A Model for Migratory B Cell Oscillations from Receptor Down-Regulation Induced by External Chemokine Fields

[1]  M. Groettrup,et al.  Ubiquitylation of the chemokine receptor CCR7 enables efficient receptor recycling and cell migration , 2012, Journal of Cell Science.

[2]  M. Shlomchik,et al.  Germinal center selection and the development of memory B and plasma cells , 2012, Immunological reviews.

[3]  R. Brink,et al.  EBI2 Operates Independently of but in Cooperation with CXCR5 and CCR7 To Direct B Cell Migration and Organization in Follicles and the Germinal Center , 2011, The Journal of Immunology.

[4]  J. Fox,et al.  Mechanisms regulating chemokine receptor activity , 2011, Immunology.

[5]  Laura M Lechuga,et al.  Technical Advance: Surface plasmon resonance‐based analysis of CXCL12 binding using immobilized lentiviral particles , 2011, Journal of leukocyte biology.

[6]  Joost B. Beltman,et al.  B cells within germinal centers migrate preferentially from dark to light zone , 2011, Proceedings of the National Academy of Sciences.

[7]  Martin Meier-Schellersheim,et al.  Systems biology in immunology: a computational modeling perspective. , 2011, Annual review of immunology.

[8]  Christopher A Hunter,et al.  Dendritic Cells Distinguish Individual Chemokine Signals through CCR7 and CXCR4 , 2011, The Journal of Immunology.

[9]  Michael Meyer-Hermann,et al.  Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter , 2010, Cell.

[10]  Gib Bogle,et al.  Agent‐based simulation of T‐cell activation and proliferation within a lymph node , 2010, Immunology and cell biology.

[11]  Michael Meyer-Hermann,et al.  Germinal centres seen through the mathematical eye: B-cell models on the catwalk. , 2009, Trends in immunology.

[12]  E. Butcher,et al.  Modeling the Role of Homologous Receptor Desensitization in Cell Gradient Sensing1 , 2008, The Journal of Immunology.

[13]  Michael Meyer-Hermann,et al.  University of Birmingham Deriving a germinal center lymphocyte migration model from two-photon data , 2008 .

[14]  Tilo Beyer,et al.  Cell transmembrane receptors determine tissue pattern stability. , 2008, Physical review letters.

[15]  Cliburn Chan,et al.  The Multiscale Systems Immunology project: software for cell-based immunological simulation , 2008, Source Code for Biology and Medicine.

[16]  J. Cyster,et al.  Germinal-center organization and cellular dynamics. , 2007, Immunity.

[17]  M. Shlomchik,et al.  In vivo imaging studies shed light on germinal-centre development , 2007, Nature Reviews Immunology.

[18]  Anja E Hauser,et al.  Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns. , 2007, Immunity.

[19]  T. Kepler,et al.  Spatiotemporal programming of a simple inflammatory process , 2007, Immunological reviews.

[20]  Michael L. Dustin,et al.  In vivo imaging of germinal centres reveals a dynamic open structure , 2007, Nature.

[21]  Jason G. Cyster,et al.  Imaging of Germinal Center Selection Events During Affinity Maturation , 2007, Science.

[22]  R. Förster,et al.  Balanced expression of CXCR5 and CCR7 on follicular T helper cells determines their transient positioning to lymph node follicles and is essential for efficient B-cell help. , 2005, Blood.

[23]  Marc Thilo Figge,et al.  Stochastic discrete event simulation of germinal center reactions. , 2005, Physical review. E, Statistical, nonlinear, and soft matter physics.

[24]  J. Cyster,et al.  Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5 , 2004, Nature Immunology.

[25]  Willy Govaerts,et al.  MATCONT: A MATLAB package for numerical bifurcation analysis of ODEs , 2003, TOMS.

[26]  O. Weiner,et al.  Regulation of cell polarity during eukaryotic chemotaxis: the chemotactic compass. , 2002, Current opinion in cell biology.

[27]  J. Cyster,et al.  Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position , 2002, Nature.

[28]  A. Deutsch,et al.  Recycling probability and dynamical properties of germinal center reactions. , 2001, Journal of theoretical biology.

[29]  H. Othmer,et al.  A model for individual and collective cell movement in Dictyostelium discoideum. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[30]  J. Hoxie,et al.  Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4 , 1997, The Journal of cell biology.

[31]  Jennifer J. Linderman,et al.  Receptor Up-regulation, Internalization, and Interconverting Receptor States , 1996, The Journal of Biological Chemistry.

[32]  T. Kepler,et al.  Somatic hypermutation in B cells: an optimal control treatment. , 1993, Journal of theoretical biology.

[33]  D. Lauffenburger,et al.  Receptors: Models for Binding, Trafficking, and Signaling , 1993 .

[34]  A S Perelson,et al.  Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation. , 1993, Immunology today.

[35]  D. Lauffenburger,et al.  Kinetic analysis of chemotactic peptide receptor modulation , 1982, The Journal of cell biology.

[36]  S. Zigmond Consequences of chemotactic peptide receptor modulation for leukocyte orientation , 1981, The Journal of cell biology.

[37]  M. Meyer-Hermann,et al.  Modelling Intravital Two-Photon Data of Lymphocyte Migration and Interaction , 2011 .

[38]  J. Singh,et al.  Toward quantitative models of germinal center dynamics , 2002 .

[39]  Christopher Jones,et al.  Geometric singular perturbation theory , 1995 .