PS9, Derived from an Aquatic Fungus Virulent Protein, Glycosyl Hydrolase, Arrests MCF-7 Proliferation by Regulating Intracellular Reactive Oxygen Species and Apoptotic Pathways
暂无分享,去创建一个
M. Arasu | N. Al-Dhabi | T. Ahamad | J. Arockiaraj | M. Abu Haija | P. Sarkar | Ajay Guru | Manikandan Velayutham | P. Arumugam | Shanavas Shajahan | Kanchana Karuppiah | K. Choi
[1] M. Arasu,et al. Nimbin analogs N5 and N7 regulate the expression of lipid metabolic genes and inhibit lipid accumulation in high-fat diet-induced zebrafish larvae: An antihyperlipidemic study. , 2022, Tissue & cell.
[2] J. Arockiaraj,et al. β-cells regeneration by WL15 of cysteine and glycine-rich protein 2 which reduces alloxan induced β-cell dysfunction and oxidative stress through phosphoenolpyruvate carboxykinase and insulin pathway in zebrafish in-vivo larval model , 2022, Molecular Biology Reports.
[3] Palaniselvam Kuppusamy,et al. Withaferin A targets the membrane of Pseudomonas aeruginosa and mitigates the inflammation in zebrafish larvae; an in vitro and in vivo approach. , 2022, Microbial pathogenesis.
[4] F. Al-Misned,et al. Copper sulfate induced toxicological impact on in-vivo zebrafish larval model protected due to acacetin via anti-inflammatory and glutathione redox mechanism. , 2022, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
[5] J. Arockiaraj,et al. Neuroprotective effect of Biochanin a against Bisphenol A-induced prenatal neurotoxicity in zebrafish by modulating oxidative stress and locomotory defects , 2022, Neuroscience Letters.
[6] J. Arockiaraj,et al. Pro-inflammatory cytokine molecules from Boswellia serrate suppresses lipopolysaccharides induced inflammation demonstrated in an in-vivo zebrafish larval model , 2022, Molecular Biology Reports.
[7] J. Arockiaraj,et al. Reverse pharmacology of Nimbin-N2 attenuates alcoholic liver injury and promotes the hepatoprotective dual role of improving lipid metabolism and downregulating the levels of inflammatory cytokines in zebrafish larval model , 2022, Molecular and Cellular Biochemistry.
[8] J. Arockiaraj,et al. Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection. , 2022, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
[9] J. Arockiaraj,et al. Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety‐like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae , 2022, Environmental toxicology.
[10] J. Arockiaraj,et al. Molecular Docking of SA11, RF13 and DI14 Peptides from Vacuolar Protein Sorting Associated Protein 26B Against Cancer Proteins and In vitro Investigation of its Anticancer Potency in Hep-2 Cells , 2022, International Journal of Peptide Research and Therapeutics.
[11] J. Arockiaraj,et al. Lipid-Lowering and Antioxidant Activity of RF13 Peptide From Vacuolar Protein Sorting-Associated Protein 26B (VPS26B) by Modulating Lipid Metabolism and Oxidative Stress in HFD Induced Obesity in Zebrafish Larvae , 2022, International Journal of Peptide Research and Therapeutics.
[12] Palaniselvam Kuppusamy,et al. Hydroxyl containing benzo[b]thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle. , 2022, Life sciences.
[13] J. Arockiaraj,et al. Protective effect of morin by targeting mitochondrial reactive oxygen species induced by hydrogen peroxide demonstrated at a molecular level in MDCK epithelial cells , 2022, Molecular Biology Reports.
[14] Palaniselvam Kuppusamy,et al. Antiproliferation of MP12 derived from a fungus, Aphanomyces invadans virulence factor, cysteine-rich trypsin inhibitor on human laryngeal epithelial cells, and in vivo zebrafish embryo model. , 2022, Toxicon : official journal of the International Society on Toxinology.
[15] M. Arasu,et al. Anti‐inflammatory role demonstrated both in vitro and in vivo models using nonsteroidal tetranortriterpenoid, Nimbin (N1) and its analogs (N2 and N3) that alleviate the domestication of alternative medicine , 2022, Cell biology international.
[16] Zhou Chen,et al. Brevilaterin B from Brevibacillus laterosporus has selective antitumor activity and induces apoptosis in epidermal cancer , 2021, World Journal of Microbiology and Biotechnology.
[17] P. Gopinath,et al. 6‐Gingerol and Semisynthetic 6‐Gingerdione Counteract Oxidative Stress Induced by ROS in Zebrafish , 2021, Chemistry & biodiversity.
[18] Muhammad Dain Yazid,et al. Zebrafish as a Model System to Study the Mechanism of Cutaneous Wound Healing and Drug Discovery: Advantages and Challenges , 2021, Pharmaceuticals.
[19] J. Arockiaraj,et al. GP13, an Arthrospira platensis cysteine desulfurase-derived peptide, suppresses oxidative stress and reduces apoptosis in human leucocytes and zebrafish (Danio rerio) embryo via attenuated caspase-3 expression , 2021, Journal of King Saud University - Science.
[20] M. Arasu,et al. NV14 from serine O‐acetyltransferase of cyanobacteria influences the antioxidant enzymes in vitro cells, gene expression against H2O2 and other responses in vivo zebrafish larval model , 2021, Cell biology international.
[21] Mina Emadi Shaibani,et al. Production and Fractionation of Rocky Shore Crab (Grapsus albacarinous) Protein Hydrolysate by Ultrafiltration Membrane: Assessment of Antioxidant and Cytotoxic Activities , 2021 .
[22] C. Nantasenamat,et al. A novel peptide isolated from garlic shows anticancer effect against leukemic cell lines via interaction with Bcl‐2 family proteins , 2021, Chemical biology & drug design.
[23] A. Jemal,et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries , 2021, CA: a cancer journal for clinicians.
[24] C. de la Fuente-Nunez,et al. Net charge tuning modulates the antiplasmodial and anticancer properties of peptides derived from scorpion venom , 2021, Journal of peptide science : an official publication of the European Peptide Society.
[25] S. Chutipongtanate,et al. Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application (Review) , 2020, International journal of oncology.
[26] A. Alshatwi,et al. Potential Metabolite Nymphayol Isolated from Water Lily (Nymphaea stellata) Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions , 2020, Metabolites.
[27] J. Arockiaraj,et al. Pathogenicity and Pathobiology of Epizootic Ulcerative Syndrome (EUS) Causing Fungus Aphanomyces invadans and Its Immunological Response in Fish , 2020 .
[28] W. Yap,et al. Anticancer Mechanisms of Bioactive Peptides. , 2020, Protein and peptide letters.
[29] M. Arumugam,et al. Reactive oxygen species generation and mitochondrial dysfunction for the initiation of apoptotic cell death in human hepatocellular carcinoma HepG2 cells by a cyclic dipeptide Cyclo(-Pro-Tyr) , 2020, Molecular Biology Reports.
[30] M. Xie,et al. Anti-cancer peptides: classification, mechanism of action, reconstruction and modification , 2020, Open Biology.
[31] D. Stojanovski,et al. Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks , 2019, Open Biology.
[32] Andy Chi-Lung Lee,et al. A Comprehensive Review on Current Advances in Peptide Drug Development and Design , 2019, International journal of molecular sciences.
[33] J. Arockiaraj,et al. Design and characterization of a novel Arthrospira platensis glutathione oxido‐reductase‐derived antioxidant peptide GM15 and its potent anti‐cancer activity via caspase‐9 mediated apoptosis in oral cancer cells , 2019, Free radical biology & medicine.
[34] J. Arockiaraj,et al. Intensifying the Anticancer Potential of Cationic Peptide Derived from Serine Threonine Protein Kinase of Teleost by Tagging with Oligo Tryptophan , 2019, International Journal of Peptide Research and Therapeutics.
[35] Zongyun Chen,et al. Bldesin, the first functionally characterized pathogenic fungus defensin with Kv1.3 channel and chymotrypsin inhibitory activities , 2018, Journal of biochemical and molecular toxicology.
[36] M. Arasu,et al. A comparative transcriptome approach for identification of molecular changes in Aphanomyces invadans infected Channa striatus , 2018, Molecular Biology Reports.
[37] Jae Young Ko,et al. Protective effect of polysaccharides from Celluclast-assisted extract of Hizikia fusiforme against hydrogen peroxide-induced oxidative stress in vitro in Vero cells and in vivo in zebrafish. , 2018, International journal of biological macromolecules.
[38] J. Pouysségur,et al. The Central Role of Amino Acids in Cancer Redox Homeostasis: Vulnerability Points of the Cancer Redox Code , 2017, Front. Oncol..
[39] X. Su,et al. Anticancer potential of bioactive peptides from animal sources (Review). , 2017, Oncology reports.
[40] M. Arasu,et al. A Cumulative Strategy to Predict and Characterize Antimicrobial Peptides (AMPs) from Protein Database , 2017, International Journal of Peptide Research and Therapeutics.
[41] Mário R. Felício,et al. Peptides with Dual Antimicrobial and Anticancer Activities , 2017, Front. Chem..
[42] R. Ahmad,et al. Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration , 2017, BMC Cancer.
[43] C. Bai,et al. Anti-tumoral effects of a trypsin inhibitor derived from buckwheat in vitro and in vivo , 2015, Molecular medicine reports.
[44] M. Mirghani,et al. Cytotoxic effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract , 2014, BMC Complementary and Alternative Medicine.
[45] J. Musarrat,et al. Copper Oxide Nanoparticles Induced Mitochondria Mediated Apoptosis in Human Hepatocarcinoma Cells , 2013, PloS one.
[46] Y. Jeon,et al. Protective effect of marine algae phlorotannins against AAPH-induced oxidative stress in zebrafish embryo. , 2013, Food chemistry.
[47] F. Schroeder,et al. A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatus. , 2013, Journal of the American Chemical Society.
[48] Ashok Sharma,et al. Structure prediction and functional characterization of secondary metabolite proteins of Ocimum , 2011, Bioinformation.
[49] A. Omar,et al. Selective Cytotoxicity of Goniothalamin against Hepatoblastoma HepG2 Cells , 2011, Molecules.
[50] G. Padmaja,et al. Inhibitory effect of an extract of Curcuma zedoariae on human cervical carcinoma cells , 2008, Medicinal Chemistry Research.
[51] B. Henrissat,et al. Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[52] OUP accepted manuscript , 2022, Bioinformatics.