An analysis of sebum excretion rate, bacterial population and the production rate of free fatty acids on human skin

Bacteria were sampled using a ‘scrub’ technique from the skin surface of the faces of forty‐nine female subjects aged 18–21 years. The sebum excretion rate was determined by a gravimetric method and the level of free fatty acids by titration. The production rate of free fatty acids was calculated from the product of the concentration of free fatty acids in the sebum and the sebum excretion rate.

[1]  V. Dole,et al.  Microdetermination of long-chain fatty acids in plasma and tissues. , 1960, The Journal of biological chemistry.

[2]  John S. Strauss,et al.  The Quantitative Gravimetric Determination of Sebum Production , 1961 .

[3]  A. Kligman,et al.  A new method for the quantitative investigation of cutaneous bacteria. , 1965, The Journal of investigative dermatology.

[4]  W. S. Silver.  Microbial ecology. , 1967, Science.

[5]  W. Cunliffe,et al.  THE RATE OF SEBUM EXCRETION IN MAN , 1969, The British journal of dermatology.

[6]  A M Kligman,et al.  The role of the aerobic microflora in the genesis of fatty acids in human surface lipids. , 1970, The Journal of investigative dermatology.

[7]  A M Kligman,et al.  Ecological effects of oral antibiotics on the microflora of human skin. , 1971, Archives of dermatology.

[8]  A M Kligman,et al.  Control of free fatty acids in human surface lipids by Corynebacterium acnes. , 1971, The Journal of investigative dermatology.

[9]  J. Leyden,et al.  Age-related changes in the resident bacterial flora of the human face. , 1975, The Journal of investigative dermatology.

[10]  C. Evans,et al.  Persistent individual differences in the bacterial flora of the skin of the forehead: numbers of propionibacteria. , 1975, The Journal of investigative dermatology.

[11]  J. Fulton,et al.  The inability of a bacterial lipase inhibitor to control acne vulgaris. , 1977, The Journal of investigative dermatology.

[12]  D. A. Ferguson,et al.  Nutritional requirements of anaerobic coryneforms , 1978, Journal of bacteriology.

[13]  J. Leyden,et al.  Regional variations of cutaneous propionibacteria , 1978, Applied and environmental microbiology.

[14]  Acne vulgaris: is the bacterial population size significant? , 1980, The British journal of dermatology.