Characterization and visualization of the liposecretion process taking place during ceiling culture of human mature adipocytes

To investigate and further characterize the process of mature adipocyte dedifferentiation. Our hypothesis was that dedifferentiation does not involve mitosis but rather a phenomenon of liposecretion.

[1]  Lucio Della Guardia,et al.  Key‐genes regulating the liposecretion process of mature adipocytes , 2018, Journal of cellular physiology.

[2]  M. Vivarelli,et al.  Human White Adipocytes Convert Into “Rainbow” Adipocytes In Vitro , 2017, Journal of cellular physiology.

[3]  J. Fradette,et al.  Role of the TGF‐β pathway in dedifferentiation of human mature adipocytes , 2017, FEBS open bio.

[4]  M. Vohl,et al.  Temporal Changes in Gene Expression Profile during Mature Adipocyte Dedifferentiation , 2017, International journal of genomics.

[5]  S. Cinti,et al.  Adipocytes WNT5a mediated dedifferentiation: a possible target in pancreatic cancer microenvironment , 2016, Oncotarget.

[6]  A. Tchernof,et al.  Characterization of Dedifferentiating Human Mature Adipocytes from the Visceral and Subcutaneous Fat Compartments: Fibroblast-Activation Protein Alpha and Dipeptidyl Peptidase 4 as Major Components of Matrix Remodeling , 2015, PloS one.

[7]  N. Itoh,et al.  The Fibroblast Growth Factor signaling pathway , 2015, Wiley interdisciplinary reviews. Developmental biology.

[8]  M. Du,et al.  Bovine dedifferentiated adipose tissue (DFAT) cells , 2013, Adipocyte.

[9]  N. Rhind,et al.  Signaling pathways that regulate cell division. , 2012, Cold Spring Harbor perspectives in biology.

[10]  S. Cinti,et al.  Human Dedifferentiated Adipocytes Show Similar Properties to Bone Marrow‐Derived Mesenchymal Stem Cells , 2012, Stem cells.

[11]  Y. Okazaki,et al.  A novel preadipocyte cell line established from mouse adult mature adipocytes. , 2004, Biochemical and biophysical research communications.

[12]  A. Matsuda,et al.  2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine: a novel anticancer nucleoside analog that causes both DNA strand breaks and G(2) arrest. , 2001, Molecular pharmacology.

[13]  A. Barnett,et al.  Ceiling culture of mature human adipocytes: use in studies of adipocyte functions. , 2000, The Journal of endocrinology.

[14]  M. Inagaki,et al.  Identification of a Novel Phosphorylation Site on Histone H3 Coupled with Mitotic Chromosome Condensation* , 1999, The Journal of Biological Chemistry.

[15]  T. Hunter,et al.  Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport , 1991, The Journal of cell biology.

[16]  S. N. Timasheff,et al.  Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline. , 1991, Biochemistry.

[17]  H. Sugihara,et al.  Primary cultures of unilocular fat cells: characteristics of growth in vitro and changes in differentiation properties. , 1986, Differentiation; research in biological diversity.

[18]  M. Rodbell The metabolism of isolated fat cells , 1965 .

[19]  Mitosis: Methods and Protocols , 2022, Methods in Molecular Biology.

[20]  Daniel,et al.  Tissue-Specific Progenitor and Stem Cells Pluripotent Stem Cells Derived From Mouse and Human White Mature Adipocytes , 2014 .