Incorporating virtual reality graphics with brain imaging for assessment of sport-related concussions

There is a growing concern that traditional neuropsychological (NP) testing tools are not sensitive to detecting residual brain dysfunctions in subjects suffering from mild traumatic brain injuries (MTBI). Moreover, most MTBI patients are asymptomatic based on anatomical brain imaging (CT, MRI), neurological examinations and patients' subjective reports within 10 days post-injury. Our ongoing research has documented that residual balance and visual-kinesthetic dysfunctions along with its underlying alterations of neural substrates may be detected in “asymptomatic subjects” by means of Virtual Reality (VR) graphics i ncorporated with brain imaging (EEG) techniques.

[1]  D. Pennell,et al.  Functional abnormalities in normally appearing athletes following mild traumatic brain injury: a functional MRI study , 2010, Experimental Brain Research.

[2]  L. Stovner,et al.  Magnetic resonance imaging after most common form of concussion , 2009, BMC Medical Imaging.

[3]  T. Baumgartner,et al.  Virtual Reality and the Role of the Prefrontal Cortex in Adults and Children , 2009, Frontiers in neuroscience.

[4]  K. Ukai,et al.  Effects of visually simulated roll motion on vection and postural stabilization , 2007, Journal of NeuroEngineering and Rehabilitation.

[5]  Nicholas Stergiou,et al.  Recovery of postural control after cerebral concussion: new insights using approximate entropy. , 2006, Journal of athletic training.

[6]  Hiroshi Shibasaki,et al.  Neural underpinning of postural responses to visual field motion , 2006, Biological Psychology.

[7]  Karl M. Newell,et al.  Application of Virtual Reality Graphics in Assessment of Concussion , 2006, Cyberpsychology Behav. Soc. Netw..

[8]  Semyon Slobounov,et al.  EEG and postural correlates of mild traumatic brain injury in athletes , 2005, Neuroscience Letters.

[9]  M. Hallett,et al.  Role of cerebral cortex in human postural control: an EEG study , 2005, Clinical Neurophysiology.

[10]  Arnaud Delorme,et al.  EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis , 2004, Journal of Neuroscience Methods.

[11]  K. Guskiewicz.  Assessment of postural stability following sport-related concussion. , 2003, Current sports medicine reports.

[12]  E. Maguire,et al.  The Human Hippocampus and Spatial and Episodic Memory , 2002, Neuron.

[13]  Andrew J. Saykin,et al.  Differential Working Memory Load Effects after Mild Traumatic Brain Injury , 2001, NeuroImage.

[14]  S. Slobounov,et al.  Neurophysiological and behavioral indices of time pressure effects on visuomotor task performance. , 2000, Brain research. Cognitive brain research.

[15]  Emily A Keshner,et al.  Field of view and base of support width influence postural responses to visual stimuli during quiet stance. , 2007, Gait & posture.

[16]  Alain Ptito,et al.  Contributions of functional magnetic resonance imaging (fMRI) to sport concussion evaluation. , 2007, NeuroRehabilitation.

[17]  M. Hallett,et al.  Neural basis subserving the detection of postural instability: an fMRI study. , 2006, Motor control.

[18]  Robert C. Cantu,et al.  Concussion Classification: Ongoing Controversy , 2006 .