A bivariate power generalized Weibull distribution: A flexible parametric model for survival analysis

We are concerned with the flexible parametric analysis of bivariate survival data. Elsewhere, we argued in favour of an adapted form of the ‘power generalized Weibull’ distribution as an attractive vehicle for univariate parametric survival analysis. Here, we additionally observe a frailty relationship between a power generalized Weibull distribution with one value of the parameter which controls distributional choice within the family and a power generalized Weibull distribution with a smaller value of that parameter. We exploit this relationship to propose a bivariate shared frailty model with power generalized Weibull marginal distributions linked by the BB9 or ‘power variance function’ copula, then change it to have adapted power generalized Weibull marginals in the obvious way. The particular choice of copula is, therefore, natural in the current context, and the corresponding bivariate adapted power generalized Weibull model a novel combination of pre-existing components. We provide a number of theoretical properties of the models. We also show the potential of the bivariate adapted power generalized Weibull model for practical work via an illustrative example involving a well-known retinopathy dataset, for which the analysis proves to be straightforward to implement and informative in its outcomes.

[1]  P. Hougaard Survival models for heterogeneous populations derived from stable distributions , 1986 .

[2]  M. C. Jones,et al.  A flexible parametric modelling framework for survival analysis , 2019, Journal of the Royal Statistical Society: Series C (Applied Statistics).

[3]  Pushpa L. Gupta,et al.  Ageing Characteristics of the Weibull Mixtures , 1996 .

[4]  Bill Ravens,et al.  An Introduction to Copulas , 2000, Technometrics.

[5]  M. L. Lakhal-Chaieb Copula inference under censoring , 2010 .

[6]  José S. Romeo,et al.  Bayesian bivariate survival analysis using the power variance function copula , 2018, Lifetime data analysis.

[7]  D. Clayton A model for association in bivariate life tables and its application in epidemiological studies of familial tendency in chronic disease incidence , 1978 .

[8]  Satishs Iyengar,et al.  Multivariate Models and Dependence Concepts , 1998 .

[9]  M. Weibull,et al.  A Multivariate Distribution with Weibull Connections , 1989 .

[10]  James R. Kenyon,et al.  Analysis of Multivariate Survival Data , 2002, Technometrics.

[11]  P. Embrechts,et al.  Dependence modeling with copulas , 2007 .

[12]  David Beaudoin,et al.  IPCW Estimator for Kendall's Tau under Bivariate Censoring , 2009 .

[13]  Mikhail Nikulin,et al.  On the power generalizedWeibull family: model for cancer censored data , 2009 .

[14]  Johann Sölkner,et al.  Frailty Models in Survival Analysis , 1996 .

[15]  M. C. Jones,et al.  Log-location-scale-log-concave distributions for survival and reliability analysis , 2015 .

[16]  Paul Janssen,et al.  Frailty Model , 2007, International Encyclopedia of Statistical Science.

[17]  Theodora Dimitrakopoulou,et al.  A Lifetime Distribution With an Upside-Down Bathtub-Shaped Hazard Function , 2007, IEEE Transactions on Reliability.

[18]  M. Fischer,et al.  pTAS distributions with application to risk management , 2016, Journal of Statistical Distributions and Applications.

[19]  D. Oakes,et al.  Bivariate survival models induced by frailties , 1989 .

[20]  R Brookmeyer,et al.  Modelling paired survival data with covariates. , 1989, Biometrics.