Role of urinary cations in the etiology of interstitial cystitis: A multisite study

To determine whether patients with interstitial cystitis have elevated levels of toxic urinary cations, to identify and quantify these cationic metabolites, and to assess their cytotoxicity.

[1]  D. Wood,et al.  The effects of recreational ketamine cystitis on urinary tract reconstruction – a surgical challenge , 2018, BJU international.

[2]  Zhongjie Lu,et al.  Changes to the bladder epithelial barrier are associated with ketamine-induced cystitis , 2017, Experimental and therapeutic medicine.

[3]  Yongxuan Su,et al.  Increased toxic urinary cations in males with interstitial cystitis: a possible cause of bladder symptoms , 2016, World Journal of Urology.

[4]  Yuan-Hong Jiang,et al.  Revisiting the Role of Potassium Sensitivity Testing and Cystoscopic Hydrodistention for the Diagnosis of Interstitial Cystitis , 2016, PloS one.

[5]  Hsueh-Kung Lin,et al.  Increased bladder permeability in interstitial cystitis/painful bladder syndrome , 2015, Translational andrology and urology.

[6]  Yongxuan Su,et al.  Role of urinary cations in the aetiology of bladder symptoms and interstitial cystitis , 2014, BJU international.

[7]  R. Moldwin,et al.  Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions , 2012, BJU international.

[8]  Natasha Naidu,et al.  A multi-site study confirms abnormal glycosylation in the Tamm-Horsfall protein of patients with interstitial cystitis. , 2011, The Journal of urology.

[9]  C. Parsons.  The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain , 2011, BJU international.

[10]  A. Kunselman,et al.  Urine markers do not predict biopsy findings or presence of bladder ulcers in interstitial cystitis/painful bladder syndrome. , 2008, The Journal of urology.

[11]  A. Datta,et al.  Defective Tamm-Horsfall protein in patients with interstitial cystitis. , 2007, The Journal of urology.

[12]  J. Kusek,et al.  Prospective evaluation of candidate urine and cell markers in patients with interstitial cystitis enrolled in a randomized clinical trial of Bacillus Calmette Guerin (BCG) , 2007, World Journal of Urology.

[13]  A. Arsanjani,et al.  Role of sialic acid in urinary cytoprotective activity of Tamm-Horsfall protein. , 2007, Urology.

[14]  M. Rajasekaran,et al.  Toxic factors in human urine that injure urothelium , 2006, International journal of urology : official journal of the Japanese Urological Association.

[15]  M. Rajasekaran,et al.  Tamm-Horsfall protein protects urothelial permeability barrier. , 2005, Urology.

[16]  James A Koziol,et al.  Increased prevalence of interstitial cystitis: previously unrecognized urologic and gynecologic cases identified using a new symptom questionnaire and intravesical potassium sensitivity. , 2002, Urology.

[17]  R. Moldwin,et al.  Urinary substance P concentration correlates with urinary frequency and urgency in interstitial cystitis patients treated with intravesical dimethyl sulfoxide and not intravesical anesthetic cocktail. , 2001, Urology.

[18]  D. Erickson.  Urine markers of interstitial cystitis. , 2001, Urology.

[19]  C. Parsons,et al.  Cyto-injury factors in urine: a possible mechanism for the development of interstitial cystitis. , 2000, The Journal of urology.

[20]  C. Parsons,et al.  Urothelial cytoprotective activity of Tamm–Horsfall protein isolated from the urine of healthy subjects and patients with interstitial cystitis , 2000, International journal of urology : official journal of the Japanese Urological Association.

[21]  M. Herderich,et al.  Tryptophan glycoconjugates in food and human urine. , 1999, The Biochemical journal.

[22]  C. Parsons,et al.  The role of urinary potassium in the pathogenesis and diagnosis of interstitial cystitis. , 1998, The Journal of urology.

[23]  J W Warren,et al.  Decreased 3H-thymidine incorporation by human bladder epithelial cells following exposure to urine from interstitial cystitis patients. , 1996, The Journal of urology.

[24]  J. D. Lilly,et al.  Epithelial dysfunction in nonbacterial cystitis (interstitial cystitis). , 1991, The Journal of urology.

[25]  J. D. Lilly,et al.  Bladder surface glycosaminoglycans is a human epithelial permeability barrier. , 1990, Surgery, gynecology & obstetrics.

[26]  A. Wein,et al.  Summary of the National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases Workshop on Interstitial Cystitis, National Institutes of Health, Bethesda, Maryland, August 28-29, 1987. , 1988, The Journal of urology.

[27]  C. Parsons,et al.  Abnormal sensitivity to intravesical potassium in interstitial cystitis and radiation cystitis , 1994, Neurourology and urodynamics.

[28]  R. Hurst,et al.  Bladder surface glycosaminoglycans: an epithelial permeability barrier. , 1990, The Journal of urology.