Cephalothin-induced tachycardia following aortic valve replacement.

Prophylactic antibiotics, though routinely used by most surgeons for patients undergoing open-heart surgery, are of questionable value and may cause serious side effects. Cephalothin-sodium-induced tachycardia accompanied by hemolysis and hyperpyrexia presents problems of diagnosis. The reported patient's survival is attributed to discontinuation of the drug.

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