5-(4-Fluorophenyl)-2,6-dioxo-2,3,6,7,8,9-hexahydro-1H,5H-imidazo[1,2-a]quinoline-4-carbonitrile
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In the molecule of the title compound, C18H14FN3O2, the imidazole and dihydropyridine rings are nearly coplanar with a dihedral angle of 2.46 (3)°, while the cyclohexene ring has an envelope conformation. The benzene ring is oriented with respect to the coplanar ring system at a dihedral angle of 81.45 (2)°. In the crystal structure, intermolecular N—H⋯N hydrogen bonds link the molecules into dimers.
[1] E. De Clercq,et al. Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents. , 1996, Journal of medicinal chemistry.
[2] D. Cremer,et al. General definition of ring puckering coordinates , 1975 .