Lysosomal metabolism of lipids.
暂无分享,去创建一个
W. J. Johnson | P. Yancey | W J Johnson | G H Rothblat | G. Rothblat | G. J. Warner | G J Warner | P G Yancey | Gregory J. Warner | William J. Johnson | Patricia G. Yancey
[1] H. Shio,et al. Lipoprotein-heparin-fibronectin-denatured collagen complexes enhance cholesteryl ester accumulation in macrophages , 1984, The Journal of cell biology.
[2] D A Agard,et al. Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E. , 1991, Science.
[3] H. Moser,et al. Ceramidase Deficiency in Farber's Disease (Lipogranulomatosis) , 1972, Science.
[4] D. Goodman,et al. The hydrolysis of long-chain fatty acid esters of cholesterol with rat liver enzymes. , 1962, The Journal of biological chemistry.
[5] W. Stoffel,et al. Molecular cloning of the acid sphingomyelinase of the mouse and the organization and complete nucleotide sequence of the gene. , 1992, Biological chemistry Hoppe-Seyler.
[6] A. Poulos,et al. Studies on the activation of the enzymatic hydrolysis of sphingomyelin liposomes. , 1984, Biochimica et biophysica acta.
[7] D. Wenger,et al. Diagnosis of metachromatic leukodystrophy, Krabbe disease, and Farber disease after uptake of fatty acid-labeled cerebroside sulfate into cultured skin fibroblasts. , 1982, The Journal of clinical investigation.
[8] M. Heller,et al. Enzymic hydrolysis of sphingomyelin by rat liver. , 1966, Biochemical Journal.
[9] K. Sandhoff,et al. Soluble sphingomyelinase from human urine as antigen for obtaining anti-sphingomyelinase antibodies. , 1985, Biochimica et biophysica acta.
[10] J. Cortner,et al. Genetic variation of human mononuclear leukocyte lysosomal acid lipase activity. Relationship to atherosclerosis. , 1986, Atherosclerosis.
[11] J. Callahan,et al. Purification of sphingomyelinase to apparent homogeneity by using hydrophobic chromatography. , 1981, The Biochemical journal.
[12] Y. Matsuzawa,et al. Properties of phospholipase C isolated from rat liver lysosomes. , 1980, The Journal of biological chemistry.
[13] A. Bangham,et al. Diffusion of univalent ions across the lamellae of swollen phospholipids. , 1965, Journal of molecular biology.
[14] Y. Matsuzawa,et al. Mechanism of phosphatidylinostiol stimulation of lysosomal bis (monoacylglyceryl)phosphate synthesis. , 1978, The Journal of biological chemistry.
[15] R. Brady,et al. The isolation and characterization of sphingomyelinase from human placental tissue. , 1977, Biochimica et biophysica acta.
[16] H. Shio,et al. Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. III. Intracellular localization of cholesterol and cholesteryl ester. , 1979, Laboratory investigation; a journal of technical methods and pathology.
[17] E. Dennis,et al. Kinetic analysis of phospholipase A2 activity toward mixed micelles and its implications for the study of lipolytic enzymes. , 1975, The Journal of biological chemistry.
[18] P. Dustin,et al. The cellular lesions of Farber's disease and their experimental reproduction in tissue culture. , 1977, Laboratory investigation; a journal of technical methods and pathology.
[19] K. Hostetler,et al. Phospholipase C activity of rat tissues. , 1980, Biochemical and biophysical research communications.
[20] R. Brady,et al. The metabolism of sphingomyelin. I. Purification and properties of a sphingomyelin-cleaving enzyme from rat liver tissue. , 1966, The Journal of biological chemistry.
[21] D. Adler,et al. Regional assignment of the human acid sphingomyelinase gene (SMPD1) by PCR analysis of somatic cell hybrids and in situ hybridization to 11p15.1----p15.4. , 1991, Genomics.
[22] D. Illingworth,et al. Cholesteryl ester hydrolase activity in mononuclear cells from patients with type II hypercholesterolemia. , 1984, Atherosclerosis.
[23] R. E. Pitas,et al. Oxidized low density lipoproteins bind to the scavenger receptor expressed by rabbit smooth muscle cells and macrophages. , 1993, Arteriosclerosis and thrombosis : a journal of vascular biology.
[24] Mojtaba Esfahani,et al. Advances in Cholesterol Research , 1990 .
[25] R. Burrier,et al. Hydrolysis of triolein in phospholipid vesicles and microemulsions by a purified rat liver acid lipase. , 1983, The Journal of biological chemistry.
[26] U. Steinbrecher,et al. Oxidized low density lipoprotein is resistant to cathepsins and accumulates within macrophages. , 1991, The Journal of biological chemistry.
[27] A. Poulos,et al. Additional biochemical findings in a patient and fetal sibling with a genetic defect in the sphingolipid activator protein (SAP) precursor, prosaposin. Evidence for a deficiency in SAP-1 and for a normal lysosomal neuraminidase. , 1992, The Biochemical journal.
[28] W. Stoffel,et al. Studies in vitro on the biosynthesis of ceramide and sphingomyelin. A reevaluation of proposed pathways. , 1980, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
[29] H. W. Cook,et al. Acid and alkaline ceramidases of rat tissues. , 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[30] G. Béréziat,et al. Inhibition of human fibroblasts sphingomyelinase by cholesterol and 7-dehydrocholesterol. , 1981, Biochemical and biophysical research communications.
[31] G. Dallner,et al. Lipid compositions of intracellular membranes isolated from rat liver nodules in Wistar rats. , 1991, Cancer research.
[32] M. W. Spence,et al. Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0. , 1976, Journal of lipid research.
[33] M. Blank. Surface Chemistry of Biological Systems , 1970, Advances in Experimental Medicine and Biology.
[34] M. Krieger,et al. Replacement of neutral lipids of low density lipoprotein with esters of long chain unsaturated fatty acids. , 1979, The Journal of biological chemistry.
[35] S. Gatt. ENZYMIC HYDROLYSIS AND SYNTHESIS OF CERAMIDES. , 1963, The Journal of biological chemistry.
[36] G. Rothblat,et al. Triglyceride and cholesteryl ester hydrolysis in a cell culture model of smooth muscle foam cells. , 1989, Journal of lipid research.
[37] P. Pentchev,et al. Differential accumulation of cholesterol in Golgi compartments of normal and Niemann-Pick type C fibroblasts incubated with LDL: a cytochemical freeze-fracture study. , 1993, Journal of lipid research.
[38] E. Harrison,et al. Hepatic uptake and metabolism of chylomicron retinyl esters: probable role of plasma membrane/endosomal retinyl ester hydrolases. , 1995, Journal of lipid research.
[39] W. Lennarz,et al. Localization of dolichol in the lysosomal fraction of rat liver. , 1982, The Journal of biological chemistry.
[40] A. Tappel,et al. ISOLATION OF RAT-LIVER LYSOSOMES AND THEIR GENERAL PROPERTIES. , 1964, Biochimica et biophysica acta.
[41] R. Franson,et al. LYSOSOMAL PHOSPHOLIPASES A1 AND A2 OF NORMAL AND BACILLUS CALMETTE GUERIN-INDUCED ALVEOLAR MACROPHAGES , 1973, The Journal of cell biology.
[42] K. Sandhoff,et al. Acid sphingomyelinase from human urine: purification and characterization. , 1987, Biochimica et biophysica acta.
[43] K. Suzuki. Enzymatic diagnosis of sphingolipidoses. , 1987, Methods in enzymology.
[44] W. Jerome,et al. Metabolism of cholesteryl ester lipid droplets in a J774 macrophage foam cell model. , 1990, Biochimica et biophysica acta.
[45] T. Suga,et al. Effects of Triton WR-1339 on lipoprotein lipolytic activity and lipid content of rat liver lysosomes. , 1981, Journal of biochemistry.
[46] W. Stoffel,et al. Studies on the biosynthesis of ceramide. Does the reversed ceramidase reaction yield ceramides? , 1980, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
[47] B. Burton,et al. Lysosomal acid lipase in cultivated fibroblasts: characterization of enzyme activity in normal and enzymatically deficient cell lines. , 1980, Clinica chimica acta; international journal of clinical chemistry.
[48] M. Krieger,et al. Replacement of endogenous cholesteryl esters of low density lipoprotein with exogenous cholesteryl linoleate. Reconstitution of a biologically active lipoprotein particle. , 1978, The Journal of biological chemistry.
[49] H. Verheij,et al. Structure and function of phospholiphase A2 , 1981 .
[50] M. Patterson,et al. Progesterone blocks cholesterol translocation from lysosomes. , 1992, The Journal of biological chemistry.
[51] J. Humes,et al. [Identification and characterization of two phospholipase A2 activities in resident mouse peritoneal macrophages]. , 1981, The Biochemical journal.
[52] S. Steinberg,et al. Complementation studies in Niemann-Pick disease type C indicate the existence of a second group. , 1994, Journal of medical genetics.
[53] S. Ohkuma,et al. Characterization of lysosomal acid lipase purified from rabbit liver. , 1984, Journal of biochemistry.
[54] M. Brown,et al. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. , 1983, Annual review of biochemistry.
[55] L. Liscum,et al. The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts , 1989, The Journal of cell biology.
[56] S. Sutrina,et al. Metabolism of ceramide-containing endocytotic vesicles in human diploid fibroblasts. , 1982, The Journal of biological chemistry.
[57] A. Beaudet,et al. Role of lysosomal acid lipase in the metabolism of plasma low density lipoprotein. Observations in cultured fibroblasts from a patient with cholesteryl ester storage disease. , 1975, The Journal of biological chemistry.
[58] R. Anderson,et al. Mutations at the lysosomal acid cholesteryl ester hydrolase gene locus in Wolman disease. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[59] S. Farber,et al. Lipogranulomatosis; a new lipo-glycoprotein storage disease. , 1957, Journal of the Mount Sinai Hospital, New York.
[60] N. Sakuragawa,et al. Partial purification and properties of acid sphingomyelinase from rat liver. , 1983, Journal of lipid research.
[61] H. Griffin,et al. Changes in lipid composition of triton-filled lysosomes during lysis. Association with activation of acid-active lipases and phospholipases. , 1974, Biochimica et biophysica acta.
[62] B. Rosner,et al. CHRONIC RENAL DISEASE , 1975, The Lancet.
[63] Richard G. W. Anderson,et al. Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts , 1977, Cell.
[64] J. Callahan,et al. The active site of lysosomal sphingomyelinase: Evidence for the involvement of hydrophobic and ionic groups , 1983, Journal of neuroscience research.
[65] R. Rousson,et al. Preparation of an anti-acid sphingomyelinase monoclonal antibody for the quantitative determination and polypeptide analysis of lysosomal sphingomyelinase in fibroblasts from normal and Niemann-Pick type A patients. , 1993, Journal of immunological methods.
[66] K. Suzuki,et al. Infantile Niemann-Pick disease. A chemical study with isolation and characterization of membranous cytoplasmic bodies and myelin. , 1969, American journal of diseases of children.
[67] T. Nishide,et al. Effects of chloroquine on the metabolism of phosphatidylcholine associated with low density lipoprotein in arterial smooth muscle cells. , 1989, Atherosclerosis.
[68] M. Schlamowitz,et al. Studies of the use of dihexanoylleithin and other lecithins as substrates for phospholipase A, with addendum on aspects of micelle properties of dihexanoyllecithin. , 1961, Archives of biochemistry and biophysics.
[69] R. Salvayre,et al. Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor- and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts. , 1994, The Biochemical journal.
[70] T. Kleinschmidt,et al. Complete amino-acid sequence of the naturally occurring A2 activator protein for enzymic sphingomyelin degradation: identity to the sulfatide activator protein (SAP-1). , 1988, Biological Chemistry Hoppe-Seyler.
[71] E. Harrison. Enzymes catalyzing the hydrolysis of retinyl esters. , 1993, Biochimica et biophysica acta.
[72] V. Ginsburg. Methods in enzymology Complex carbohydrates. Part E , 1987 .
[73] J. Callahan,et al. Biosynthesis of sphingomyelinase in normal and Niemann-Pick fibroblasts. , 1989, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[74] K. Sandhoff,et al. Intracellular trafficking of glycosphingolipids: Role of sphingolipid activator proteins in the topology of endocytosis and lysosomal digestion , 1994, FEBS letters.
[75] W. A. Bradley,et al. Distinct murine macrophage receptor pathway for human triglyceride-rich lipoproteins. , 1988, The Journal of clinical investigation.
[76] W. Jerome,et al. Early atherogenesis in White Carneau pigeons. II. Ultrastructural and cytochemical observations. , 1985, The American journal of pathology.
[77] G. Decker,et al. Abnormalities of lysosomes in human diploid fibroblasts from patients with Farber's disease. , 1982, Biochimica et biophysica acta.
[78] A. Gown,et al. Immunocytochemical analysis of cellular components in atherosclerotic lesions. Use of monoclonal antibodies with the Watanabe and fat-fed rabbit. , 1986, Arteriosclerosis.
[79] R. Salvayre,et al. Different pathways of uptake and degradation of sphingomyelin by lymphoblastoid cells and the potential participation of the neutral sphingomyelinase. , 1991, The Journal of biological chemistry.
[80] E. Harrison,et al. Inhibitors of neutral cholesteryl ester hydrolase. , 1990, Journal of lipid research.
[81] R. Desnick,et al. Niemann-Pick type B disease. Identification of a single codon deletion in the acid sphingomyelinase gene and genotype/phenotype correlations in type A and B patients. , 1991, The Journal of clinical investigation.
[82] R. Brady,et al. Group C Niemann‐Pick disease: faulty regulation of low‐density lipoprotein uptake and cholesterol storage in cultured fibroblasts , 1987, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[83] J. Wherrett,et al. Formation of bis(monoacylglycero)phosphate by a macrophage transacylase. , 1989, Biochimica et biophysica acta.
[84] R. Ross,et al. Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits. , 1990, Arteriosclerosis.
[85] R. Salvayre,et al. Accurate Differentiation of Neuronopathic and Nonneuronopathic Forms of Niemann‐Pick Disease by Evaluation of the Effective Residual Lysosomal Sphingomyelinase Activity in Intact Cells , 1994, Journal of neurochemistry.
[86] R. Dean,et al. Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages. , 1994, Biochimica et biophysica acta.
[87] S. Erickson,et al. Functional sizes of hepatic enzymes of cholesteryl ester metabolism determined by radiation inactivation. , 1994, Journal of lipid research.
[88] N. Sakuragawa,et al. Reduction of acid sphingomyelinase activity in human fibroblasts induced by AY-9944 and other cationic amphiphilic drugs. , 1985, Journal of biochemistry.
[89] M. Waite. Phospholipases, enzymes that share a substrate class. , 1990, Advances in experimental medicine and biology.
[90] S. Gatt,et al. Effect of Triton X-100 on the hydrolysis of sphingomyelin by sphingomyelinase of rat brain. , 1976, Biochemistry.
[91] G. Brockmann,et al. A 5' splice-region mutation and a dinucleotide deletion in the lysosomal acid lipase gene in two patients with cholesteryl ester storage disease. , 1995, Journal of lipid research.
[92] L. Rosenbaum,et al. Human lysosomal acid lipase/cholesteryl ester hydrolase. Purification and properties of the form secreted by fibroblasts in microcarrier culture. , 1985, The Journal of biological chemistry.
[93] J. Clarke,et al. Pathways of sphingomyelin metabolism in cultured fibroblasts from normal and sphingomyelin lipidosis subjects. , 1983, The Journal of biological chemistry.
[94] T. Peters,et al. LYSOSOMES OF THE ARTERIAL WALL , 1972, The Journal of experimental medicine.
[95] R. Rousson,et al. Abnormal cholesterol metabolism in imipramine-treated fibroblast cultures. Similarities with Niemann-Pick type C disease. , 1990, Biochimica et biophysica acta.
[96] H. Shio,et al. Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. II. Morphometric analysis of lipid-filled lysosomes and lipid droplets in aortic cell populations. , 1978, Laboratory investigation; a journal of technical methods and pathology.
[97] D. Steinberg,et al. A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein. , 1989, The Journal of biological chemistry.
[98] M. Phillips,et al. Physical state of cholesteryl esters deposited in cultured macrophages. , 1988, Biochemistry.
[99] T. Momoi,et al. Substrate-specificities of acid and alkaline ceramidases in fibroblasts from patients with Farber disease and controls. , 1982, The Biochemical journal.
[100] C. Duve,et al. Digestive Activity of Lysosomes , 1968 .
[101] N. Simionescu,et al. Development of intracellular lipid deposits in the lipid-laden cells of atherosclerotic lesions. A cytochemical and ultrastructural study. , 1987, Atherosclerosis.
[102] S. Gatt,et al. Enzymic hydrolysis of sphingomyelin in the presence of bile salts. , 1980, The Biochemical journal.
[103] K. Hostetler,et al. Inhibition of kidney lysosomal phospholipases A and C by aminoglycoside antibiotics: possible mechanism of aminoglycoside toxicity. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[104] D. Small,et al. Production of cholesteryl ester-rich, anisotropic inclusions by mammalian cells in culture. , 1977, Experimental and molecular pathology.
[105] L. Liscum,et al. The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one. , 1989, The Journal of biological chemistry.
[106] A. Beaudet,et al. Human lysosomal sphingomyelinase: substrate efficacy of apolipoprotein/sphingomyelin complexes. , 1986, Biochemistry.
[107] S. Gatt. [24] Enzymatic hydrolysis of sphingolipids , 1969 .
[108] R. Anderson,et al. Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases. , 1991, The Journal of biological chemistry.
[109] R. Winkelmann. The Metabolic Basis of Inherited Diseases , 1972 .
[110] M. Phillips,et al. Lipid composition and physical state effects on cellular cholesteryl ester clearance. , 1984, Journal of Biological Chemistry.
[111] D. Hanahan. Handbook of lipid research , 1978 .
[112] R. Salvayre,et al. Uptake and degradation of several pyrenesphingomyelins by skin fibroblasts from control subjects and patients with Niemann-Pick disease. Effect of the structure of the fluorescent fatty acyl residue. , 1991, The Biochemical journal.
[113] D. Eisen,et al. Inhibition of lysosomal phospholipases C and A in rabbit alveolar macrophages, polymorphonuclear leukocytes and rat liver by sodium bisulfite. , 1984, Biochimica et biophysica acta.
[114] Richard G. W. Anderson,et al. Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins , 1979, The Journal of cell biology.
[115] E. Bohn,et al. Hydrolytic degradation of phosphatidylethanolamine and phosphatidylcholine by isolated rat-liver lysosomes. , 1982, Biochimica et biophysica acta.
[116] A. Beaudet,et al. Apolipoprotein C-III-1 activates lysosomal sphingomyelinase in vitro. , 1981, The Journal of clinical investigation.
[117] R. E. Pitas,et al. Further characterization of the acetyl LDL (scavenger) receptor expressed by rabbit smooth muscle cells and fibroblasts. , 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.
[118] R. Desnick,et al. Structural organization and complete nucleotide sequence of the gene encoding human acid sphingomyelinase (SMPD1). , 1992, Genomics.
[119] K. Hostetler,et al. Chloroquine-induced phospholipid fatty liver. Measurement of drug and lipid concentrations in rat liver lysosomes. , 1985, The Journal of biological chemistry.
[120] B. Trump,et al. Lysosomal degradation of cell organelles. III. Uptake and disappearance in Kupffer cells of intravenously injected isotope-labeled mitochondria and microsomes in vivo and in vitro. , 1975, Laboratory investigation; a journal of technical methods and pathology.
[121] M. Aviram,et al. Oxidized low density lipoprotein leads to macrophage accumulation of unesterified cholesterol as a result of lysosomal trapping of the lipoprotein hydrolyzed cholesteryl ester. , 1994, Journal of lipid research.
[122] W. Weglicki,et al. Phospholipase A activity of lysosomes of rat myocardial tissue. , 1972, Biochemistry.
[123] M. Robinson,et al. Physical-chemical requirements for the catalysis of substrates by lysosomal phospholipase A1. , 1983, The Journal of biological chemistry.
[124] A. Ross,et al. Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035. , 1984, The Journal of biological chemistry.
[125] Y. Barenholz,et al. A spectrophotometric method for determination of sphingomyelinase. , 1978, Biochimica et biophysica acta.
[126] G. Rothblat,et al. Development of the smooth muscle foam cell: uptake of macrophage lipid inclusions. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[127] Y. Hannun,et al. Introduction: sphingolipids and their metabolites in cell regulation. , 1993, Advances in lipid research.
[128] C. de Duve,et al. Digestive activity of lysosomes. I. The digestion of proteins by extracts of rat liver lysosomes. , 1968, The Journal of biological chemistry.
[129] J. Traynor,et al. Phospholipase A2 activity of lysosomal origin secreted by polymorphonuclear leucocytes during phagocytosis or on treatment with calcium. , 1981, Biochimica et biophysica acta.
[130] S. Y. Lee,et al. Studies of inositol phospholipid-specific phospholipase C. , 1989, Science.
[131] C. Duve,et al. Lysosomal acid cholesteryl esterase activity in normal and lipid-laden aortic cells. , 1980, Journal of lipid research.
[132] J. Osada,et al. Isolation of rat liver lysosomes by a single two-phase partition on dextran/polyethylene glycol. , 1990, Analytical biochemistry.
[133] G. Osthoff,et al. Metabolism of phosphatidylglycerol and bis(monoacylglycero)-phosphate in macrophage subcellular fractions. , 1990, The Journal of biological chemistry.
[134] A. Bangham,et al. The relation between the activity of a lecithinase and the electrophoretic charge of the substrate. , 1959, The Biochemical journal.
[135] L. Liscum,et al. A second complementation class of cholesterol transport mutants with a variant Niemann-Pick type C phenotype. , 1994, Journal of lipid research.
[136] P. Kovanen,et al. Mast cell granule remnants carry LDL into smooth muscle cells of the synthetic phenotype and induce their conversion into foam cells. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[137] W. J. Johnson,et al. Formation of cholesterol monohydrate crystals in macrophage-derived foam cells. , 1994, Journal of lipid research.
[138] P. Kovanen,et al. IgE-dependent generation of foam cells: an immune mechanism involving degranulation of sensitized mast cells with resultant uptake of LDL by macrophages. , 1995, Arteriosclerosis, thrombosis, and vascular biology.
[139] W. Jerome,et al. Lysosomal hydrolysis of lipids in a cell culture model of smooth muscle foam cells. , 1991, Experimental and molecular pathology.
[140] M. Brown,et al. The scavenger cell pathway for lipoprotein degradation: specificity of the binding site that mediates the uptake of negatively-charged LDL by macrophages. , 1980, Journal of supramolecular structure.
[141] R. Salvayre,et al. The in situ degradation of ceramide, a potential lipid mediator, is not completely impaired in Farber disease , 1993, FEBS letters.
[142] R. Pagano,et al. Intracellular transport and metabolism of sphingomyelin. , 1991, Biochimica et biophysica acta.
[143] A. Nègre-Salvayre,et al. Cytoplasmic triacylglycerols and cholesteryl esters are degraded in two separate catabolic pools in cultured human fibroblasts , 1993, FEBS letters.
[144] A. Nilsson,et al. The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract. , 1969, Biochimica et biophysica acta.
[145] M. Phillips,et al. Effect of substrate physical state on the activity of acid cholesteryl ester hydrolase. , 1990, Biochimica et biophysica acta.
[146] M. Vanier. Biochemical studies in Niemann-Pick disease. I. Major sphingolipids of liver and spleen. , 1983, Biochimica et Biophysica Acta.
[147] D. Davidson,et al. Studies on the structure of sphingomyelinase. Amino acid composition and heterogeneity on isoelectric focusing. , 1983, The Biochemical journal.
[148] L. Benson,et al. Regulation of the uptake and degradation of beta-very low density lipoprotein in human monocyte macrophages. , 1983, The Journal of biological chemistry.
[149] H. Debuch,et al. The isolation of lysosomes from normal rat liver by affinity chromatography. , 1984, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
[150] H. Glaumann,et al. Autophagy, heterophagy, microautophagy and crinophagy as the means for intracellular degradation , 1981, Virchows Archiv. B, Cell pathology including molecular pathology.
[151] R. Irvine,et al. The hydrolysis of phosphatidylinositol by lysosomal enzymes of rat liver and brain. , 1978, The Biochemical journal.
[152] R. Mahley,et al. Foam Cells in Explants of Atherosclerotic Rabbit Aortas Have Receptors for β‐Very Low Density Low Density Lipoproteins and Modified Low Density Lipoproteins , 1983, Arteriosclerosis.
[153] W. Jerome,et al. Early atherogenesis in the White Carneau pigeon. III. Lipid accumulation in nascent foam cells. , 1987, The American journal of pathology.
[154] R. Salvayre,et al. Acyl-chain specificity and properties of cholesterol esterases from normal and Wolman lymphoid cell lines. , 1987, Biochimica et biophysica acta.
[155] K. Hostetler,et al. Mechanism of cationic amphiphilic drug inhibition of purified lysosomal phospholipase A1. , 1985, Biochemistry.
[156] F. Maxfield,et al. Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages , 1990, The Journal of cell biology.
[157] M. Brown,et al. A receptor-mediated pathway for cholesterol homeostasis. , 1986, Science.
[158] R. Desnick,et al. Toward gene therapy for Niemann-Pick disease (NPD): separation of retrovirally corrected and noncorrected NPD fibroblasts using a novel fluorescent sphingomyelin. , 1992, Human gene therapy.
[159] Arai Hiroyuki,et al. Structure-specific inhibition of lysosomal cholesterol transport in macrophages by various steroids. , 1994 .
[160] R. Paoletti,et al. Advances in Lipid Research , 1988 .
[161] B. Martin,et al. Saposin D: a sphingomyelinase activator. , 1988, Biochemical and biophysical research communications.
[162] N. Radin,et al. Enzymatic formation of hydroxy ceramides and comparison with enzymes forming nonhydroxy ceramides. , 1972, Archives of biochemistry and biophysics.
[163] C. Hornick,et al. Evidence that a neutral cholesteryl ester hydrolase is responsible for the extralysosomal hydrolysis of high‐density lipoprotein cholesteryl ester in rat hepatoma cells (Fu5AH) , 1993, Journal of cellular physiology.
[164] A. Trouet. [31] Isolation of modified liver lysosomes , 1974 .
[165] H. Moser,et al. Role of lysosomal acid ceramidase in the metabolism of ceramide in human skin fibroblasts. , 1981, Archives of biochemistry and biophysics.
[166] D. Davidson,et al. Solid-phase assay for the detection of low-abundance enzymes, and antibodies to enzymes in immune reactions, using acid sphingomyelinase as a model. , 1984, Analytical biochemistry.
[167] R. Munford,et al. Saposin-like proteins (SAPLIP) carry out diverse functions on a common backbone structure. , 1995, Journal of lipid research.
[168] J. Hoeg,et al. Cholesteryl ester storage disease and Wolman disease: phenotypic variants of lysosomal acid cholesteryl ester hydrolase deficiency. , 1984, American journal of human genetics.
[169] D. Steinberg,et al. Enhanced Macrophage Uptake of Low Density Lipoprotein after Self‐Aggregation , 1988, Arteriosclerosis.
[170] I. Ifrim,et al. Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophages , 1995, The Journal of cell biology.
[171] C. Ponting. Acid sphingomyelinase possesses a domain homologous to its activator proteins: Saposins B and D , 1994, Protein science : a publication of the Protein Society.
[172] J. Khoo,et al. Secretion of the lysosomal acid triacylglycerol hydrolase precursor by J774 macrophages. , 1988, Biochimica et biophysica acta.
[173] A. Chait,et al. Phagocytosis of aggregated lipoprotein by macrophages: low density lipoprotein receptor-dependent foam-cell formation. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[174] L. Liscum,et al. Intracellular Cholesterol Transport and Compartmentation (*) , 1995, The Journal of Biological Chemistry.
[175] R. Brady,et al. Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport. , 1991, Developmental neuroscience.
[176] H. Moser,et al. Phenotypic variability in siblings with Farber disease. , 1984, The Journal of pediatrics.
[177] W. Lennarz,et al. The site of biosynthesis and intracellular deposition of dolichol in rat liver. , 1982, The Journal of biological chemistry.
[178] K. Sandhoff,et al. Sphingolipid activator protein D (sap-D) stimulates the lysosomal degradation of ceramide in vivo. , 1994, Biochemical and biophysical research communications.
[179] J. Wherrett,et al. Biosynthesis of bis(monoacylglycero)phosphate in liver and macrophage lysosomes. , 1992, Methods in enzymology.
[180] R. Franson,et al. Identification of phospholipase A 1 and A 2 in the soluble fraction of rat liver lysosomes. , 1971, Biochemistry.
[181] H. Moser,et al. Properties of acid ceramidase from human spleen. , 1989, Biochimica et biophysica acta.
[182] J. Rip,et al. Low-density lipoprotein as a transporter of dolichol intermediates in the mammalian circulation. , 1994, The Biochemical journal.
[183] F. Bernini,et al. Defective catabolism of oxidized LDL by J774 murine macrophages. , 1992, Journal of lipid research.
[184] N. Sakuragawa. Acid sphingomyelinase of human placenta: purification, properties, and 125iodine labeling. , 1982, Journal of biochemistry.
[185] W D Wagner,et al. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. , 1994, Circulation.
[186] J. Cortner,et al. Acid lipase activity of human lymphocytes. , 1979, Biochimica et biophysica acta.
[187] S. Gatt,et al. Enzymatic hydrolysis of sphingolipids. 8. Further purification and properties of rat brain ceramidase. , 1969, Biochemistry.
[188] R. Desnick,et al. Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs. , 1991, The Journal of biological chemistry.
[189] G. Assmann,et al. Accumulation of oxygenated steryl esters in Wolman's disease. , 1975, Journal of lipid research.
[190] K. Sandhoff,et al. The tricyclic antidepressant desipramine causes proteolytic degradation of lysosomal sphingomyelinase in human fibroblasts. , 1994, Biological chemistry Hoppe-Seyler.
[191] L. Liscum,et al. Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts. , 1987, The Journal of biological chemistry.
[192] A. Tanaka. [Acid lipase deficiency (Wolman disease and cholesteryl ester storage disease: CESD)]. , 1998, Ryoikibetsu shokogun shirizu.
[193] G. Shipley,et al. Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques. , 1976, The Journal of clinical investigation.
[194] Sasaki Norihiro,et al. Hydrolysis of low-density lipoprotein phospholipids in arterial smooth muscle cells , 1988 .
[195] M. Aviram. Modified forms of low density lipoprotein and atherosclerosis. , 1993, Atherosclerosis.
[196] J. Lewis,et al. Beta VLDL uptake by pigeon monocyte-derived macrophages: correlation of binding dynamics with three-dimensional ultrastructure. , 1991, Cell motility and the cytoskeleton.
[197] D. Small. The Physical State of Lipids of Biological Importance: Cholesteryl Esters, Cholesterol, Triglyceride , 1970 .
[198] H. Moser,et al. High performance liquid chromatography of ceramides: application to analysis in human tissues and demonstration of ceramide excess in Farber's disease. , 1974, Journal of lipid research.
[199] R. E. Pitas,et al. Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. Up-regulation by phorbol esters. , 1990, The Journal of biological chemistry.
[200] J. Schmitt,et al. Biosynthetic conversion of phosphatidylglycerol to sn-1:sn-1' bis(monoacylglycerol) phosphate in a macrophage-like cell line. , 1995, Biochemistry.
[201] R. Taylor,et al. Lysosomal alterations during coronary atherosclerosis in the pigeon: correlative cytochemical and three-dimensional HVEM/IVEM observations. , 1988, Experimental and molecular pathology.
[202] R. Desnick,et al. Isolation of cDNA clones encoding human acid sphingomyelinase: occurrence of alternatively processed transcripts. , 1989, The EMBO journal.
[203] S. Pelc,et al. FARBER'S DISEASE AS A CERAMIDOSIS: CLINICAL, RADIOLOGICAL AND BIOCHEMICAL ASPECTS , 1978, Acta paediatrica Scandinavica.
[204] H. Moser,et al. Ceramidase and ceramide synthesis in human kidney and cerebellum. Description of a new alkaline ceramidase. , 1975, Biochimica et biophysica acta.
[205] J. Skepper,et al. Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma. , 1995, Atherosclerosis.
[206] W. J. Johnson,et al. The efflux of lysosomal cholesterol from cells. , 1990, The Journal of biological chemistry.
[207] T. Kita,et al. Defective lipoprotein receptors and atherosclerosis. Lessons from an animal counterpart of familial hypercholesterolemia. , 1983, The New England journal of medicine.
[208] D. Richards,et al. Hydrolysis of membrane phospholipids by phospholipases of rat liver lysosomes. , 1979, The Biochemical journal.
[209] C. Hornick,et al. Triacylglycerol hydrolysis in isolated hepatic endosomes. , 1992, The Journal of biological chemistry.
[210] M. Patterson,et al. Ictus emeticus , 1996, Neurology.
[211] S. Gatt. Enzymatic hydrolysis of sphingolipids. I. Hydrolysis and synthesis of ceramides by an enzyme from rat brain. , 1966, The Journal of biological chemistry.
[212] Y. Barenholz,et al. A fluorometric determination of sphingomyelinase by use of fluorescent derivatives of sphingomyelin, and its application to diagnosis of Niemann-Pick disease. , 1980, Clinical chemistry.
[213] J. Wherrett,et al. Lysosomal phosphatidylcholine: bis(monoacylglycero)phosphate acyltransferase: specificity for the sn-1 fatty acid of the donor and co-purification with phospholipase A1. , 1993, Biochimica et biophysica acta.
[214] G. Rothblat,et al. Cholesteryl ester cycle in cultured hepatoma cells. , 1987, Atherosclerosis.
[215] P. Kovanen. Mast cell granule-mediated uptake of low density lipoproteins by macrophages: a novel carrier mechanism leading to the formation of foam cells. , 1991, Annals of medicine.
[216] P. Ghosh,et al. Effects of gentamicin on sphingomyelinase activity in cultured human renal proximal tubular cells. , 1987, The Journal of biological chemistry.
[217] Bell Rm,et al. Ceramidases: enzymology and metabolic roles. , 1993, Advances in lipid research.
[218] R. Pagano,et al. Sorting of an internalized plasma membrane lipid between recycling and degradative pathways in normal and Niemann-Pick, type A fibroblasts , 1990, The Journal of cell biology.
[219] W. J. Johnson,et al. Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides. , 1995, Biochemistry.
[220] S. Srinivasan,et al. Complexes of low-density lipoproteins and arterial proteoglycan aggregates promote cholesteryl ester accumulation in mouse macrophages. , 1985, Biochimica et biophysica acta.
[221] N. Le,et al. Apo E-mediated uptake and degradation of normal very low density lipoproteins by human monocyte/macrophages: a saturable pathway distinct from the LDL receptor. , 1985, Biochemical and biophysical research communications.
[222] C. Duve,et al. Lysosomes of the arterial wall: II. Subcellular fractionation of aortic cells from rabbits with Experimental Atheroma , 1974 .
[223] Kunihiko Suzuki,et al. Acid Sphingomyelinase of Human Brain: Purification to Homogeneity , 1982, Journal of neurochemistry.
[224] F. Leighton,et al. THE LARGE-SCALE SEPARATION OF PEROXISOMES, MITOCHONDRIA, AND LYSOSOMES FROM THE LIVERS OF RATS INJECTED WITH TRITON WR-1339 , 1968, The Journal of cell biology.
[225] R. Tangirala,et al. Lysosomal accumulation of unesterified cholesterol in model macrophage foam cells. , 1993, The Journal of biological chemistry.
[226] K. Hostetler,et al. Purification of lysosomal phospholipase A. Evidence for multiple isoenzymes in rat liver. , 1982, The Journal of biological chemistry.
[227] R. Brady,et al. Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[228] Y. Hannun,et al. The sphingomyelin cycle and the second messenger function of ceramide. , 1994, The Journal of biological chemistry.
[229] M. Brown,et al. The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters. , 1980, The Journal of biological chemistry.
[230] L. Liscum,et al. Intracellular cholesterol transport. , 1992, Journal of lipid research.
[231] M. Brown,et al. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[232] H. Moser,et al. Ceramide and Ganglioside Accumulation in Farber's Lipogranulomatosis.∗ , 1967 .
[233] W. J. Johnson,et al. Cell Toxicity Induced by Inhibition of Acyl Coenzyme A:Cholesterol Acyltransferase and Accumulation of Unesterified Cholesterol * , 1995, The Journal of Biological Chemistry.
[234] H. Heidrich,et al. The phospholipids of liver lysosomes from untreated rats. , 1980, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
[235] H. Moser,et al. PRENATAL DIAGNOSIS OF FARBER'S DISEASE , 1979, The Lancet.
[236] C. Deduve. The participation of lysosomes in the transformation of smooth muscle cells to foamy cells in the aorta of cholesterol-fed rabbits. , 1974 .
[237] T. V. van Berkel,et al. Characteristics of acid lipase and acid cholesteryl esterase activity in parenchymal and non-parenchymal rat liver cells. , 1980, Biochimica et biophysica acta.