of otology, rhinology, and laryngology.

[13]  T. Venkatesan,et al.  Intralesional Vinblastine for Treating Aids-Associated Kaposi's Sarcoma of the Oropharynx and Larynx , 1996, The Annals of otology, rhinology, and laryngology.

[14]  J. Reed,et al.  Hypopharyngeal Liposarcoma , 1996, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[15]  S. Sahraoui,et al.  Polychimiothérapie préradiothérapique dans les carcinomes du cavum. Expérience du centre d'oncologie Ibn Rochd — Casablanca , 1996 .

[16]  J. Verhulst,et al.  Les chondromes et chondrosarcome du larynx : à propos de 4 observations , 1996 .

[17]  B. Wenig,et al.  Liposarcomas of the larynx and hypopharynx: A clinicopathologic study of eight new cases and a review of the literature , 1995, The Laryngoscope.

[18]  G. Fichera.  [Pleomorphic storiform malignant fibrohistiocytoma of the larynx. Case report and anatomo-clinical considerations]. , 1995, Pathologica.

[19]  G. Fichera,et al.  [A rare mesenchymal tumor of the larynx . Case report and anatomo-clinical features]. , 1995, Pathologica.

[20]  R. Weber,et al.  Synovialzellsarkome im Kopf- und Halsbereich , 1995 .

[21]  V. Desmet,et al.  Angiosarcoma of the larynx , 1995, Histopathology.

[22]  H. Chapuis,et al.  [Malignant histiocytofibroma. Apropos of 3 cases of cervicofacial localization]. , 1995, Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris.

[23]  J. Elidan,et al.  Fibrosacroma of the vocal fold: a late complication of radiotherapy , 1994, The Journal of Laryngology & Otology.

[24]  M. Krengli,et al.  Angiosarcoma of the hypopharynx , 1994, The Journal of Laryngology & Otology.

[25]  G. Healy,et al.  Malignant Laryngeal Tumors in Children: A 15-Year Experience with Four Patients , 1994, The Annals of otology, rhinology, and laryngology.

[26]  Stefano Sellari-Franceschini,et al.  Léiomyosarcome du larynx: revue de littérature, à propos d'un cas , 1994 .

[27]  T. Vogl,et al.  Nicht-plattenepitheliale Malignome des Larynx unter besonderer Berücksichtigung der MRT-Diagnostik , 1994 .

[28]  R. Gertner,et al.  Laryngeal liposarcoma. , 2020, Archives of otolaryngology--head & neck surgery.

[29]  M. Nakayama,et al.  Dedifferentiated Chondrosarcoma of the Larynx with Regional and Distant Metastases , 1993, The Annals of otology, rhinology, and laryngology.

[30]  C. A. Morán,et al.  Laryngeal chondrosarcomas. , 1993, Archives of pathology & laboratory medicine.

[31]  K. Olsen,et al.  Head and Neck Synovial Cell Sarcoma , 1992, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[32]  American Academy of Otolaryngology-Head and Neck Surgery, Inc. , 1992 .

[33]  P. Som,et al.  Laryngeal chondrosarcomas: A clinicopathologic study of 11 cases, including two “dedifferentiated” chondrosarcomas , 1992, The Laryngoscope.

[34]  A. Darré,et al.  Une tumeur exceptionnelle du larynx : l'histiocytome fibreux malin : à propos d'une observation et revue de la littérature , 1992 .

[35]  D. Glaubiger,et al.  Chondrosarcoma of the larynx after radiation treatment for vocal cord cancer , 1991, Cancer.

[36]  J. Skladzien,et al.  [Non-epithelial malignant neoplasms of the larynx]. , 1991, Otolaryngologia polska = The Polish otolaryngology.

[37]  D. Gatland,et al.  Malignant Transformation in a Laryngeal Hemangioma , 1990, The Annals of otology, rhinology, and laryngology.

[38]  O. Kawashima,et al.  Malignant mesenchymoma of the larynx , 1990, The Journal of Laryngology & Otology.

[39]  J. Pinsolle,et al.  Osteosarcoma of the soft tissue of the larynx: Report of a case with electron microscopic studies , 1990, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[40]  J. Strauchen,et al.  Atypical granular cell tumor of the larynx: An unusually aggressive tumor clinically and microscopically , 1990, Head & neck.

[41]  K. Makino,et al.  Malignant fibrous histiocytoma of the hypopharynx. , 1990, ORL; journal for oto-rhino-laryngology and its related specialties.

[42]  A. Ferlito.  Laryngeal fibrosarcoma: an over-diagnosed tumor. , 1990, ORL; journal for oto-rhino-laryngology and its related specialties.

[43]  C. Stayboldt,et al.  Chondrosarcoma of the epiglottis with regional and distant metastasis , 1989, The Laryngoscope.

[44]  J. Boss,et al.  Liposarcoma of the larynx , 1988, The Journal of Laryngology & Otology.

[45]  D. A. Tandon,et al.  Embryonal rhabdomyosarcoma of the larynx in a child: report of a case and review of literature. , 1988, Indian journal of cancer.

[46]  D. G. John,et al.  Chondrosarcoma of the epiglottis , 1988, The Journal of Laryngology & Otology.

[47]  R. Stanley,et al.  Neural and Neuroendocrine Tumors of the Larynx , 1987, The Annals of otology, rhinology, and laryngology.

[48]  A. El-Mahdi,et al.  Alveolar rhabdomyosarcoma of the larynx: Case report and literature review , 1987, The Laryngoscope.

[49]  G. Berke,et al.  Synovial sarcoma of the head and neck. , 1987, Archives of otolaryngology--head & neck surgery.

[50]  H. Levine,et al.  Nonsquamous neoplasms of the larynx. , 1986, Otolaryngologic clinics of North America.

[51]  V. Vital,et al.  Angiosarcoma of the hypopharynx--a case report. , 1985, Pathology, research and practice.

[52]  A. Jefferis,et al.  Squamous cell carcinoma and liposarcoma of the larynx occurring metachronously , 1985, The Journal of Laryngology & Otology.

[53]  J. D. Harmon,et al.  Liposarcoma of the larynx. , 1985, Archives of pathology & laboratory medicine.

[54]  B. Oppedal,et al.  Synovial sarcomas of the neck A report of two cases , 1985, The Journal of Laryngology & Otology.

[55]  H. Nordlinder,et al.  Benign pedunculated tumours of the hypopharynx. 3 case reports, 1 with late malignant transformation. , 1985, ORL; journal for oto-rhino-laryngology and its related specialties.

[56]  A. Ferlito,et al.  Chondrosarcoma of the larynx: review of the literature and report of three cases. , 1984, American journal of otolaryngology.

[57]  A. Escher,et al.  [Clinical aspects and pathology of chondromatous tumors of the larynx]. , 1984, HNO.

[58]  F. Escher,et al.  Zur Klinik und Pathologie chondromatöser Tumoren des Larynx , 1984 .

[59]  F. F. F. D. L. Michaels MD.  Pathology of the Larynx , 1984, Springer London.

[60]  A. Ferlito,et al.  Primary Laryngeal Malignant Fibrous Histiocytoma: Review of the Literature and Report of Seven Cases , 1983, The Laryngoscope.

[61]  C. Abramowsky,et al.  Sarcoma of the larynx in a newborn , 1983, Cancer.

[62]  U. Hacihanefioğlu,et al.  Sarcomas of the Larynx , 1983, The Annals of otology, rhinology, and laryngology.

[63]  H. DeLozier.  Intrinsic Malignant Schwannoma of the Larynx , 1982, The Annals of otology, rhinology, and laryngology.

[64]  K. Unni,et al.  Cartilaginous Tumors of the Larynx: A Series of 33 Patients , 1982, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[65]  L. Neblett,et al.  Malignant fibrous histiocytoma of the larynx. , 1981, American journal of otolaryngology.

[66]  A. Harwood,et al.  Radiotherapy of chondrosarcoma of bone , 1980, Cancer.

[67]  R. Dietz,et al.  Primäre maligne mesenchymale Tumoren im Kopf-Hals-Bereich , 1980 .

[68]  R. Dietz,et al.  Diagnostik und Therapie seltener Tumoren im Larynx-Pharynx-Bereich* , 1980 .

[69]  M. V. Seniukov,et al.  [Rhabdomyosarcoma of the larynx]. , 1979, Vestnik otorinolaringologii.

[70]  F. Vellios,et al.  Osteosarcoma of the soft tissue of the larynx. Report of a case with light and electron microscopic studies , 1978, Cancer.

[71]  A. Ferlito.  Histiocytic tumors of the larynx. A clinicopathological study with review of the literature , 1978, Cancer.

[72]  A. Chaudhry,et al.  Chondroblastic osteosarcoma of the larynx. , 1978, Archives of otolaryngology.

[73]  M. Lorentzen,et al.  Rhabdomyosarcoma of the larynx , 1978, The Journal of Laryngology & Otology.

[74]  G. Spector,et al.  Liposarcoma of the larynx: A multicentric or a metastatic malignancy , 1977, The Laryngoscope.

[75]  A. Ferlito,et al.  Pleomorphic rhabdomyosarcoma of the larynx , 1976, The Journal of Laryngology & Otology.

[76]  Lockey Mw.  Rare tumors of the ear, nose and throat: synovial sarcoma of the head and neck. , 1976 .

[77]  J. E. Freeman,et al.  Radiotherapy and adjuvant combination chemotherapy for childhood rhabdomyosarcoma. , 1976, British medical journal.

[78]  C. G. Strom,et al.  Synovial sarcoma of the laryngopharynx. , 1975, Archives of otolaryngology.

[79]  F. Enzinger,et al.  Synovial sarcoma of the neck: A followup study of 24 cases , 1975, Cancer.

[80]  F. Hirose,et al.  Malignant fibrous xanthoma (xanthofibrosarcoma) of the larynx. , 1975, Archives of otolaryngology.

[81]  D. S. Cameron,et al.  Osteosarcoma of the larynx , 1973, The Journal of Laryngology & Otology.

[82]  S. Suwansirikul,et al.  Rhabdomyosarcoma producing respiratory obstruction. , 1971, JAMA.

[83]  K. Balogh,et al.  Cartilaginous tumors of the larynx A clinicopathologic study of 10 new cases and a review of the literature , 1970, Cancer.

[84]  V. Hyams,et al.  Cartilaginous tumors of the larynx , 1970, The Laryngoscope.

[85]  T. Al-Saleem,et al.  Cartilaginous tumors of the larynx. Clinical-pathologic study of ten cases. , 1970, Annals of Otology, Rhinology and Laryngology.

[86]  E. Degowin,et al.  Laryngeal chondrosarcoma after thyroid irradiation. , 1969, JAMA.

[87]  L. W. Pratt,et al.  Hemangioendotheliosarcoma of the larynx. , 1968, Archives of otolaryngology.

[88]  T. Kondo,et al.  [Laryngeal leiomyosarcoma--evaluation of the authors' case and observation of the literature]. , 1967, Jibi inkoka Otolaryngology.

[89]  C. Norris,et al.  Sarcoma of the larynx , 1961, Transactions of the ... annual meeting of the American Laryngological Association. American Laryngological Association. Annual Meeting.

[90]  C. Norris,et al.  LXVII Sarcoma of the Larynx , 1961 .

[91]  Stout Ap.  Tumors featuring pericytes; glomus tumor and hemangiopericytoma. , 1956 .

[92]  P. Jernstrom.  Synovial sarcoma of the pharynx; report of a case. , 1954, American journal of clinical pathology.

[93]  H. Sirota,et al.  Chondrosarcoma of the larynx. , 1952, A.M.A. archives of otolaryngology.

[94]  L. Clerf.  Sarcoma of the larynx; report of eight cases. , 1946, Archives of otolaryngology.

[95]  Mcculloch.  Diseases and injuries of the larynx , 1942 .

[96]  D. I. Frank.  LEIOMYOSARCOMA OF THE LARYNX: REPORT OF A CASE , 1941 .

[97]  F. A. Figi.  SARCOMA OF THE LARYNX , 1933 .