A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

Claude Bouchard | Beverley Balkau | Bengt Sennblad | Philippe Froguel | Luigi Ferrucci | Meena Kumari | Perttu Salo | Markus Perola | Eric Boerwinkle | Richa Saxena | Vilmundur Gudnason | Vincent Mooser | Igor Rudan | Lars Lind | Marie-France Hivert | Josée Dupuis | Tamara B Harris | Min A Jhun | Lawrence F Bielak | Patricia A Peyser | Sharon L R Kardia | Simon Heath | Mark I McCarthy | Leena Peltonen | Johanna Kuusisto | John Blangero | Harry Campbell | Reedik Mägi | Nicholas J Wareham | Michael Stumvoll | David Couper | Lars Lannfelt | Karin Leander | Bruna Gigante | Jaana Lindstrom | Caroline Hayward | Michael Boehnke | Hanieh Yaghootkar | Peter Kovacs | Alena Stančáková | Panos Deloukas | Claudia Langenberg | Erik Ingelsson | Rainer Rauramaa | Anuj Goel | Leif Groop | Pierre Meneton | Inga Prokopenko | Göran Hallmans | Ulf de Faire | Maria Dimitriou | Kathleen Stirrups | Emil Rehnberg | Aroon Hingorani | Albert Hofman | Anke Tönjes | Jose C Florez | Paul W Franks | Veikko Salomaa | Aarno Palotie | Lina Zgaga | Han Chen | May E. Montasser | Yurii Aulchenko | James S Pankow | Mariza de Andrade | Dorret I Boomsma | Gonneke Willemsen | Lenore J Launer | Stella Trompet | J Wouter Jukema | Nancy L Pedersen | Jaakko Kaprio | Yan V Sun | Yan V. Sun | Jouke-Jan Hottenga | Stavroula Kanoni | Jari Lahti | Sara M. Willems | Michael Marmot | Francis S Collins | Denis Rybin | Ola Hansson | Mika Kivimaki | Lyle J Palmer | Jaakko Tuomilehto | Maria Sabater-Lleal | Stefania Bandinelli | Ozren Polasek | Paul C D Johnson | Eric Brunner | Nicholas L Smith | Ingrid B Borecki | Claes Ladenvall | Louis Perusse | Michael A Province | Joseph Hung | Anders Hamsten | Elisabeth Widen | Nita G Forouhi | Gudny Eiriksdottir | Thor Aspelund | Yvonne Böttcher | Veronique Vitart | Ivana Kolcic | Paul C. D. Johnson | Mustafa Atalay | Eleanor Wheeler | Karen L Mohlke | Robert A Scott | Jennie Hui | Pau Navarro | Peter P Pramstaller | Najaf Amin | Peter Vollenweider | Jian'an Luan | Min A. Jhun | Naveed Sattar | Richard M Watanabe | Richard N Bergman | Jeanette S. Andrews | Kirsten Ohm Kyvik | Alan F Wright | Jacques S Beckmann | Laura J Rasmussen-Torvik | Robert Clarke | Marjo-Riitta Jarvelin | M. Jarvelin | J. Grimsby | Toshiko Tanaka | S. Bandinelli | A. Hofman | A. Uitterlinden | J. Pankow | L. Ferrucci | R. Mägi | M. McCarthy | P. Deloukas | R. Saxena | K. Stirrups | L. Peltonen | J. Beckmann | E. Boerwinkle | V. Salomaa | M. Perola | L. Groop | M. Laakso | J. O’Connell | F. Collins | M. Boehnke | S. Heath | G. Lathrop | T. Frayling | J. Perry | V. Gudnason | C. Bouchard | R. Bergman | I. Borecki | Albert Vernon Smith | J. Blangero | A. Hingorani | D. Couper | C. Duijn | J. Witteman | C. Fox | J. Hui | J. Beilby | L. Palmer | S. Kardia | K. Small | J. Kaprio | Yongmei Liu | D. Siscovick | S. Wild | B. Penninx | G. Willemsen | M. Province | J. Peden | N. Sattar | A. Palotie | E. Ingelsson | M. Marmot | K. Mohlke | L. Bonnycastle | M. Erdos | P. Chines | A. Jackson | A. Swift | N. Narisu | R. Watanabe | J. Tuomilehto | B. Voight | V. Lyssenko | J. Florez | J. Rotter | B. Balkau | P. Froguel | L. Lind | D. Zélénika | T. Harris | T. Lakka | R. Rauramaa | I. Rudan | D. Boomsma | M. Stumvoll | J. Meigs | L. Bielak | P. Peyser | N. Wareham | Han Chen | J. Dupuis | K. Rice | V. Lagou | J. Hottenga | C. Ladenvall | A. Hamsten | P. Magnusson | N. Pedersen | J. Smit | J. Eriksson | A. Jula | I. Prokopenko | P. Franks | V. Mooser | J. Lindström | M. Uusitupa | J. Blangero | J. Jukema | Y. Böttcher | A. Wright | H. Watkins | B. Oostra | K. Ong | I. Barroso | T. Johnson | N. Amin | C. Hayward | S. Kanoni | I. Kolčić | J. Lahti | O. Polašek | V. Vitart | H. Campbell | G. Dedoussis | M. Dimitriou | G. Eiriksdottir | L. Launer | K. Räikkönen | P. Vollenweider | G. Waeber | E. Widén | James F. Wilson | T. Aspelund | L. Lannfelt | L. Pérusse | P. Galan | S. Hercberg | R. Clarke | A. Manning | A. Goel | J. Luan | R. Scott | A. Stančáková | N. Forouhi | B. Gigante | G. Hallmans | J. Kuusisto | C. Langenberg | J. O'connell | K. Leander | N. Bouatia-Naji | Mario A. Morken | P. Meneton | A. Shuldiner | N. Glazer | Y. Aulchenko | E. Sijbrands | R. Loos | R. Strawbridge | Ching‐Ti Liu | D. Rybin | W. Kao | E. Rehnberg | M. Atalay | E. Eury | S. Lobbens | B. Sennblad | S. Keinanen-Kiukaanniemi | T. Saaristo | M. Montasser | D. Shungin | A. Hicks | M. Kumari | A. Ruokonen | M. Kivimaki | K. Kyvik | P. Pramstaller | P. Schwarz | Guo Li | E. Brunner | P. Navarro | E. Wheeler | P. Kovacs | L. Zgaga | A. Tönjes | D. Waterworth | S. Trompet | C. Bellis | I. Ford | M. Vohl | H. Yaghootkar | E. D. Geus | C. Lecoeur | U. Faire | M. Andrade | O. Hansson | U. Seedorf | J. Hung | J. Egan | O. Carlson | D. Savage | M. Franzosi | L. Rasmussen-Torvik | T. Zemunik | M. Peričić | M. Järvelin | M. Hivert | D. Barnes | G. Cadby | M. Martínez-Larrad | P. Salo | P. An | J. Andrews | M. Boban | D. Budimir | A. Corbatón-Anchuelo | E. D. Geus | Paul C D Johnson | J. Lindstrom | I. Miljkovic | M. Pehlić | M. Sabater-Lleal | M. Serrano-Ríos | N. Smith | M. Vikström | Andrew A. Hicks | G. Dedoussis | G. Lathrop | G Mark Lathrop | Benjamin F Voight | Yongmei Liu | David S Siscovick | Gerard Waeber | Eric J G Sijbrands | Caroline S Fox | Narisu Narisu | Ian Ford | Aimo Ruokonen | Alan R Shuldiner | Serge Hercberg | Nabila Bouatia-Naji | Markku Laakso | Ben A Oostra | James F Wilson | Andrew A Hicks | Matti Uusitupa | Nicole L Glazer | Jerome I Rotter | Andre G Uitterlinden | Jacqueline C M Witteman | Diana Zelenika | Valeriya Lyssenko | Antti Jula | Ines Barroso | Patrik K E Magnusson | Toby Johnson | Hugh Watkins | Marie-Claude Vohl | Toshiko Tanaka | Ching-Ti Liu | Alisa K Manning | James B Meigs | Dawn M Waterworth | Cecile Lecoeur | Anne U Jackson | Ken K Ong | John R B Perry | Peter S Chines | Lori L Bonnycastle | Michael R Erdos | Johan G Eriksson | Mario A Morken | John F Peden | Rona J Strawbridge | Amy J Swift | Sarah H Wild | John P Beilby | Timothy M Frayling | Cornelia M van Duijn | Ruth J F Loos | Katri Räikkönen | Pilar Galan | Daniel Barnes | J. Eriksson | David B Savage | Brenda Penninx | George V Dedoussis | Iva Miljkovic | Gemma Cadby | Johannes H Smit | Guo Li | Tatijana Zemunik | Mladen Boban | Maria Grazia Franzosi | Udo Seedorf | Vasiliki Lagou | Sara M Willems | Ping An | Ken Rice | Kerrin S Small | Dmitry Shungin | Marina Pehlic | Timo Lakka | Peter Schwarz | Marijana Pericic | Claire Bellis | Stéphane Lobbens | Elodie Eury | Jonna L Grimsby | Timo Saaristo | Josephine M Egan | Jeanette S Andrews | Olga Carlson | Max Vikström | Maria Teresa Martinez-Larrad | May E Montasser | Danijela Budimir | Arturo Corbatón-Anchuelo | Eco de Geus | W H Kao | Sirkka Keinanen-Kiukaanniemi | Jeff O'Connell | Manuel Serrano-Rios | A. Smith | R. Saxena | Harry Campbell | Joseph Hung | Danijela Budimir | L. Lind | James F. Wilson | I. Ford | A. Tönjes | Peter Kovacs | A. Smith | E. Geus | Daniel R. Barnes | Yan V. Sun | A. Wright | R. Watanabe | J. Eriksson | A. Uitterlinden | R. Scott | Narisu Narisu | T. Harris | Reedik Mägi | A. Goel | Toshiko Tanaka | J. Eriksson | A. Hofman | B. Oostra | J. Perry | D. Boomsma | R. Loos | M. Morken | R. Scott | Marina Pehlić | M. McCarthy | A. Wright | F. Collins | A. Wright | M. Kivimäki | Jerome I. Rotter | Markku Laakso | Peter E. H. Schwarz | Alisa K Manning | Denis Rybin | Josephine M. Egan | Paul W. Franks | A. Hofman | R. Scott | Ruth J. F. Loos | Alan F. Wright | Iva Miljkovic | Johannes H. Smit | B.W.J.H. Penninx | A. Palotie | Jennie Hui | N. Smith | Robert A. Scott | Jacques S. Beckmann | Hugh Watkins | Eric J. Brunner | A. Jackson | J. Jukema | Sarah H. Wild | Nancy L. Pedersen | Anders Hamsten | Han Chen | Yongmei Liu | Michael Stumvoll | Yan V. Sun | N. Wareham | Ken K. Ong | Matti Uusitupa | Robert Clarke | Lars Lannfelt | Richa Saxena | V. Mooser | Caroline S. Fox | J. Tuomilehto | P. Froguel | M. McCarthy | A. Uitterlinden | Elodie Eury | Eric J. G. Sijbrands | J. Kaprio | Ching-Ti Liu | David J. Couper | Kenneth M. Rice | S. Hercberg | Jonna L. Grimsby | P. Salo | Ping An | Mustafa Atalay | R. Bergman | Claude Bouchard | Arturo Corbató-Anchuelo | Pilar Galan | S. Heath | Paul C. D. Johnson | K. O. Kyvik | M. Marmot | L. Peltonen | Inês Barroso | R. M. Watanabe | L. Groop | C. V. Duijn | Jose C. Florez | David B. Savage | L. Ferrucci | Sirkka M Keinänen-Kiukaanniemi

[1]  E. Oetjen,et al.  Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes , 2011, Diabetes.

[2]  Thomas Lumley,et al.  Behavior of QQ-Plots and Genomic Control in Studies of Gene-Environment Interaction , 2011, PloS one.

[3]  P. Elliott,et al.  Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels , 2011, Circulation.

[4]  W. Rathmann,et al.  Insulin resistance influences the association of adiponectin levels with diabetes incidence in two population-based cohorts: the Cooperative Health Research in the Region of Augsburg (KORA) S4/F4 study and the Framingham Offspring Study , 2011, Diabetologia.

[5]  Simon C. Potter,et al.  The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study , 2011, PLoS genetics.

[6]  Josée Dupuis,et al.  Meta‐analysis of gene‐environment interaction: joint estimation of SNP and SNP × environment regression coefficients , 2011, Genetic epidemiology.

[7]  G. Abecasis,et al.  MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes , 2010, Genetic epidemiology.

[8]  J. Florez,et al.  The genetics of type 2 diabetes: what have we learned from GWAS? , 2010, Annals of the New York Academy of Sciences.

[9]  J. Pankow,et al.  Impact of repeated measures and sample selection on genome‐wide association studies of fasting glucose , 2010, Genetic epidemiology.

[10]  Yusuke Nakamura,et al.  Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population , 2010, Journal of Human Genetics.

[11]  Thomas Meitinger,et al.  Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution , 2010, Nature Genetics.

[12]  Inês Barroso,et al.  Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[13]  D. Altshuler,et al.  A map of human genome variation from population-scale sequencing , 2010, Nature.

[14]  Christian Gieger,et al.  Edinburgh Research Explorer Common variants at 10 genomic loci influence hemoglobin A(C) levels via glycemic and nonglycemic pathways , 2010 .

[15]  U. Ekelund,et al.  Genetic Susceptibility to Obesity and Related Traits in Childhood and Adolescence , 2010, Diabetes.

[16]  Ayellet V. Segrè,et al.  Hundreds of variants clustered in genomic loci and biological pathways affect human height , 2010, Nature.

[17]  Tanya M. Teslovich,et al.  Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids , 2010, Nature.

[18]  Ayellet V. Segrè,et al.  Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis , 2010, Nature Genetics.

[19]  Jake K. Byrnes,et al.  Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls , 2010 .

[20]  Eric Boerwinkle,et al.  A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. , 2010, American journal of human genetics.

[21]  Alex Doney,et al.  Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge , 2010, Nature Genetics.

[22]  Christian Gieger,et al.  New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk , 2010, Nature Genetics.

[23]  Jake K. Byrnes,et al.  Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls , 2010, Nature.

[24]  Tanya M. Teslovich,et al.  Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index , 2010 .

[25]  Yurii S. Aulchenko,et al.  ProbABEL package for genome-wide association analysis of imputed data , 2010, BMC Bioinformatics.

[26]  Ferdinand von Meyenn,et al.  Regulation of adaptive behaviour during fasting by hypothalamic Foxa2 , 2009, Nature.

[27]  Hilary F Ryder,et al.  Decision Analysis and Cost-effectiveness Analysis. , 2009, Seminars in spine surgery.

[28]  V. Trischitta,et al.  Insulin signaling regulating genes: effect on T2DM and cardiovascular risk , 2009, Nature Reviews Endocrinology.

[29]  M. Mangino,et al.  Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene–obesity interaction , 2009, Diabetologia.

[30]  Marc W. Kirschner,et al.  Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling , 2009, Nature.

[31]  Jean Tichet,et al.  Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia , 2009, Nature Genetics.

[32]  Laura J. Scott,et al.  Edinburgh Research Explorer Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution , 2022 .

[33]  P. Donnelly,et al.  A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.

[34]  P. Ridker,et al.  Polymorphism in the CETP Gene Region, HDL Cholesterol, and Risk of Future Myocardial Infarction: Genomewide Analysis Among 18 245 Initially Healthy Women From the Women’s Genome Health Study , 2009, Circulation. Cardiovascular genetics.

[35]  M. McCarthy,et al.  Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data , 2009, Diabetes.

[36]  G. Abecasis,et al.  Genotype imputation. , 2009, Annual review of genomics and human genetics.

[37]  T. Hansen,et al.  Common nonsynonymous variants in PCSK1 confer risk of obesity , 2008, Nature Genetics.

[38]  C. Fox,et al.  Haplotype Structure of the ENPP1 Gene and Nominal Association of the K121Q Missense Single Nucleotide Polymorphism With Glycemic Traits in the Framingham Heart Study , 2008, Diabetes.

[39]  Xiao-Hua Zhou,et al.  Statistical Methods for Meta‐Analysis , 2008 .

[40]  J. Florez.  Newly identified loci highlight beta cell dysfunction as a key cause of type 2 diabetes: Where are the insulin resistance genes? , 2008, Diabetologia.

[41]  F. Horber,et al.  The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies , 2008, BMC Medical Genetics.

[42]  John D. Storey,et al.  Mapping the Genetic Architecture of Gene Expression in Human Liver , 2008, PLoS biology.

[43]  E. Rampersaud,et al.  Identification of Novel Candidate Genes for Type 2 Diabetes From a Genome-Wide Association Scan in the Old Order Amish , 2007, Diabetes.

[44]  G. Abecasis,et al.  Optimal designs for two‐stage genome‐wide association studies , 2007, Genetic epidemiology.

[45]  S. Jacobsen,et al.  UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells , 2007, Science.

[46]  C. Gieger,et al.  Genomewide association analysis of coronary artery disease. , 2007, The New England journal of medicine.

[47]  P. Donnelly,et al.  A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.

[48]  A. Minenna,et al.  Heterogeneous Effect of Peroxisome Proliferator‐activated Receptor γ2 Ala12 Variant on Type 2 Diabetes Risk , 2007, Obesity.

[49]  David M Nathan,et al.  Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. , 2007, The Journal of clinical endocrinology and metabolism.

[50]  T. Hudson,et al.  A genome-wide association study identifies novel risk loci for type 2 diabetes , 2007, Nature.

[51]  Peter Kraft,et al.  Exploiting Gene-Environment Interaction to Detect Genetic Associations , 2007, Human Heredity.

[52]  These authors contributed equally to this work. , 2007 .

[53]  S. Kahn,et al.  Mechanisms linking obesity to insulin resistance and type 2 diabetes , 2006, Nature.

[54]  P. Scherer,et al.  Adipose tissue-derived factors: impact on health and disease. , 2006, Endocrine reviews.

[55]  G. Abecasis,et al.  Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies , 2006, Nature Genetics.

[56]  Pardis C Sabeti,et al.  Common deletion polymorphisms in the human genome , 2006, Nature Genetics.

[57]  S. Hubbard,et al.  Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. , 2005, Molecular cell.

[58]  A. Favier,et al.  In silico identification and expression of SLC30 family genes: An expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression , 2004, BMC Genomics.

[59]  G. Barish,et al.  PPARs and the complex journey to obesity , 2004, Nature Medicine.

[60]  R. Stein,et al.  Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family. , 2004, The Journal of clinical endocrinology and metabolism.

[61]  M. White,et al.  The IRS-signalling system: A network of docking proteins that mediate insulin action , 1998, Molecular and Cellular Biochemistry.

[62]  R. Turner,et al.  Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man , 1985, Diabetologia.

[63]  Alberto Riva,et al.  A SNP-centric database for the investigation of the human genome , 2004, BMC Bioinformatics.

[64]  J. Klingensmith,et al.  Cordon-bleu is a conserved gene involved in neural tube formation. , 2003, Developmental biology.

[65]  O. Michielin,et al.  Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1. , 2003, The Journal of clinical endocrinology and metabolism.

[66]  F. Giorgino,et al.  Two Novel Proteins That Are Linked to Insulin-like Growth Factor (IGF-I) Receptors by the Grb10 Adapter and Modulate IGF-I Signaling* , 2003, Journal of Biological Chemistry.

[67]  J. Lillehaug,et al.  Platelet-derived Growth Factor (PDGF)-C, a PDGF Family Member with a Vascular Endothelial Growth Factor-like Structure* , 2003, The Journal of Biological Chemistry.

[68]  Z. Bloomgarden,et al.  Inflammation and insulin resistance. , 2003, Diabetes care.

[69]  S. Thompson,et al.  Quantifying heterogeneity in a meta‐analysis , 2002, Statistics in medicine.

[70]  Tom H. Pringle,et al.  The human genome browser at UCSC. , 2002, Genome research.

[71]  J. Resau,et al.  ARAP1: a point of convergence for Arf and Rho signaling. , 2002, Molecular cell.

[72]  H. Brunner.  Annual Review of Genomics and Human Genetics , 2001, European Journal of Human Genetics.

[73]  S. Henikoff,et al.  Predicting deleterious amino acid substitutions. , 2001, Genome research.

[74]  S. Schurmans,et al.  The lipid phosphatase SHIP2 controls insulin sensitivity , 2001, Nature.

[75]  H. Lodish,et al.  Tankyrase Is a Golgi-associated Mitogen-activated Protein Kinase Substrate That Interacts with IRAP in GLUT4 Vesicles* , 2000, The Journal of Biological Chemistry.

[76]  E S Lander,et al.  The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. , 2000, Nature genetics.

[77]  A. Krainer,et al.  The type 2C Ser/Thr phosphatase PP2Cgamma is a pre-mRNA splicing factor. , 1999, Genes & development.

[78]  T. Lange,et al.  Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. , 1998, Science.

[79]  F. Endo,et al.  Prolidase Deficiency , 1985, Ryoikibetsu shokogun shirizu.

[80]  W. Clarke,et al.  Early-onset type-ll diabetes mellitus (MODY4) linked to IPF1 , 1997, Nature Genetics.

[81]  T. Sanke,et al.  Human Prohormone Convertase 3 Gene: Exon-Intron Organization and Molecular Scanning for Mutations in Japanese Subjects With NIDDM , 1996, Diabetes.

[82]  P. Schofield,et al.  The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes. , 1996, Brain research. Molecular brain research.

[83]  R. Roth,et al.  Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[84]  Diana B. Petitti,et al.  Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis: Methods for Quantitative Synthesis in Medicine , 1994 .

[85]  Nature Genetics , 1991, Nature.

[86]  A. Folsom,et al.  The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. , 1989, American journal of epidemiology.