Bacterial ghosts as adjuvants: mechanisms and potential

[1]  John-hwa Lee,et al.  Characterization and Evaluation of a Salmonella enterica Serotype Senftenberg Mutant Created by Deletion of Virulence-Related Genes for Use as a Live Attenuated Vaccine , 2016, Clinical and Vaccine Immunology.

[2]  John-hwa Lee,et al.  Protective efficacy and immune responses by homologous prime-booster immunizations of a novel inactivated Salmonella Gallinarum vaccine candidate , 2016, Clinical and experimental vaccine research.

[3]  I. A. Hajam,et al.  Bacterial Ghosts of Escherichia coli Drive Efficient Maturation of Bovine Monocyte-Derived Dendritic Cells , 2015, PloS one.

[4]  Kun Cai,et al.  Novel fusion antigen displayed-bacterial ghosts vaccine candidate against infection of Escherichia coli O157:H7 , 2015, Scientific Reports.

[5]  S. Eo,et al.  Evaluation of Salmonella Gallinarum ghost formulated with Montanide™ ISA 70 VG adjuvant as a vaccine against fowl typhoid. , 2015, Acta veterinaria Hungarica.

[6]  W. Zhou,et al.  Immune responses and protection induced by Brucella suis S2 bacterial ghosts in mice. , 2015, Veterinary immunology and immunopathology.

[7]  W. Lubitz,et al.  Escherichia coli Nissle 1917 bacterial ghosts retain crucial surface properties and express chlamydial antigen: an imaging study of a delivery system for the ocular surface , 2015, Drug design, development and therapy.

[8]  C. L. Ventola.  The antibiotic resistance crisis: part 1: causes and threats. , 2015, P & T : a peer-reviewed journal for formulary management.

[9]  John-hwa Lee,et al.  Comparative evaluation of Salmonella Enteritidis ghost vaccines with a commercial vaccine for protection against internal egg contamination with Salmonella. , 2014, Vaccine.

[10]  John-hwa Lee,et al.  Characterization of a Salmonella Typhimurium ghost carrying an adjuvant protein as a vaccine candidate for the protection of chickens against virulent challenge , 2014, Avian pathology : journal of the W.V.P.A.

[11]  I. A. Hajam,et al.  Immunological evaluation of mannosylated chitosan nanoparticles based foot and mouth disease virus DNA vaccine, pVAC FMDV VP1-OmpA in guinea pigs. , 2014, Biologicals : journal of the International Association of Biological Standardization.

[12]  E. Bergmann-Leitner,et al.  Adjuvants in the Driver’s Seat: How Magnitude, Type, Fine Specificity and Longevity of Immune Responses Are Driven by Distinct Classes of Immune Potentiators , 2014, Vaccines.

[13]  John-hwa Lee,et al.  Salmonella enterica Serovar Enteritidis Ghosts Carrying the Escherichia coli Heat-Labile Enterotoxin B Subunit Are Capable of Inducing Enhanced Protective Immune Responses , 2014, Clinical and Vaccine Immunology.

[14]  I. A. Hajam,et al.  Co-administration of flagellin augments immune responses to inactivated foot-and-mouth disease virus (FMDV) antigen. , 2013, Research in veterinary science.

[15]  L. Barrio,et al.  TLR4 Signaling Shapes B Cell Dynamics via MyD88-Dependent Pathways and Rac GTPases , 2013, The Journal of Immunology.

[16]  W. Lubitz,et al.  In vitro and in vivo uptake study of Escherichia coli Nissle 1917 bacterial ghosts: cell-based delivery system to target ocular surface diseases. , 2013, Investigative ophthalmology & visual science.

[17]  F. Alanazi,et al.  Sponge-Like: A New Protocol for Preparing Bacterial Ghosts , 2013, TheScientificWorldJournal.

[18]  V. Dirsch,et al.  Modulation of bacterial ghosts – induced nitric oxide production in macrophages by bacterial ghost‐delivered resveratrol , 2013, The FEBS journal.

[19]  M. Loessner,et al.  Bacteriophage endolysins as novel antimicrobials. , 2012, Future microbiology.

[20]  Shibo Jiang,et al.  Salmonella typhi Ty21a bacterial ghost vector augments HIV-1 gp140 DNA vaccine-induced peripheral and mucosal antibody responses via TLR4 pathway. , 2012, Vaccine.

[21]  E. Browne.  Regulation of B‐cell responses by Toll‐like receptors , 2012, Immunology.

[22]  Chang-Seon Song,et al.  A review of vaccine development and research for industry animals in Korea , 2012, Clinical and experimental vaccine research.

[23]  John-hwa Lee,et al.  Construction of a Salmonella Gallinarum ghost as a novel inactivated vaccine candidate and its protective efficacy against fowl typhoid in chickens , 2012, Veterinary Research.

[24]  Jonathan G. Rud,et al.  Essential role of IL-6 in protection against H1N1 influenza virus by promoting neutrophil survival in the lung , 2012, Mucosal Immunology.

[25]  P. Dormitzer,et al.  New technologies for influenza vaccines , 2012, Human vaccines & immunotherapeutics.

[26]  N. Hynes.  Bacterial flagellin- a novel adjuvant for vaccine strategies , 2011 .

[27]  S. Akira,et al.  Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. , 2011, Immunity.

[28]  Siguo Liu,et al.  Salmonella enteritidis ghost vaccine induces effective protection against lethal challenge in specific-pathogen-free chicks. , 2011, Immunobiology.

[29]  C. Bode,et al.  TLR-based immune adjuvants. , 2011, Vaccine.

[30]  L. Dixon,et al.  Current strategies for subunit and genetic viral veterinary vaccine development. , 2011, Virus research.

[31]  Y. Kawaoka,et al.  Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses , 2011, Virology Journal.

[32]  L. Wahl,et al.  Involvement of TLR2 and TLR4 in cell responses to Rickettsia akari , 2010, Journal of leukocyte biology.

[33]  M. Mildner,et al.  Escherichia coli ghosts promote innate immune responses in human keratinocytes. , 2010, Biochemical and biophysical research communications.

[34]  M. Esmaeili,et al.  Helicobacter pylori bacterial ghost containing recombinant Omp18 as a putative vaccine. , 2010, Journal of microbiological methods.

[35]  W. Lubitz,et al.  The bacterial ghost platform system , 2010, Bioengineered bugs.

[36]  A. Mailleux,et al.  Probiotic Escherichia coli Nissle 1917 activates DC and prevents house dust mite allergy through a TLR4‐dependent pathway , 2010, European journal of immunology.

[37]  J. Barnett,et al.  Interleukin 12 a Key Immunoregulatory Cytokine in Infection Applications , 2010, International journal of molecular sciences.

[38]  M. Grubman,et al.  Foot and mouth disease virus vaccines. , 2009, Vaccine.

[39]  W. Lubitz,et al.  Bacterial ghosts as a delivery system for zona pellucida-2 fertility control vaccines for brushtail possums (Trichosurus vulpecula). , 2008, Vaccine.

[40]  M. Rojas,et al.  Flagellin Treatment Protects against Chemicals, Bacteria, Viruses, and Radiation1 , 2008, The Journal of Immunology.

[41]  A. Aertsen,et al.  Using Mild High-pressure Shock to Generate Bacterial Ghosts of Escherichia coli , 2008 .

[42]  E. Rajnavölgyi,et al.  Dendritic cell subtypes as primary targets of vaccines: the emerging role and cross-talk of pattern recognition receptors , 2008, Biological chemistry.

[43]  D. Cholujová,et al.  Effective gene transfer to melanoma cells using bacterial ghosts. , 2008, Cancer letters.

[44]  J. Xiang,et al.  CD4+ Th1 cells promote CD8+ Tc1 cell survival, memory response, tumor localization and therapy by targeted delivery of interleukin 2 via acquired pMHC I complexes , 2007, Immunology.

[45]  G. B. Karlsson Hedestam,et al.  DNA vaccines: recent developments and future possibilities. , 2006, Human gene therapy.

[46]  S. K. Kim,et al.  Protection of tilapia (Oreochromis mosambicus) from edwardsiellosis by vaccination with Edwardsiella tarda ghosts. , 2006, Fish & shellfish immunology.

[47]  R. Förster,et al.  Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells , 2006, The Journal of experimental medicine.

[48]  S. Akira,et al.  Pathogen Recognition and Innate Immunity , 2006, Cell.

[49]  S. Mizel,et al.  Flagellin Is an Effective Adjuvant for Immunization against Lethal Respiratory Challenge with Yersinia pestis , 2006, Infection and Immunity.

[50]  Ruslan Medzhitov,et al.  Control of B-cell responses by Toll-like receptors , 2005, Nature.

[51]  A. Atrasheuskaya,et al.  Bacterial Ghosts as an Oral Vaccine: a Single Dose of Escherichia coli O157:H7 Bacterial Ghosts Protects Mice against Lethal Challenge , 2005, Infection and Immunity.

[52]  Reinhard Hohlfeld,et al.  Immunobiology of muscle: advances in understanding an immunological microenvironment. , 2005, Trends in immunology.

[53]  W. Lubitz,et al.  Bacterial ghosts as antigen delivery vehicles. , 2005, Advanced drug delivery reviews.

[54]  A. Hofmann,et al.  Comparative immunogenicity of the hepatitis B virus core 149 antigen displayed on the inner and outer membrane of bacterial ghosts. , 2005, Vaccine.

[55]  W. Lubitz,et al.  Bacterial ghosts--biological particles as delivery systems for antigens, nucleic acids and drugs. , 2004, Current opinion in biotechnology.

[56]  A. Hensel,et al.  T cell-specific immune response induced by bacterial ghosts. , 2004, Medical science monitor : international medical journal of experimental and clinical research.

[57]  Á. Ambrus,et al.  Bacterial ghost technology for pesticide delivery. , 2004, Journal of agricultural and food chemistry.

[58]  W. Lubitz,et al.  Bacterial Ghosts Are an Efficient Delivery System for DNA Vaccines1 , 2004, The Journal of Immunology.

[59]  W. Lubitz,et al.  Bacterial ghosts as novel advanced drug delivery systems: antiproliferative activity of loaded doxorubicin in human Caco-2 cells. , 2004, Journal of controlled release : official journal of the Controlled Release Society.

[60]  W. Lubitz,et al.  Escherichia coli Ghost Production by Expression of Lysis Gene E and Staphylococcal Nuclease , 2003, Applied and Environmental Microbiology.

[61]  W. Lubitz,et al.  Pasteurella multocida- and Pasteurella haemolytica-ghosts: new vaccine candidates. , 2003, Vaccine.

[62]  W. Lubitz,et al.  Construction of recombinant S-layer proteins (rSbsA) and their expression in bacterial ghosts--a delivery system for the nontypeable Haemophilus influenzae antigen Omp26. , 2003, FEMS immunology and medical microbiology.

[63]  N. Pavelka,et al.  The immune response is initiated by dendritic cells via interaction with microorganisms and interleukin-2 production. , 2003, The Journal of infectious diseases.

[64]  A. Aderem,et al.  The Toll-Like Receptor 5 Stimulus Bacterial Flagellin Induces Maturation and Chemokine Production in Human Dendritic Cells1 , 2003, The Journal of Immunology.

[65]  F. Eko,et al.  Recombinant Vibrio cholerae ghosts as a delivery vehicle for vaccinating against Chlamydia trachomatis. , 2003, Vaccine.

[66]  I. Mellman,et al.  Activation of Lysosomal Function During Dendritic Cell Maturation , 2003, Science.

[67]  F. Eko,et al.  Bacterial ghosts as carrier and targeting systems for mucosal antigen delivery , 2003, Expert review of vaccines.

[68]  S. Akira,et al.  Recognition of pathogen-associated molecular patterns by TLR family. , 2003, Immunology letters.

[69]  W. Lubitz,et al.  Online Monitoring of Escherichia coli Ghost Production , 2003, Applied and Environmental Microbiology.

[70]  S. Akira,et al.  Toll-like receptors control activation of adaptive immune responses , 2001, Nature Immunology.

[71]  S. Fürst-Ladani,et al.  Activation, stimulation and uptake of bacterial ghosts in antigen presenting cells. , 2000, Journal of biotechnology.

[72]  A. Hensel,et al.  Intramuscular immunization with genetically inactivated (ghosts) Actinobacillus pleuropneumoniae serotype 9 protects pigs against homologous aerosol challenge and prevents carrier state. , 2000, Vaccine.

[73]  M. Hilleman.  Vaccines in historic evolution and perspective: a narrative of vaccine discoveries. , 2000, Vaccine.

[74]  R. Medzhitov,et al.  Innate immune recognition: mechanisms and pathways , 2000, Immunological reviews.

[75]  W. Lubitz,et al.  Bacterial ghosts as drug carrier and targeting vehicles. , 1999, Journal of controlled release : official journal of the Controlled Release Society.

[76]  J. Ramos,et al.  Characterization of Cell Lysis in Pseudomonas putida Induced upon Expression of Heterologous Killing Genes , 1998, Applied and Environmental Microbiology.

[77]  A. Lefor,et al.  Enhanced cytolytic activity of tumor infiltrating lymphocytes (TILs) derived from an ICAM-1 transfected tumor in a murine model. , 1998, The Journal of surgical research.

[78]  C. Olsen,et al.  Coadministration of DNA Encoding Interleukin-6 and Hemagglutinin Confers Protection from Influenza Virus Challenge in Mice , 1998, Journal of Virology.

[79]  A. Hensel,et al.  Endotoxicity does not limit the use of bacterial ghosts as candidate vaccines. , 1997, Vaccine.

[80]  A. Mccarthy.  Development , 1996, Current Opinion in Neurobiology.

[81]  A. Hensel,et al.  Bacterial ghosts: non-living candidate vaccines. , 1996, Journal of biotechnology.

[82]  A. Hensel,et al.  Induction of protective immunity by aerosol or oral application of candidate vaccines in a dose-controlled pig aerosol infection model. , 1996, Journal of biotechnology.

[83]  P. Perrin,et al.  Inactivation of DNA by β-propiolactone , 1995 .

[84]  K. Timmis,et al.  Inducible cell lysis system for the study of natural transformation and environmental fate of DNA released by cell death , 1994, Journal of bacteriology.

[85]  A. Husband,et al.  The role of interleukin-6 in mucosal IgA antibody responses in vivo. , 1994, Science.

[86]  T. Meyer,et al.  Transformation-mediated exchange of virulence determinants by co-cultivation of pathogenic Neisseriae. , 1992, FEMS microbiology letters.

[87]  M. Szostak,et al.  Endogenous transmembrane tunnel formation mediated by phi X174 lysis protein E , 1990, Journal of bacteriology.

[88]  G. Air,et al.  Epitopes on protein antigens: Misconceptions and realities , 1990, Cell.

[89]  U. Bläsi,et al.  Evidence for membrane-bound oligomerization of bacteriophage phi X174 lysis protein-E. , 1989, The Journal of biological chemistry.

[90]  W. Lubitz,et al.  Biochemical characterization of phi X174-protein-E-mediated lysis of Escherichia coli. , 1989, European journal of biochemistry.

[91]  K. Buckley,et al.  Lytic activity localized to membrane-spanning region of ϕX174 E protein , 1986, Molecular and General Genetics MGG.

[92]  W. Lubitz,et al.  Different sensitivity of autolytic deficient Escherichia coli mutants to the mode of induction , 1984 .

[93]  K. Young,et al.  Lytic action of cloned phi X174 gene E , 1982, Journal of virology.

[94]  I. Tessman,et al.  Identification of lysis protein E of bacteriophage phiX174 , 1978, Journal of virology.

[95]  C. Hutchison,et al.  The process of infection with bacteriophage ΦX174: X. Mutations in a ΦX lysis gene† , 1966 .

[96]  R. Sinsheimer,et al.  The process of infection with bacteriophage φX174: III. Phage maturation and lysis after synchronized infection† , 1965 .

[97]  J. Hurwitz,et al.  The purification and properties of micrococcal nuclease. , 1961, The Journal of biological chemistry.

[98]  M. Strioga,et al.  Bacterial ghosts as adjuvants in syngeneic tumour cell lysate-based anticancer vaccination in a murine lung carcinoma model. , 2017, Oncology reports.

[99]  Zhengxing Chen,et al.  Production of Bacterial Ghosts from Gram-Positive Pathogen Listeria monocytogenes. , 2017, Foodborne pathogens and disease.

[100]  S. Eo,et al.  Generation of Salmonella ghost cells expressing fimbrial antigens of enterotoxigenic Escherichia coli and evaluation of their antigenicity in a murine model. , 2016, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

[101]  Ira Mellman,et al.  Cell biology of antigen processing in vitro and in vivo. , 2005, Annual review of immunology.

[102]  W. Lubitz,et al.  Dynamics of PhiX174 protein E-mediated lysis of Escherichia coli , 2004, Archives of Microbiology.

[103]  W. Lubitz,et al.  Lysis of Escherichia coli by induction of cloned ϕX174 genes , 2004, Molecular and General Genetics MGG.

[104]  T. Doel,et al.  FMD vaccines. , 2003, Virus research.

[105]  M. Hilleman.  Vaccines in historic evolution and perspective: a narrative of vaccine discoveries. , 2000, Journal of human virology.

[106]  A. Hensel,et al.  New strategies for combination vaccines based on the extended recombinant bacterial ghost system. , 1999, Vaccine.

[107]  Dendritic Cells: Unique Leukocyte Populations Which Control the Primary , 1997 .

[108]  P. Perrin,et al.  Inactivation of DNA by beta-propiolactone. , 1995, Biologicals : journal of the International Association of Biological Standardization.

[109]  F. Eko,et al.  Production of Vibrio cholerae ghosts (VCG) by expression of a cloned phage lysis gene: potential for vaccine development. , 1994, Vaccine.

[110]  K. Young,et al.  Deletion and fusion analysis of the phage phi X174 lysis gene E. , 1985, Gene.

[111]  K. Young,et al.  Deletion and fusion analysis of the phage φX174 lysis gene E , 1985 .

[112]  W. Lubitz,et al.  Lysis of Escherichia coli by induction of cloned phi X174 genes. , 1982, Molecular & general genetics : MGG.

[113]  C. Anfinsen,et al.  8 Staphylococcal Nuclease, Chemical Properties and Catalysis , 1971 .

[114]  C. Hutchison,et al.  The process of infection with bacteriophage phi-X174. X. Mutations in a phi-X Lysis gene. , 1966, Journal of molecular biology.

[115]  W. Zillig,et al.  STUDIES ON THE LYSIS OF ESCHERICHIA COLI C BY BACTERIOPHAGE PHI-X174. , 1965, Virology.

[116]  D. Denhardt,et al.  The process of infection with bacteriophage phi-X174. 3. Phage maturation and lysis after synchronized infection. , 1965, Journal of molecular biology.