Ultra-high resolution millimeter-wave imaging for biomedical applications: Feasibility study

This article numerically verifies ultra-high-resolution confocal millimeter-wave imaging for biomedical applications for the first time. A system with an ultra-wide bandwidth of more than 85 GHz is proposed to provide the ultra-high resolutions required for biomedical imaging applications. The feasibility of detecting early-stage tumors in three dimensions is shown using realistic numerical phantoms. A suitable image formation algorithm is developed and applied to the data. Successful resolution of spherical tumors is achieved in the obtained images both axially and laterally.

[1]  Negar Tavassolian,et al.  Synthetic ultra-wideband antenna for high-resolution millimeter-wave imaging , 2015, 2015 IEEE International Symposium on Antennas and Propagation & USNC/URSI National Radio Science Meeting.

[2]  K. Foster,et al.  Microwave dielectric properties of tissue. Some comments on the rotational mobility of tissue water. , 1977, Biophysical journal.

[3]  M C Ziskin,et al.  Millimeter wave dosimetry of human skin , 2008, Bioelectromagnetics.

[4]  Weng Cho Chew,et al.  Experimental verification of super resolution in nonlinear inverse scattering , 1998 .

[5]  D. W. van der Weide,et al.  Microwave imaging via space-time beamforming: experimental investigation of tumor detection in multilayer breast phantoms , 2004, IEEE Transactions on Microwave Theory and Techniques.

[6]  Amin M. Abbosh,et al.  Synthetic Bandwidth Radar for Ultra-Wideband Microwave Imaging Systems , 2014, IEEE Transactions on Antennas and Propagation.

[7]  Thomas E. Hall,et al.  Three-dimensional millimeter-wave imaging for concealed weapon detection , 2001 .

[8]  O. Gandhi,et al.  Absorption of Millimeter Waves by Human Beings and its Biological Implications , 1986 .

[9]  Adriaan van den Bos,et al.  Resolution: a survey , 1997 .

[10]  Anna N Yaroslavsky,et al.  Continuous wave terahertz transmission imaging of nonmelanoma skin cancers , 2011, Lasers in surgery and medicine.

[11]  L. Zon,et al.  Melanocytes in development and cancer , 2010, Journal of cellular physiology.