Association of maternal and fetal LEPR common variants with maternal glycemic traits during pregnancy

[1]  Lihua Zhang,et al.  Relationship between polymorphisms of the lipid metabolism-related gene PLA2G16 and risk of colorectal cancer in the Chinese population , 2018, Functional & Integrative Genomics.

[2]  Wei Li,et al.  Relationships between plasma leptin levels, leptin G2548A, leptin receptor Gln223Arg polymorphisms and gestational diabetes mellitus in Chinese population , 2016, Scientific Reports.

[3]  Y. Liu,et al.  Association of LEPR Gln223Arg polymorphism with T2DM: A meta-analysis. , 2015, Diabetes research and clinical practice.

[4]  S. Bonassi,et al.  Genetic determinants of quantitative traits associated with cardiovascular disease risk. , 2015, Mutation research.

[5]  A. Cândido,et al.  IGF2, LEPR, POMC, PPARG, and PPARGC1 gene variants are associated with obesity-related risk phenotypes in Brazilian children and adolescents , 2015, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[6]  R. Tungtrongchitr,et al.  Measurement of the levels of leptin, BDNF associated with polymorphisms LEP G2548A, LEPR Gln223Arg and BDNF Val66Met in Thai with metabolic syndrome , 2014, Diabetology & Metabolic Syndrome.

[7]  Ya Liu,et al.  Association of four insulin resistance genes with type 2 diabetes mellitus and hypertension in the Chinese Han population , 2014, Molecular Biology Reports.

[8]  Timothy E. Reddy,et al.  Identification of HKDC1 and BACE2 as Genes Influencing Glycemic Traits During Pregnancy Through Genome-Wide Association Studies , 2013, Diabetes.

[9]  J. Maymó,et al.  Activated Translation Signaling in Placenta from Pregnant Women with Gestational Diabetes Mellitus: Possible Role of Leptin , 2013, Hormone and Metabolic Research.

[10]  L. Jin,et al.  Genome‐wide association study validation identifies novel loci for atherosclerotic cardiovascular disease , 2012, Journal of thrombosis and haemostasis : JTH.

[11]  蔡輔仁,et al.  Gene polymorphisms of adiponectin and leptin receptor are associated with early onset of type 2 diabetes mellitus in the Taiwanese population , 2012 .

[12]  D. Dunger,et al.  The Role of Inflammatory Pathway Genetic Variation on Maternal Metabolic Phenotypes during Pregnancy , 2012, PloS one.

[13]  P. Gu,et al.  Association of leptin receptor gene polymorphisms and essential hypertension in a Chinese population , 2012, Journal of Endocrinological Investigation.

[14]  Sung Hee Choi,et al.  A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women , 2012, Diabetes.

[15]  G. Ferns,et al.  Selection of the appropriate method for the assessment of insulin resistance , 2011, BMC medical research methodology.

[16]  M. K. Garg,et al.  Study of beta-cell function (by HOMA model) in metabolic syndrome , 2011, Indian journal of endocrinology and metabolism.

[17]  N. Stefan,et al.  Evaluation of Fasting State-/Oral Glucose Tolerance Test-Derived Measures of Insulin Release for the Detection of Genetically Impaired β-Cell Function , 2010, PloS one.

[18]  Y. Kesäniemi,et al.  Leptin receptor Lys109Arg and Gln223Arg polymorphisms are associated with early atherosclerosis. , 2010, Metabolic syndrome and related disorders.

[19]  S. Subramanian,et al.  Association of polymorphisms in leptin receptor gene with obesity and type 2 diabetes in the local population of Coimbatore , 2010, Indian journal of human genetics.

[20]  O. Franco,et al.  Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in U.S. Women , 2009, Diabetes.

[21]  Qi Sun Leptin and Soluble Leptin Receptor Levels in Plasma and Risk of Type 2 Diabetes in US Women: A Prospective Study , 2009 .

[22]  J. Dungan,et al.  Hyperglycemia and Adverse Pregnancy Outcomes , 2009 .

[23]  B. Oh,et al.  Genetic variations in the leptin and leptin receptor genes are associated with type 2 diabetes mellitus and metabolic traits in the Korean female population , 2008, Clinical genetics.

[24]  S. Haffner,et al.  Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test. , 2008, Diabetes.

[25]  F. Schmidt Meta-Analysis , 2008 .

[26]  L. Groop,et al.  Genetics of gestational diabetes mellitus. , 2007, Current medicinal chemistry.

[27]  J. Guízar-Mendoza,et al.  Association analysis of the Gln223Arg polymorphism in the human leptin receptor gene, and traits related to obesity in Mexican adolescents , 2005, Journal of Human Hypertension.

[28]  T. Saruta,et al.  Relationships between serum soluble leptin receptor level and serum leptin and adiponectin levels, insulin resistance index, lipid profile, and leptin receptor gene polymorphisms in the Japanese population. , 2004, Metabolism: clinical and experimental.

[29]  J. Levy,et al.  Use and abuse of HOMA modeling. , 2004, Diabetes care.

[30]  M. Saad,et al.  Association of leptin receptor polymorphism with insulin resistance. , 2004, European journal of endocrinology.

[31]  M. Wagner,et al.  Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24. , 2003, Diabetes.

[32]  M. Bidlingmaier,et al.  Generation of human soluble leptin receptor by proteolytic cleavage of membrane-anchored receptors. , 2001, Endocrinology.

[33]  M. Tadayyon,et al.  Leptin receptor long-form signalling in a human liver cell line. , 2001, Cytokine.

[34]  R. Eastell,et al.  A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women , 2001, Human Genetics.

[35]  D. Schuster,et al.  Cardiovascular risk factors in African-Americans with varying degrees of glucose intolerance. , 1999, Diabetes care.

[36]  J. Friedman,et al.  Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice. , 1999, Diabetes.

[37]  D. Kielar,et al.  Leptin receptor isoforms expressed in human adipose tissue. , 1998, Metabolism: clinical and experimental.

[38]  J. Habener,et al.  Leptin receptors expressed on pancreatic beta-cells. , 1996, Biochemical and biophysical research communications.

[39]  C. Bogardus,et al.  Evidence for Linkage Between a Region on Chromosome 1p and the Acute Insulin Response in Pima Indians , 1995, Diabetes.

[40]  R. Bergman,et al.  Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. , 1981, The Journal of clinical investigation.

[41]  D. Fabian Clinical and experimental , 1981 .

[42]  R. DeFronzo,et al.  Glucose clamp technique: a method for quantifying insulin secretion and resistance. , 1979, The American journal of physiology.

[43]  Yangang Wang,et al.  Gln 223 Arg polymorphism with T 2 DM : A meta-analysis , 2015 .

[44]  A. Sima,et al.  Leptin G-2548A and leptin receptor Q223R gene polymorphisms are not associated with obesity in Romanian subjects. , 2010, Biochemical and biophysical research communications.

[45]  R. Muniyappa,et al.  Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. , 2008, American journal of physiology. Endocrinology and metabolism.

[46]  J. Manson,et al.  Prospective Study of , 2007 .

[47]  G. Frühbeck,et al.  Intracellular signalling pathways activated by leptin. , 2006, The Biochemical journal.

[48]  S. Hauguel-de Mouzon Polar expression and phosphorylation of human leptin receptor isoforms in paired, syncytial, microvillous and basal membranes from human term placenta. , 2003, Placenta.

[49]  G. Medley,et al.  Free leptin, bound leptin, and soluble leptin receptor in normal and diabetic pregnancies. , 1999, The Journal of clinical endocrinology and metabolism.

[50]  K. Johnson An Update. , 1984, Journal of food protection.

[51]  F. Hu,et al.  Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels , 2022 .