Retinal vasculature of the fovea of the squirrel monkey, Saimiri sciureus: Three‐dimensional architecture, visual screening, and relationships to the neuronal layers

The retinal vasculature of the fovea of squirrel monkeys was studied in retinal whole mounts and in sections of the same retinas. At the center of the fovea there is an approximately circular avascular zone surrounded by a set of terminal capillaries in the inner nuclear layer. Within the foveal depression, four capillary planes that bear a precise relationship to the neuronal organization appear in a specific sequence with increasing eccentricity. The first plane to be established is the dominant, most voluminous one, located closest to the photoreceptors at the deep (sclerad) border of the inner nuclear layer. A second major plane appears next at the sclerad border of the ganglion cell layer.

[1]  J. Gilchrist,et al.  PSYCHOPHYSICAL MEASUREMENT OF THE FOVEAL AVASCULAR ZONE * , 1987, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[2]  C. Sharpe,et al.  The visibility and fading of thin lines visualized by their controlled movement across the retina , 1972, The Journal of physiology.

[3]  J. Chase,et al.  The evolution of retinal vascularization in mammals. A comparison of vascular and avascular retinae. , 1982, Ophthalmology.

[4]  L. Feeney-Burns,et al.  Aging human RPE: morphometric analysis of macular, equatorial, and peripheral cells. , 1984, Investigative ophthalmology & visual science.

[5]  D P CUTHBERTSON,et al.  Passage of plasma albumin into the intestine of the sheep , 1961, The Journal of physiology.

[6]  Colin T. Dollery,et al.  The Retinal Circulation , 1972 .

[7]  M. Iwasaki,et al.  Relation between superficial capillaries and foveal structures in the human retina. , 1986, Investigative ophthalmology & visual science.

[8]  J. Horton,et al.  Mapping of cytochrome oxidase patches and ocular dominance columns in human visual cortex. , 1984, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[9]  L Z Wu,et al.  Characteristics of the capillary-free zone in the normal human macula. , 1985, Japanese journal of ophthalmology.

[10]  D. Bok,et al.  Blood vascular abnormalities in the degenerative mouse retina (C57BL/6J-rd le). , 1984, Investigative ophthalmology & visual science.

[11]  M. Goldberg,et al.  Sickling hemoglobinopathies; macular and perimacular vascular abnormalities. , 1974, Archives of ophthalmology.

[12]  L. Laatikainen,et al.  Capillary-free area of the fovea with advancing age. , 1977, Investigative ophthalmology & visual science.

[13]  P. Henkind,et al.  Aging and degeneration of the human macula. 1. Outer nuclear layer and photoreceptors. , 1981, The British journal of ophthalmology.

[14]  M. Wong-Riley,et al.  The histochemical localization of cytochrome oxidase in the retina and lateral geniculate nucleus of the ferret, cat, and monkey, with particular reference to retinal mosaics and ON/OFF-center visual channels , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[15]  J. Weiter,et al.  Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration. , 1989, Investigative ophthalmology & visual science.

[16]  R. Penner Fluorescein Angiography of the Retina. , 1970 .

[17]  J Yeung,et al.  Macular-foveal capillaries in human retina. , 1973, Australian journal of ophthalmology.

[18]  M Palta,et al.  Abnormalities of the foveal avascular zone in diabetic retinopathy. , 1984, Archives of ophthalmology.

[19]  W. Heriot,et al.  Chapter 10 Plasticity of the retinal vasculature , 1986 .

[20]  D. Worthen,et al.  Histology of the Human Eye. , 1972 .

[21]  清水 弘一,et al.  Structure of ocular vessels , 1978 .

[22]  J. Blanks,et al.  Vascular atrophy in the retinal degenerative rd mouse , 1986, The Journal of comparative neurology.

[23]  D. Snodderly,et al.  Mapping Retinal Features in a Freely Moving Eye with Precise Control of Retinal Stimulus Position , 1978 .

[24]  D. R. Anderson The retinal capillary bed at the posterior pole of primate eyes. , 1971, American journal of ophthalmology.

[25]  R A Weale,et al.  On the retinal vasculature of the human fovea. , 1974, Experimental eye research.

[26]  P. Henkind,et al.  Radial peripapillary capillaries of the retina. I. Anatomy: human and comparative. , 1967, The British journal of ophthalmology.

[27]  D. Simons,et al.  Cytochrome oxidase staining in the rat smI barrel cortex , 1985, The Journal of comparative neurology.

[28]  David G. Cogan,et al.  Retinal Vascular Patterns: Part II. Human Retinal Vessels Studied in Three Dimensions , 1961 .

[29]  M. A. Bell,et al.  Laminar variation in the microvascular architecture of normal human visual cortex (area 17) , 1985, Brain Research.

[30]  Urmi Patel,et al.  Non-random distribution of blood vessels in the posterior region of the rat somatosensory cortex , 1983, Brain Research.