Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.

[1]  M. Linton,et al.  Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice DOI 10.1194/jlr.M200108-JLR200 , 2002, Journal of Lipid Research.

[2]  A. Lusis,et al.  Atherosclerosis in C3H/HeJ Mice Reconstituted With Apolipoprotein E-Null Bone Marrow , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[3]  D. Rader,et al.  Reduction of Isoprostanes and Regression of Advanced Atherosclerosis by Apolipoprotein E* , 2001, The Journal of Biological Chemistry.

[4]  A. Lusis,et al.  Effect of Macrophage-Derived Apolipoprotein E on Established Atherosclerosis in Apolipoprotein E–Deficient Mice , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[5]  D. Rader,et al.  Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in mice. , 2000, Journal of lipid research.

[6]  T. V. van Berkel,et al.  Accelerated atherosclerosis in C57Bl/6 mice transplanted with ApoE-deficient bone marrow. , 2000, Atherosclerosis.

[7]  D. Rader,et al.  Rapid regression of atherosclerosis induced by liver-directed gene transfer of ApoE in ApoE-deficient mice. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[8]  M. Linton,et al.  Determination of the lower threshold of apolipoprotein E resulting in remnant lipoprotein clearance. , 1999, Journal of lipid research.

[9]  L. Curtiss,et al.  Elimination of macrophage-specific apolipoprotein E reduces diet-induced atherosclerosis in C57BL/6J male mice. , 1999, Journal of lipid research.

[10]  M. Ferguson,et al.  Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: colocalization of biglycan with apolipoproteins. , 1998, Circulation.

[11]  T. J. Berkel,et al.  Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E- deficient mouse hepatocytes. , 1997, The Journal of clinical investigation.

[12]  T. V. van Berkel,et al.  Bone marrow transplantation in apolipoprotein E-deficient mice. Effect of ApoE gene dosage on serum lipid concentrations, (beta)VLDL catabolism, and atherosclerosis. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[13]  M. Linton,et al.  Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[14]  M. Tremblay,et al.  Characterization of human plasma apolipoprotein E-containing lipoproteins in the high density lipoprotein size range: focus on pre-beta1-LpE, pre-beta2-LpE, and alpha-LpE. , 1997, Journal of lipid research.

[15]  U. Beisiegel Receptors for triglyceride-rich lipoproteins and their role in lipoprotein metabolism , 1995, Current opinion in lipidology.

[16]  S. Fazio,et al.  Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation , 1995, Science.

[17]  T. Drake,et al.  Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification. , 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

[18]  T. Mazzone,et al.  Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3. , 1994, Journal of lipid research.

[19]  J. Taylor,et al.  Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture. , 1994, The Journal of biological chemistry.

[20]  D K Burns,et al.  Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. , 1994, The Journal of clinical investigation.

[21]  A. Lusis,et al.  Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice. , 1993, The Journal of biological chemistry.

[22]  N. Maeda,et al.  Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. , 1992, Science.

[23]  E. Rubin,et al.  Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells , 1992, Cell.

[24]  D. Pardoll,et al.  Lymphoid reconstitution after transplantation of congenic hematopoietic cells in busulfan-treated mice. , 1991, Blood.

[25]  R. Mahley,et al.  Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. , 1988, Science.

[26]  P. Dawson,et al.  Synthesis of Apolipoprotein E by Peripheral Tissues , 1985 .

[27]  C. L. Jackson,et al.  Distribution of apolipoprotein A-I, C-II, C-III, and E mRNA in fetal human tissues. Time-dependent induction of apolipoprotein E mRNA by cultures of human monocyte-macrophages. , 1985, Biochemistry.

[28]  G. Getz,et al.  Extrahepatic synthesis of apolipoprotein E. , 1984, Journal of lipid research.

[29]  D. Longo,et al.  Early appearance of donor-type antigen-presenting cells in the thymuses of 1200 R radiation-induced bone marrow chimeras correlates with self-recognition of donor I region gene products. , 1983, Journal of immunology.

[30]  M. Brown,et al.  Independent pathways for secretion of cholesterol and apolipoprotein E by macrophages. , 1983, Science.

[31]  E. Schaefer,et al.  Type III hyperlipoproteinemia associated with apolipoprotein E deficiency. , 1981, Science.

[32]  P. Nilsson-ehle,et al.  A stable, radioactive substrate emulsion for assay of lipoprotein lipase. , 1976, Journal of lipid research.

[33]  S. Otway,et al.  The use of a non‐ionic detergent (Triton WR 1339) to determine rates of triglyceride entry into the circulation of the rat under different physiological conditions , 1967, The Journal of physiology.