Analysis of HHV-6 mutations in solid organ transplant recipients at the onset of cytomegalovirus disease and following treatment with intravenous ganciclovir or oral valganciclovir.

[1]  N. J. Knowles,et al.  Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2015) , 2009, Archives of Virology.

[2]  G. Boivin,et al.  Evaluation of Epstein-Barr Virus, Human Herpesvirus 6 (HHV-6), and HHV-8 Antiviral Drug Susceptibilities by Use of Real-Time-PCR-Based Assays , 2013, Journal of Clinical Microbiology.

[3]  K. Ozono,et al.  Complementation of the Function of Glycoprotein H of Human Herpesvirus 6 Variant A by Glycoprotein H of Variant B in the Virus Life Cycle , 2012, Journal of Virology.

[4]  H. Agut,et al.  Chromosomally integrated human herpesvirus 6: questions and answers , 2011, Reviews in medical virology.

[5]  K. Baldwin Ganciclovir-resistant human herpesvirus-6 encephalitis in a liver transplant patient: a case report , 2011, Journal of NeuroVirology.

[6]  S. Chou,et al.  Antiviral Drug Resistance of Human Cytomegalovirus , 2010, Clinical Microbiology Reviews.

[7]  N. Frenkel,et al.  Cloning human herpes virus 6A genome into bacterial artificial chromosomes and study of DNA replication intermediates , 2009, Proceedings of the National Academy of Sciences.

[8]  Y. Isegawa,et al.  Detection and identification of U69 gene mutations encoded by ganciclovir-resistant human herpesvirus 6 using denaturing high-performance liquid chromatography. , 2009, Journal of virological methods.

[9]  A. Åsberg,et al.  Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir , 2009, Antiviral therapy.

[10]  A. Åsberg,et al.  Long‐Term Outcomes of CMV Disease Treatment with Valganciclovir Versus IV Ganciclovir in Solid Organ Transplant Recipients , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[11]  H. Rollag,et al.  An Assessment of Herpesvirus Co‐infections in Patients with CMV Disease: Correlation with Clinical and Virologic Outcomes , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[12]  R. Fukunaga,et al.  Human herpesvirus 6 ganciclovir-resistant strain with amino acid substitutions associated with the death of an allogeneic stem cell transplant recipient. , 2009, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[13]  H Rollag,et al.  Oral Valganciclovir Is Noninferior to Intravenous Ganciclovir for the Treatment of Cytomegalovirus Disease in Solid Organ Transplant Recipients , 2007, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[14]  H. Agut,et al.  Human herpesvirus-6 (HHV-6) DNA in plasma reflects the presence of infected blood cells rather than circulating viral particles. , 2007, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[15]  O. Lyytikäinen,et al.  HHV‐6 and HHV‐7 antigenemia related to CMV infection after liver transplantation , 2006, Journal of medical virology.

[16]  A. Humar,et al.  American Society of Transplantation Recommendations for Screening, Monitoring and Reporting of Infectious Complications in Immunosuppression Trials in Recipients of Organ Transplantation , 2006, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[17]  L. Naesens,et al.  Therapeutic Approaches to HHV-6 Infection , 2006 .

[18]  E. De Clercq,et al.  Update on Human Herpesvirus 6 Biology, Clinical Features, and Therapy , 2005, Clinical Microbiology Reviews.

[19]  D. Safronetz,et al.  Mapping ganciclovir resistance in the human herpesvirus‐6 U69 protein kinase , 2003, Journal of medical virology.

[20]  Thomas F. Smith,et al.  Detection of simultaneous β‐herpesvirus infections in clinical syndromes due to defined cytomegalovirus infection , 2003, Clinical transplantation.

[21]  C. Manichanh,et al.  Development of a real-time polymerase chain reaction assay for the diagnosis of human herpesvirus-6 infection and application to bone marrow transplant patients. , 2002, Journal of virological methods.

[22]  C. Manichanh,et al.  Selection of the same mutation in the U69 protein kinase gene of human herpesvirus-6 after prolonged exposure to ganciclovir in vitro and in vivo. , 2001, The Journal of general virology.

[23]  D. Snydman,et al.  Association of human herpesvirus 6 reactivation with severe cytomegalovirus-associated disease in orthotopic liver transplant recipients. , 2001, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[24]  Thomas F. Smith,et al.  Human β-Herpesvirus Interactions in Solid Organ Transplant Recipients , 2001 .

[25]  V. Emery,et al.  The U69 Gene of Human Herpesvirus 6 Encodes a Protein Kinase Which Can Confer Ganciclovir Sensitivity to Baculoviruses , 1999, Journal of Virology.

[26]  D. Snydman,et al.  Human herpesvirus 6 reactivation is associated with cytomegalovirus infection and syndromes in kidney transplant recipients at risk for primary cytomegalovirus infection. , 1998, The Journal of infectious diseases.

[27]  D. Coen,et al.  A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells , 1992, Nature.

[28]  M. Chee,et al.  Human cytomegalovirus UL97 open reading frame encodes a protein that phosphorylates the antiviral nucleoside analogue ganciclovir , 1992, Nature.

[29]  T. Spector,et al.  Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate. , 1989, The Journal of biological chemistry.