The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?
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[1] J. Nesland,et al. Snail, Slug, and Smad‐interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma , 2005, Cancer.
[2] J. Zhang,et al. miR-200bc/429 cluster targets PLCγ1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer , 2010, Oncogene.
[3] Patricia Greninger,et al. A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival. , 2009, Cancer cell.
[4] A. Osunkoya,et al. Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells , 2009, Breast Cancer Research and Treatment.
[5] Meenakshi Singh,et al. ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease , 2008, Modern Pathology.
[6] Sun-Mi Park,et al. miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1. , 2010, Molecular cell.
[7] F. Slack,et al. Oncomirs — microRNAs with a role in cancer , 2006, Nature Reviews Cancer.
[8] A. Osunkoya,et al. Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells. , 2008, Cancer research.
[9] W. L. Ruzzo,et al. MicroRNA Discovery and Profiling in Human Embryonic Stem Cells by Deep Sequencing of Small RNA Libraries , 2008, Stem cells.
[10] B. Davidson,et al. Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions , 2010, Clinical & Experimental Metastasis.
[11] T. Brabletz,et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells , 2008, EMBO reports.
[12] D. McConkey,et al. Delta-Crystallin Enhancer Binding Factor 1 Controls the Epithelial to Mesenchymal Transition Phenotype and Resistance to the Epidermal Growth Factor Receptor Inhibitor Erlotinib in Human Head and Neck Squamous Cell Carcinoma Lines , 2009, Clinical Cancer Research.
[13] Julia Schüler,et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs , 2009, Nature Cell Biology.
[14] Woonyoung Choi,et al. miR-200 Expression Regulates Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Reverses Resistance to Epidermal Growth Factor Receptor Therapy , 2009, Clinical Cancer Research.
[15] Marina Kriajevska,et al. SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer , 2009, Proceedings of the National Academy of Sciences.
[16] Jae Hoon Kim,et al. MicroRNA Expression Profiles in Serous Ovarian Carcinoma , 2008, Clinical Cancer Research.
[17] I. Fabregat,et al. Snail blocks the cell cycle and confers resistance to cell death. , 2004, Genes & development.
[18] Birgit Luber,et al. Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. , 2002, The American journal of pathology.
[19] G. Berx,et al. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. , 2001, Molecular cell.
[20] A. Puisieux,et al. Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition , 2008, PloS one.
[21] M. Nieto,et al. Inflammation and EMT: an alliance towards organ fibrosis and cancer progression , 2009, EMBO molecular medicine.
[22] T. Gress,et al. Collagen type I-induced Smad-interacting protein 1 expression downregulates E-cadherin in pancreatic cancer , 2007, Oncogene.
[23] E. Howe,et al. Loss of miR-200c: A Marker of Aggressiveness and Chemoresistance in Female Reproductive Cancers , 2009, Journal of oncology.
[24] I. Pogribny,et al. E‐cadherin transcriptional down‐regulation by epigenetic and microRNA‐200 family alterations is related to mesenchymal and drug‐resistant phenotypes in human breast cancer cells , 2010, International journal of cancer.
[25] R. Cameron,et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. , 2006, Cancer research.
[26] Tatyana Chernova,et al. Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. , 2007, Molecular biology of the cell.
[27] E. Hurt,et al. Expression of the ZEB1 (δEF1) transcription factor in human: additional insights , 2008, Molecular and Cellular Biochemistry.
[28] G. Browne,et al. ZEB proteins link cell motility with cell cycle control and cell survival in cancer , 2010, Cell cycle.
[29] L. Buscail,et al. MicroRNA-21 is induced early in pancreatic ductal adenocarcinoma precursor lesions. , 2010, Clinical chemistry.
[30] V. Kim,et al. Conserved MicroRNA miR-8/miR-200 and Its Target USH/FOG2 Control Growth by Regulating PI3K , 2009, Cell.
[31] O. Kent,et al. A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells , 2009, Cancer biology & therapy.
[32] S. Elledge,et al. Multiple Tumor Suppressor Pathways Negatively Regulate Telomerase , 2003, Cell.
[33] M. Peter. Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression , 2009, Cell cycle.
[34] Zhihui Feng,et al. A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer. , 2009, Gynecologic oncology.
[35] R. Maestro,et al. Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. , 2008, Cancer cell.
[36] G. Gallick,et al. Development and Characterization of Gemcitabine-Resistant Pancreatic Tumor Cells , 2007, Annals of Surgical Oncology.
[37] Cameron P Bracken,et al. MicroRNAs as regulators of epithelial-mesenchymal transition , 2008, Cell cycle.
[38] Zhiwei Wang,et al. Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. , 2009, Cancer research.
[39] Huamin Wang,et al. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. , 2009, Cancer research.
[40] Sun-Mi Park,et al. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. , 2008, Genes & development.
[41] Raghu Kalluri,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[42] Laura Pelletier,et al. MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations , 2008, Hepatology.
[43] Kevin Struhl,et al. MicroRNAs Differentially Regulated by Akt Isoforms Control EMT and Stem Cell Renewal in Cancer Cells , 2009, Science Signaling.
[44] Jun Du,et al. BMP-6 inhibits microRNA-21 expression in breast cancer through repressing δEF1 and AP-1 , 2009, Cell Research.
[45] R. Foisner,et al. The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity , 2007, Oncogene.
[46] A. Postigo,et al. ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1 , 2010, Oncogene.
[47] T. Sjöblom,et al. Sustained TGFβ exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis , 2007, Oncogene.
[48] Wen-juan Wang,et al. Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells , 2009, Clinical Cancer Research.
[49] K. Horwitz,et al. The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers. , 2006, Cancer research.
[50] E. Bellefroid,et al. δEF1 and SIP1 are differentially expressed and have overlapping activities during Xenopus embryogenesis , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.
[51] R. Huang,et al. Epithelial-Mesenchymal Transitions in Development and Disease , 2009, Cell.
[52] G. Berx,et al. The role of the ZEB family of transcription factors in development and disease , 2009, Cellular and Molecular Life Sciences.
[53] R. Knuechel,et al. Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[54] Douglas S. Darling,et al. Zeb1 links epithelial-mesenchymal transition and cellular senescence , 2008, Development.
[55] J. Lieberman,et al. miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases , 2009, PloS one.
[56] M. Herlyn,et al. Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors. , 2010, Cancer research.
[57] H. Zhang,et al. MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer. , 2009, Genes & development.
[58] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[59] M. Zhou,et al. microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network. , 2010, Carcinogenesis.
[60] G. Goodall,et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1 , 2008, Nature Cell Biology.
[61] M. F. Shannon,et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. , 2008, Cancer research.
[62] K. Sossey-Alaoui,et al. The miR200 Family of MicroRNAs Regulates WAVE3-dependent Cancer Cell Invasion* , 2009, The Journal of Biological Chemistry.
[63] Alexander Pertsemlidis,et al. Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. , 2009, Genes & development.
[64] Héctor Peinado,et al. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? , 2007, Nature Reviews Cancer.
[65] I. Gérin,et al. The microRNA miR-8 is a conserved negative regulator of Wnt signaling , 2008, Proceedings of the National Academy of Sciences.
[66] S. Spivack,et al. Overexpression of the microRNA hsa-miR-200c leads to reduced expression of transcription factor 8 and increased expression of E-cadherin. , 2007, Cancer research.
[67] Asli Silahtaroglu,et al. miR-200b mediates post-transcriptional repression of ZFHX1B. , 2007, RNA.
[68] J. Haley,et al. Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition , 2007, Molecular Cancer Therapeutics.
[69] R. Figlin,et al. Tumor Response to Combination Celecoxib and Erlotinib Therapy in Non-small Cell Lung Cancer Is Associated with a Low Baseline Matrix Metalloproteinase-9 and a Decline in Serum-Soluble E-Cadherin , 2008, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[70] T. Sjöblom,et al. Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis. , 2008, Oncogene.
[71] J. Minna,et al. Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. , 2006, Cancer research.
[72] Wenjun Guo,et al. The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.
[73] Yoshihiro Adachi,et al. Zeb1‐mediated T‐cadherin repression increases the invasive potential of gallbladder cancer , 2009, FEBS letters.
[74] B. Karlan,et al. Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition. , 2010, Gynecologic oncology.
[75] Thomas Kirchner,et al. Migrating cancer stem cells — an integrated concept of malignant tumour progression , 2005, Nature Reviews Cancer.
[76] A. Postigo,et al. Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins , 2003, The EMBO journal.
[77] G. Berx,et al. A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer. , 2006, Gastroenterology.
[78] G. Niedobitek,et al. The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. , 2001, The American journal of pathology.
[79] Thomas Kirchner,et al. Invasion and Metastasis in Colorectal Cancer: Epithelial-Mesenchymal Transition, Mesenchymal-Epithelial Transition, Stem Cells and β-Catenin , 2005, Cells Tissues Organs.
[80] Zhiwei Wang,et al. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. , 2009, Cancer research.
[81] Michael F. Clarke,et al. Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells , 2009, Cell.
[82] X. Bian,et al. miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion. , 2010, Biochemical and biophysical research communications.
[83] A. Regev,et al. An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors , 2008, Nature Genetics.
[84] A. Dimmler,et al. The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. , 2008, Cancer research.
[85] M. Korpal,et al. The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2* , 2008, Journal of Biological Chemistry.