Fine Needle Aspiration Biopsy in Central Giant Cell Lesion

Background Fine needle aspiration biopsy (FNAB) is a safe and efficient diagnostic method used in numerous lesions of the head and neck region. However, its use in central giant cell lesion (CGCL) is rarely seen. Cases Three cases of CGCL were initially diagnosed with FNAB, emphasizing the cytologic and immunocytochemical features. Conclusion FNAB, particularly when associated with clinical, radiographic and laboratory examinations, plays an important role in the preliminary diagnosis of CGCL.

[1]  P. Dey,et al.  Comparison of cytologic features of giant‐cell tumor and giant‐cell tumor of tendon sheath , 2004, Diagnostic cytopathology.

[2]  J. Regezi Comments on the pathogenesis and medical treatment of central giant cell granulomas. , 2004, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[3]  Shi-feng Yu,et al.  Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. , 2003, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[4]  M. Pogrel Calcitonin therapy for central giant cell granuloma. , 2003, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[5]  D. Carter Tumors and Cysts of the Jaws: Atlas of Tumor Pathology, Third Series, Fascicle 29. , 2002 .

[6]  R. Carlos,et al.  Intralesional corticosteroids as an alternative treatment for central giant cell granuloma. , 2002, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[7]  J. Sciubba Tumors and cysts of the jaws , 2001 .

[8]  A. ozveren,et al.  Fine needle aspiration biopsy (FNAB) in fibrous and non-fibrous soft oral tissue lesions. , 1999, Journal of oral science.

[9]  R. Gomez,et al.  Immunocytochemistry of fine-needle aspirates from central giant cell granuloma. , 1998, The British journal of oral & maxillofacial surgery.

[10]  Y. Kaw Fine needle aspiration cytology of central giant cell granuloma of the jaw. A report of two cases. , 1994, Acta cytologica.

[11]  C. Waldron,et al.  Giant cell lesions of the maxilla and paranasal sinuses , 1994, Head & neck.

[12]  C. Waldron,et al.  Central giant cell lesions of the jaws. A clinical, radiologic, and histopathologic study. , 1993, Oral surgery, oral medicine, and oral pathology.

[13]  I. Ramzy,et al.  Diagnosis of radiolucent lesions of the jaw by fine needle aspiration biopsy. , 1985, Acta cytologica.

[14]  H. Jaffe Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-osseous) dysplasia of the jawbones , 1953 .

[15]  H. Jaffe Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-oseous) dysplasia of the jawbones. , 1953, Oral surgery, oral medicine, and oral pathology.