Mechano-regulation of the beating heart at the cellular level--mechanosensitive channels in normal and diseased heart.

[1]  D N Ghista,et al.  Left ventricular wall stress compendium , 2012, Computer methods in biomechanics and biomedical engineering.

[2]  P. Volders,et al.  Arrhythmogenic mechano-electric heterogeneity in the long-QT syndrome. , 2012, Progress in biophysics and molecular biology.

[3]  J. Karemaker,et al.  Abdominal counter pressure in CPR: what about the lungs? An in silico study. , 2012, Resuscitation.

[4]  J. Kalman,et al.  Atrial remodeling in varying clinical substrates within beating human hearts: relevance to atrial fibrillation. , 2012, Progress in biophysics and molecular biology.

[5]  H. V. Van Spall,et al.  Strain, strain rate, and the force frequency relationship in patients with and without heart failure. , 2012, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[6]  Sung Eun Kim,et al.  Piezos are pore-forming subunits of mechanically activated channels , 2011, Nature.

[7]  A. Patapoutian,et al.  The role of Drosophila Piezo in mechanical nociception , 2011, Nature.

[8]  Boris Martinac,et al.  Bacterial Mechanosensitive Channels as a Paradigm for Mechanosensory Transduction , 2011, Cellular Physiology and Biochemistry.

[9]  J. Sabourin,et al.  A key role of TRPC channels in the regulation of electromechanical activity of the developing heart. , 2011, Cardiovascular research.

[10]  P. Kohl,et al.  Cardiac mechano-electric coupling and arrhythmias , 2011 .

[11]  D. Allen,et al.  Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry. , 2011, Cardiovascular research.

[12]  F. Sachs,et al.  The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4. , 2011, Biochemistry.

[13]  L. Csernoch,et al.  Overexpression of transient receptor potential canonical type 1 (TRPC1) alters both store operated calcium entry and depolarization-evoked calcium signals in C2C12 cells. , 2011, Cell calcium.

[14]  U. Schotten,et al.  Leaky ryanodine receptors in the failing heart: the root of all evil? , 2011, Cardiovascular research.

[15]  G. Booz,et al.  Three 4-letter words of hypertension-related cardiac hypertrophy: TRPC, mTOR, and HDAC. , 2011, Journal of molecular and cellular cardiology.

[16]  M. Nishida,et al.  TRPC3-mediated Ca2+ influx contributes to Rac1-mediated production of reactive oxygen species in MLP-deficient mouse hearts. , 2011, Biochemical and biophysical research communications.

[17]  F. Sachse,et al.  Strain transfer in ventricular cardiomyocytes to their transverse tubular system revealed by scanning confocal microscopy. , 2011, Biophysical journal.

[18]  A. Alonso,et al.  TRPC channels underlie cholinergic plateau potentials and persistent activity in entorhinal cortex , 2011, Hippocampus.

[19]  Catherine E. Morris,et al.  Voltage-Gated Channel Mechanosensitivity: Fact or Friction? , 2011, Front. Physio..

[20]  J. Molkentin,et al.  TRPC Channels As Effectors of Cardiac Hypertrophy , 2011, Circulation research.

[21]  Frederick Sachs,et al.  Mechanosensitivity of Nav1.5, a voltage‐sensitive sodium channel , 2010, The Journal of physiology.

[22]  R. Marthan,et al.  Stretch-activated channels in pulmonary arterial smooth muscle cells from normoxic and chronically hypoxic rats. , 2010, Cell calcium.

[23]  David E. Clapham,et al.  International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family , 2010, Pharmacological Reviews.

[24]  K. Nakao,et al.  Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart , 2010, Circulation research.

[25]  F. Duprat,et al.  Canonical TRP channels and mechanotransduction: from physiology to disease states , 2010, Pflügers Archiv - European Journal of Physiology.

[26]  M. Chalfie,et al.  Eukaryotic mechanosensitive channels. , 2010, Annual review of biophysics.

[27]  E. White,et al.  Mechano-Electric Feedback in the Fish Heart , 2010, PloS one.

[28]  J. Molkentin,et al.  TRPC channels are necessary mediators of pathologic cardiac hypertrophy , 2010, Proceedings of the National Academy of Sciences.

[29]  D. Allen,et al.  Calcium and the damage pathways in muscular dystrophy. , 2010, Canadian journal of physiology and pharmacology.

[30]  Viatcheslav Gurev,et al.  Mechanisms of Mechanically Induced Spontaneous Arrhythmias in Acute Regional Ischemia , 2010, Circulation research.

[31]  Haixia Huang,et al.  TRPC1 expression and distribution in rat hearts , 2009, European journal of histochemistry : EJH.

[32]  B. Aronow,et al.  Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism , 2009, Proceedings of the National Academy of Sciences.

[33]  L. Birnbaumer,et al.  TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart , 2009, Circulation research.

[34]  Zhong Jian,et al.  Mechanosensitive TRP channels in cardiovascular pathophysiology. , 2009, Pharmacology & therapeutics.

[35]  David E. Schmidt,et al.  On the biomechanics of heart valve function. , 2009, Journal of biomechanics.

[36]  P. Rosenberg,et al.  Mechanosensitive Channels in Striated Muscle and the Cardiovascular System: Not Quite a Stretch Anymore , 2009, Journal of cardiovascular pharmacology.

[37]  M. Asakura,et al.  Global gene expression profiling in the failing myocardium. , 2009, Circulation journal : official journal of the Japanese Circulation Society.

[38]  J. Levine,et al.  TRPC1 and TRPC6 Channels Cooperate with TRPV4 to Mediate Mechanical Hyperalgesia and Nociceptor Sensitization , 2009, The Journal of Neuroscience.

[39]  M. Nowycky,et al.  Reciprocal amplification of ROS and Ca2+ signals in stressed mdx dystrophic skeletal muscle fibers , 2009, Pflügers Archiv - European Journal of Physiology.

[40]  P. Camelliti,et al.  Axial Stretch of Rat Single Ventricular Cardiomyocytes Causes an Acute and Transient Increase in Ca2+ Spark Rate , 2009, Circulation research.

[41]  W. Large,et al.  Identification of canonical transient receptor potential (TRPC) channel proteins in native vascular smooth muscle cells. , 2009, Current medicinal chemistry.

[42]  G. Vassort,et al.  Transient receptor potential: a large family of new channels of which several are involved in cardiac arrhythmia. , 2009, Canadian journal of physiology and pharmacology.

[43]  E. Niggli,et al.  Pathways of abnormal stress-induced Ca2+ influx into dystrophic mdx cardiomyocytes. , 2009, Cell calcium.

[44]  Oliver Friedrich,et al.  Inhibitory Control Over Ca2+ Sparks via Mechanosensitive Channels Is Disrupted in Dystrophin Deficient Muscle but Restored by Mini-Dystrophin Expression , 2008, PloS one.

[45]  Yue-Kun Ju,et al.  Stretch-activated channels in the heart: contributions to length-dependence and to cardiomyopathy. , 2008, Progress in Biophysics and Molecular Biology.

[46]  F. Sachs,et al.  The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms. , 2008, Progress in biophysics and molecular biology.

[47]  Misook Kim,et al.  A tarantula spider toxin, GsMTx4, reduces mechanical and neuropathic pain , 2008, PAIN®.

[48]  Hiroyuki Watanabe,et al.  TRP channel and cardiovascular disease. , 2008, Pharmacology & therapeutics.

[49]  B. Nilius,et al.  TRPC1 channels regulate directionality of migrating cells , 2008, Pflügers Archiv - European Journal of Physiology.

[50]  J. Zwanenburg,et al.  Interventricular mechanical asynchrony in pulmonary arterial hypertension: left-to-right delay in peak shortening is related to right ventricular overload and left ventricular underfilling. , 2008, Journal of the American College of Cardiology.

[51]  D. Bers Calcium cycling and signaling in cardiac myocytes. , 2008, Annual review of physiology.

[52]  B. Nilius,et al.  TRP channels and mechanosensory transduction: insights into the arterial myogenic response , 2008, Pflügers Archiv - European Journal of Physiology.

[53]  David John Adams,et al.  Polymodal Regulation of NMDA Receptor-Channels , 2007, Channels.

[54]  T. Gudermann,et al.  Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1 , 2007, Pflügers Archiv - European Journal of Physiology.

[55]  H. Duff,et al.  Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+. , 2007, Biophysical journal.

[56]  G. Rispoli,et al.  Modulation of the reaction cycle of the Na+:Ca2+, K+ exchanger , 2007, European Biophysics Journal.

[57]  F. Sachs,et al.  Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology. , 2007, Toxicon : official journal of the International Society on Toxinology.

[58]  W. Schilling,et al.  TRPC3 channels colocalize with Na+/Ca2+ exchanger and Na+ pump in axial component of transverse-axial tubular system of rat ventricle. , 2007, American journal of physiology. Heart and circulatory physiology.

[59]  D. Allen,et al.  Intracellular calcium handling in ventricular myocytes from mdx mice. , 2007, American journal of physiology. Heart and circulatory physiology.

[60]  Y. Mori,et al.  Upregulation of TRPC1 in the development of cardiac hypertrophy. , 2006, Journal of molecular and cellular cardiology.

[61]  D. Allen,et al.  Streptomycin reduces stretch-induced membrane permeability in muscles from mdx mice , 2006, Neuromuscular Disorders.

[62]  E. Olson,et al.  TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. , 2006, The Journal of clinical investigation.

[63]  M. Nishida,et al.  TRPC3 and TRPC6 are essential for angiotensin II‐induced cardiac hypertrophy , 2006, The EMBO journal.

[64]  J. Soboloff,et al.  A common mechanism underlies stretch activation and receptor activation of TRPC6 channels , 2006, Proceedings of the National Academy of Sciences.

[65]  P. Bois,et al.  Functional Expression of the TRPM4 Cationic Current in Ventricular Cardiomyocytes From Spontaneously Hypertensive Rats , 2006, Hypertension.

[66]  T. Iwasaka,et al.  Role of mechanical stress in the form of cardiomyocyte death during the early phase of reperfusion. , 2006, Circulation journal : official journal of the Japanese Circulation Society.

[67]  Alan Garny,et al.  Effects of mechanosensitive ion channels on ventricular electrophysiology: experimental and theoretical models , 2006, Experimental physiology.

[68]  P. Murdock,et al.  Tissue Distribution Profiles of the Human TRPM Cation Channel Family , 2006, Journal of receptor and signal transduction research.

[69]  J. Putney Physiological mechanisms of TRPC activation , 2005, Pflügers Archiv.

[70]  J. Joseph,et al.  Doxorubicin activates nuclear factor of activated T-lymphocytes and Fas ligand transcription: role of mitochondrial reactive oxygen species and calcium. , 2005, The Biochemical journal.

[71]  M. Freichel,et al.  Specific detection and semi-quantitative analysis of TRPC4 protein expression by antibodies , 2005, Pflügers Archiv.

[72]  Donald M Bers,et al.  Calcium Signaling in Cardiac Ventricular Myocytes , 2005, Annals of the New York Academy of Sciences.

[73]  Peter Kohl,et al.  Species‐ and Preparation‐Dependence of Stretch Effects on Sino‐Atrial Node Pacemaking , 2005, Annals of the New York Academy of Sciences.

[74]  R. Inoue TRP channels as a newly emerging non-voltage-gated CA2+ entry channel superfamily. , 2005, Current pharmaceutical design.

[75]  Craig Montell,et al.  The TRP Superfamily of Cation Channels , 2005, Science's STKE.

[76]  C. Kung,et al.  Heterologously expressed fungal transient receptor potential channels retain mechanosensitivity in vitro and osmotic response in vivo , 2005, European Biophysics Journal.

[77]  A. Kurosky,et al.  TRPC1 forms the stretch-activated cation channel in vertebrate cells , 2005, Nature Cell Biology.

[78]  D. Allen,et al.  Effects of stretch‐activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse , 2005, The Journal of physiology.

[79]  Weihong Liu,et al.  Differential expression of the mechanosensitive potassium channel TREK‐1 in epicardial and endocardial myocytes in rat ventricle , 2004, Experimental physiology.

[80]  R. Kamm,et al.  Mechanotransduction in Cardiac Myocytes , 2004, Annals of the New York Academy of Sciences.

[81]  C. Romanin,et al.  Ca2+ Signaling by TRPC3 Involves Na+ Entry and Local Coupling to the Na+/Ca2+ Exchanger* , 2004, Journal of Biological Chemistry.

[82]  F. Sachs,et al.  cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels. , 2003, Toxicon : official journal of the International Society on Toxinology.

[83]  Antonio Riccio,et al.  mRNA distribution analysis of human TRPC family in CNS and peripheral tissues. , 2002, Brain research. Molecular brain research.

[84]  W. Schilling,et al.  Selective Association of TRPC Channel Subunits in Rat Brain Synaptosomes* 210 , 2002, The Journal of Biological Chemistry.

[85]  H. Debaix,et al.  Involvement of TRPC in the abnormal calcium influx observed in dystrophic (mdx) mouse skeletal muscle fibers , 2002, The Journal of cell biology.

[86]  F. Sachs,et al.  Solution Structure of Peptide Toxins That Block Mechanosensitive Ion Channels* , 2002, The Journal of Biological Chemistry.

[87]  Donald M Bers,et al.  Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond. , 2002, Journal of molecular and cellular cardiology.

[88]  A. Perraud,et al.  TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization , 2002, Cell.

[89]  A. Franco-Obregón,et al.  Changes in mechanosensitive channel gating following mechanical stimulation in skeletal muscle myotubes from the mdx mouse , 2002, The Journal of physiology.

[90]  C. Kung,et al.  A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca2+-permeable channel in the yeast vacuolar membrane , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[91]  M Lei,et al.  Sudden cardiac death by Commotio cordis: role of mechano-electric feedback. , 2001, Cardiovascular research.

[92]  F. Sachs,et al.  Tarantula peptide inhibits atrial fibrillation , 2001, Nature.

[93]  M. James,et al.  Wall Stress and Hypertension , 2000, Journal of cardiovascular risk.

[94]  F. Sachs,et al.  Identification of a Peptide Toxin from Grammostola spatulata Spider Venom That Blocks Cation-Selective Stretch-Activated Channels , 2000, The Journal of general physiology.

[95]  I. Komuro,et al.  Molecular mechanism of mechanical stress-induced cardiac hypertrophy. , 2000, Japanese heart journal.

[96]  G. Bett,et al.  Stretch-activated whole cell currents in adult rat cardiac myocytes. , 2000, American journal of physiology. Heart and circulatory physiology.

[97]  O. Hamill,et al.  Mechanically gated channel activity in cytoskeleton‐deficient plasma membrane blebs and vesicles from Xenopus oocytes , 2000, The Journal of physiology.

[98]  C. Baumgarten,et al.  Using gadolinium to identify stretch-activated channels: technical considerations. , 1998, American journal of physiology. Cell physiology.

[99]  M. Berridge,et al.  Putative capacitative calcium entry channels: expression of Drosophila trp and evidence for the existence of vertebrate homologues. , 1995, The Biochemical journal.

[100]  R. Johnson,et al.  Membrane stress increases cation permeability in red cells. , 1994, Biophysical journal.

[101]  P. Lipp,et al.  Voltage dependence of Na-Ca exchanger conformational currents. , 1994, Biophysical journal.

[102]  J. Le Guennec,et al.  Streptomycin reverses a large stretch induced increases in [Ca2+]i in isolated guinea pig ventricular myocytes. , 1994, Cardiovascular research.

[103]  D. R. Wagoner,et al.  Mechanosensitive gating of atrial ATP-sensitive potassium channels. , 1993 .

[104]  T. Takahashi,et al.  Roles of mechano-sensitive ion channels, cytoskeleton, and contractile activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[105]  Donald M. Bers,et al.  Excitation-Contraction Coupling and Cardiac Contractile Force , 1991, Developments in Cardiovascular Medicine.

[106]  C. Morris,et al.  Failure to elicit neuronal macroscopic mechanosensitive currents anticipated by single-channel studies. , 1991, Science.

[107]  J. Lansman Blockade of current through single calcium channels by trivalent lanthanide cations. Effect of ionic radius on the rates of ion entry and exit , 1990, The Journal of general physiology.

[108]  R. Virmani,et al.  Sudden cardiac death. , 1987, Human pathology.

[109]  Gordon Dg The physics of left ventricular ejection and its implications for muscle mechanics. , 1976 .

[110]  B. R. Jewell,et al.  The contribution of activation processes to the length–tension relation of cardiac muscle , 1974, Nature.

[111]  E. Sonnenblick,et al.  Maximal rate of pressure fall (peak negative dP-dt) during ventricular relaxation. , 1972, Cardiovascular research.

[112]  Ming-hui Li,et al.  Structural biology of TRP channels. , 2014, Handbook of experimental pharmacology.

[113]  I. Ambudkar,et al.  Transient Receptor Potential Channels , 2013 .

[114]  Brij B. Singh,et al.  The TR (i)P to Ca²⁺ signaling just got STIMy: an update on STIM1 activated TRPC channels. , 2012, Frontiers in bioscience.

[115]  G. Isenberg,et al.  Mechanical deformation of ventricular myocytes modulates both TRPC6 and Kir2.3 channels. , 2009, Cell Calcium.

[116]  A. Kurosky,et al.  Revisiting TRPC1 and TRPC6 mechanosensitivity , 2007, Pflügers Archiv - European Journal of Physiology.

[117]  J. Meister,et al.  Stretch-elicited calcium responses in the intact mouse thoracic aorta. , 2007, Cell calcium.

[118]  B. Nilius,et al.  Transient receptor potential channels in mechanosensing and cell volume regulation. , 2007, Methods in enzymology.

[119]  Ares Pasipoularides,et al.  Cardiac mechanics: Basic and clinical contemporary research , 2006, Annals of Biomedical Engineering.

[120]  C. Morris,et al.  Studying the mechanosensitivity of voltage-gated channels using oocyte patches. , 2006, Methods in molecular biology.

[121]  A. Franco-Obregón,et al.  Stretch-inactivated Channels in Skeletal Muscle , 2005 .

[122]  A. Kamkin,et al.  Mechano-Electric Feedback in the Heart: Evidence from Intracellular Microelectrode Recordings on Multicellular Preparations and Single Cells from Healthy and Diseased Tissue , 2005 .

[123]  C. Romanin,et al.  Ca(2+) signaling by TRPC3 involves Na(+) entry and local coupling to the Na(+)/Ca(2+) exchanger. , 2004, The Journal of biological chemistry.

[124]  O. Hamill,et al.  Induced membrane hypo/hyper-mechanosensitivity: a limitation of patch-clamp recording. , 1997, Annual review of physiology.

[125]  E. White,et al.  The effects of increasing cell length on auxotonic contractions; membrane potential and intracellular calcium transients in single guinea‐pig ventricular myocytes , 1993, Experimental physiology.

[126]  D. Gordon The physics of left ventricular ejection and its implications for muscle mechanics. , 1976, European journal of cardiology.