Protonation equilibria of glycylglycine and histamine in aqueous solution of an anionic surfactant

Abstract The protonation constants of glycylglycine and histamine are studied in sodium lauryl sulfate–water mixtures (0.5–2.5% w/v) at 303.0 ± 0.1 K at an ionic strength of 0.16 M using a pH-metric technique. The protonation constants are calculated with the computer program MINIQUAD75 and the best fit chemical model is based on the statistical parameters. The effect of solvent on protonation constants is discussed based on electrostatic and non-electrostatic forces operating on the protonation equilibria. Distribution of species, protonation equilibria and effect of influential parameters on the protonation constants are also presented.

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