Psychosocial treatments for schizophrenia.

The current state of the literature regarding psychosocial treatments for schizophrenia is reviewed within the frameworks of the recovery model of mental health and the expanded stress-vulnerability model. Interventions targeting specific domains of functioning, age groups, stages of illness, and human service system gaps are classified as evidence-based practices or promising practices according to the extent to which their efficacy is currently supported by meta-analyses and individual randomized controlled trials (RCTs). Evidence-based practices include assertive community treatment (ACT), cognitive behavior therapy (CBT) for psychosis, cognitive remediation, family psychoeducation, illness self-management training, social skills training, and supported employment. Promising practices include cognitive adaptive therapy, CBT for posttraumatic stress disorder, first-episode psychosis intervention, healthy lifestyle interventions, integrated treatment for co-occurring disorders, interventions targeting older individuals, peer support services, physical disease management, prodromal stage intervention, social cognition training, supported education, and supported housing. Implications and future directions are discussed.

[1]  D. Roe,et al.  A randomized controlled trial of the effectiveness of the illness management and recovery program. , 2007, Psychiatric services.

[2]  K. Mueser,et al.  Cognitive Behavior Therapy for Psychosis: A Call to Action , 2006 .

[3]  G. Hogarty,et al.  Three-year trials of personal therapy among schizophrenic patients living with or independent of family, II: Effects on adjustment of patients. , 1997, The American journal of psychiatry.

[4]  B. Mausbach,et al.  Functional Adaptation Skills Training (FAST): A randomized trial of a psychosocial intervention for middle-aged and older patients with chronic psychotic disorders , 2006, Schizophrenia Research.

[5]  J. Hooley Expressed emotion and relapse of psychopathology. , 2007, Annual review of clinical psychology.

[6]  D. Kingdon Over-simplification and exclusion of non-conforming studies can demonstrate absence of effect: a lynching party? , 2009, Psychological Medicine.

[7]  M. Farkas The vision of recovery today: what it is and what it means for services. , 2007, World psychiatry : official journal of the World Psychiatric Association.

[8]  R. Liberman,et al.  Attention shaping: a reward-based learning method to enhance skills training outcomes in schizophrenia. , 2009, Schizophrenia bulletin.

[9]  G. Hogarty Personal Therapy for Schizophrenia and Related Disorders: A Guide to Individualized Treatment , 2002 .

[10]  A. Rudnick,et al.  Combining supported education with supported employment. , 2009, Psychiatric services.

[11]  K H Nuechterlein,et al.  A heuristic vulnerability/stress model of schizophrenic episodes. , 1984, Schizophrenia bulletin.

[12]  S. Segal,et al.  Empowerment and self-help agency practice for people with mental disabilities. , 1993, Social work.

[13]  S. Bartels,et al.  Integrated Illness Management and Recovery: A Program for Integrating Physical and Psychiatric Illness Self-Management in Older Persons with Severe Mental Illness , 2012 .

[14]  W. McFarlane Multifamily Groups in the Treatment of Severe Psychiatric Disorders , 2002 .

[15]  D. Roe,et al.  Beyond coping with mental illness: toward personal growth. , 2003, The American journal of orthopsychiatry.

[16]  S. Rosenberg,et al.  Cognitive-Behavioral Treatment of PTSD in Severe Mental Illness: Pilot Study Replication in an Ethnically Diverse Population , 2009 .

[17]  R. Drake,et al.  An update on randomized controlled trials of evidence-based supported employment. , 2008, Psychiatric rehabilitation journal.

[18]  J. Strauss,et al.  Prediction of outcome in schizophrenia. III. Five-year outcome and its predictors. , 1977, Archives of general psychiatry.

[19]  A. Morrison Cognitive behaviour therapy for first episode psychosis: Good for nothing or fit for purpose? , 2009 .

[20]  David L. Roberts,et al.  The functional significance of social cognition in schizophrenia: a review. , 2006, Schizophrenia bulletin.

[21]  I. Olkin,et al.  Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement , 1999, The Lancet.

[22]  E. Granholm,et al.  A randomized, controlled trial of cognitive behavioral social skills training for middle-aged and older outpatients with chronic schizophrenia. , 2005, The American journal of psychiatry.

[23]  S. Rosenberg,et al.  Trauma, PTSD, and the course of severe mental illness: an interactive model , 2002, Schizophrenia Research.

[24]  R. Drake,et al.  Implementing evidence-based practices for people with schizophrenia. , 2009, Schizophrenia bulletin.

[25]  B. Pepper,et al.  The young adult chronic patient: overview of a population. , 1981, Hospital & community psychiatry.

[26]  B. Druss,et al.  Quality of medical care and excess mortality in older patients with mental disorders. , 2001, Archives of general psychiatry.

[27]  Amy N. Cohen,et al.  The family forum: directions for the implementation of family psychoeducation for severe mental illness. , 2008, Psychiatric services.

[28]  A. Jablensky The 100-year epidemiology of schizophrenia , 1997, Schizophrenia Research.

[29]  R. Kessler,et al.  The economic burden of schizophrenia in the United States in 2002. , 2005, The Journal of clinical psychiatry.

[30]  Michelle Cleary,et al.  Psychosocial interventions for people with both severe mental illness and substance misuse. , 2013, The Cochrane database of systematic reviews.

[31]  K. Mueser,et al.  An Assessment of the Educational Needs of Chronic Psychiatric Patients and their Relatives , 1992, British Journal of Psychiatry.

[32]  Suresh Bada Math,et al.  Learning Cognitive-behavior Therapy: An Illustrated Guide , 2017 .

[33]  T. Lincoln,et al.  Effectiveness of psychoeducation for relapse, symptoms, knowledge, adherence and functioning in psychotic disorders: A meta-analysis , 2007, Schizophrenia Research.

[34]  P. McGorry,et al.  Implementing Early Intervention in Psychosis: A Guide to Establishing Psychosis Services , 2002 .

[35]  E. Granholm,et al.  Social disinterest attitudes and group cognitive-behavioral social skills training for functional disability in schizophrenia. , 2009, Schizophrenia bulletin.

[36]  E. Susser,et al.  A Randomized Trial of Critical Time Intervention to Prevent Homelessness in Persons with Severe Mental Illness following Institutional Discharge , 2011 .

[37]  L. Egede,et al.  Trauma exposure and posttraumatic stress disorder in adults with severe mental illness: a critical review. , 2011, Clinical psychology review.

[38]  J. Os,et al.  The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: A meta-analysis , 2011, Neuroscience & Biobehavioral Reviews.

[39]  T. Wykes,et al.  Cognitive Remediation Therapy for Schizophrenia : Theory and Practice , 2006 .

[40]  Jane S. Paulsen,et al.  Neuropsychological deficits in schizophrenics. Relationship to age, chronicity, and dementia. , 1994, Archives of general psychiatry.

[41]  I. Olkin,et al.  Improving the quality of reports of meta‐analyses of randomised controlled trials: the QUOROM statement , 2000, Revista espanola de salud publica.

[42]  J. Cook,et al.  Results of a randomized controlled trial of mental illness self-management using Wellness Recovery Action Planning. , 2012, Schizophrenia bulletin.

[43]  Robert E. Drake,et al.  Treating Homeless Clients with Severe Mental Illness and Substance Use Disorders: Costs and Outcomes , 2006, Community Mental Health Journal.

[44]  Michelle Cleary,et al.  Psychosocial interventions for people with both severe mental illness and substance misuse. , 2013, The Cochrane database of systematic reviews.

[45]  P. McGorry,et al.  Vocational intervention in first-episode psychosis: Individual placement and support v. treatment as usual , 2008, British Journal of Psychiatry.

[46]  W. Heiden,et al.  Course and Outcome , 2011 .

[47]  S. Gutman,et al.  Supported education for adults with psychiatric disabilities: effectiveness of an occupational therapy program. , 2009, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[48]  Susan Cooley,et al.  Cognitive enhancement therapy for schizophrenia: effects of a 2-year randomized trial on cognition and behavior. , 2004, Archives of general psychiatry.

[49]  K. Mueser,et al.  Social skills and social functioning. , 1998 .

[50]  J. Bisson,et al.  Psychological treatment of post-traumatic stress disorder (PTSD). , 2007, The Cochrane database of systematic reviews.

[51]  P. Buckley,et al.  Treatment-refractory schizophrenia , 2001, Current psychiatry reports.

[52]  R. Drake,et al.  Individual placement and support for individuals with recent-onset schizophrenia: integrating supported education and supported employment. , 2008, Psychiatric rehabilitation journal.

[53]  R. Drake,et al.  A Working Life for People with Severe Mental Illness , 2001 .

[54]  D S Rae,et al.  Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. , 1990, JAMA.

[55]  R. Drake,et al.  Assertive community treatment for patients with co-occurring severe mental illness and substance use disorder: a clinical trial. , 1998, The American journal of orthopsychiatry.

[56]  D. Kavanagh,et al.  Current evidence on integrated treatment for serious mental disorder and substance misuse , 2007 .

[57]  R. Kessler,et al.  Posttraumatic stress disorder in the National Comorbidity Survey. , 1995, Archives of general psychiatry.

[58]  S. Kanba,et al.  Prediction of medication noncompliance in outpatients with schizophrenia: 2-year follow-up study , 2006, Psychiatry Research.

[59]  B. Druss,et al.  The Health and Recovery Peer (HARP) Program: A peer-led intervention to improve medical self-management for persons with serious mental illness , 2010, Schizophrenia Research.

[60]  S. Bartels,et al.  Medicare and medicaid costs for schizophrenia patients by age cohort compared with costs for depression, dementia, and medically ill patients. , 2003, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[61]  R. Drake,et al.  Work and nonvocational domains of functioning in persons with severe mental illness: a longitudinal analysis. , 1997, The Journal of nervous and mental disease.

[62]  R. Drake,et al.  New Hampshire's specialized services for the dually diagnosed. , 1991, New directions for mental health services.

[63]  Michael F. Green,et al.  Social Cognition Training for Individuals with Schizophrenia: Emerging Evidence , 2008 .

[64]  M. Chernick,et al.  Randomized controlled trial of illness management and recovery in multiple-unit supportive housing. , 2009, Psychiatric services.

[65]  J. McGrath,et al.  Why schizophrenia epidemiology needs neurobiology--and vice versa. , 2009, Schizophrenia bulletin.

[66]  I. Cormac,et al.  WITHDRAWN: Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia. , 2011, The Cochrane database of systematic reviews.

[67]  A. Aleman,et al.  Cognitive rehabilitation in schizophrenia: a quantitative analysis of controlled studies , 2003, Psychopharmacology.

[68]  R. Kessler,et al.  Social consequences of psychiatric disorders, I: Educational attainment. , 1995, The American journal of psychiatry.

[69]  E. Twamley,et al.  A meta-analysis of cognitive remediation in schizophrenia. , 2007, The American journal of psychiatry.

[70]  M. Harrow,et al.  Negative symptoms in schizophrenia: their longitudinal course and prognostic importance. , 1985, Schizophrenia bulletin.

[71]  L. Motlová Schizophrenia and family. , 2007, Neuro endocrinology letters.

[72]  Larry Davidson,et al.  Effectiveness of peer support in reducing readmissions of persons with multiple psychiatric hospitalizations. , 2011, Psychiatric services.

[73]  Emil Kraepelin,et al.  Dementia praecox and paraphrenia , 2002 .

[74]  R. Drake,et al.  A review of research on residential programs for people with severe mental illness and co-occurring substance use disorders. , 2004, Drug and alcohol review.

[75]  S. McGurk,et al.  Cognitive functioning, symptoms, and work in supported employment: a review and heuristic model , 2004, Schizophrenia Research.

[76]  Richie Poulton,et al.  Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: a 30-year study. , 2010, The American journal of psychiatry.

[77]  R. Drake,et al.  Use of Integrated Dual Disorder Treatment Via Assertive Community Treatment Versus Clinical Case Management for Persons With Co-Occurring Disorders and Antisocial Personality Disorder , 2009, The Journal of nervous and mental disease.

[78]  P. Garety,et al.  Cognitive Behaviour Therapy for Psychosis: Theory and Practice , 1999 .

[79]  K. Lorig,et al.  A disease-specific self-help program compared with a generalized chronic disease self-help program for arthritis patients. , 2005, Arthritis and rheumatism.

[80]  Vyv Huddy,et al.  A Meta-Analysis of Cognitive Remediation for Schizophrenia: Methodology and Effect Sizes , 2012 .

[81]  S. Bartels,et al.  Randomized trial of social rehabilitation and integrated health care for older people with severe mental illness. , 2010, Journal of consulting and clinical psychology.

[82]  P. Links,et al.  The relationship between personality disorders and Axis I psychopathology: deconstructing comorbidity. , 2013, Annual review of clinical psychology.

[83]  S. Bartels,et al.  Are Nursing Homes Appropriate for Older Adults with Severe Mental Illness? Conflicting Consumer and Clinician Views and Implications for the Olmstead Decision , 2003, Journal of the American Geriatrics Society.

[84]  N. Tarrier,et al.  Integrated motivational interviewing and cognitive behavioural therapy for people with psychosis and comorbid substance misuse: randomised controlled trial , 2010, BMJ : British Medical Journal.

[85]  Janice,et al.  A randomized single-blind pilot study of compensatory strategies in schizophrenia outpatients. , 2002, Schizophrenia bulletin.

[86]  R. Drake,et al.  Recent Advances in Psychiatric Rehabilitation for Patients with Severe Mental Illness , 1997, Harvard review of psychiatry.

[87]  Heinz Häfner,et al.  Modeling the early course of schizophrenia. , 2003, Schizophrenia bulletin.

[88]  Nicholas Tarrier,et al.  Illness Management and Recovery: A Review of the Research , 2002 .

[89]  C. Wallace,et al.  Enlisting indigenous community supporters in skills training programs for persons with severe mental illness. , 2000, Psychiatric services.

[90]  D. Streiner,et al.  Family intervention for schizophrenia. , 2003, The Cochrane database of systematic reviews.

[91]  K. Gill,et al.  The concept of "being in recovery". , 2007, Psychiatric rehabilitation journal.

[92]  L. Davidson,et al.  Peer support among adults with serious mental illness: a report from the field. , 2005, Schizophrenia bulletin.

[93]  R. Liberman,et al.  Supplementing clinic-based skills training with manual-based community support sessions: effects on social adjustment of patients with schizophrenia. , 2002, The American journal of psychiatry.

[94]  A. Beck Successful outpatient psychotherapy of a chronic schizophrenic with a delusion based on borrowed guilt. , 1952, Psychiatry.

[95]  N. Tarrier,et al.  Supportive therapy for schizophrenia: possible mechanisms and implications for adjunctive psychosocial treatments. , 2004, Schizophrenia bulletin.

[96]  S. Schmidt,et al.  Effectiveness of integrated psychological therapy (IPT) for schizophrenia patients: a research update. , 2011, Schizophrenia bulletin.

[97]  G. Krarup,et al.  Five-year follow-up of a randomized multicenter trial of intensive early intervention vs standard treatment for patients with a first episode of psychotic illness: the OPUS trial. , 2008, Archives of general psychiatry.

[98]  B. Druss,et al.  A randomized trial of medical care management for community mental health settings: the Primary Care Access, Referral, and Evaluation (PCARE) study. , 2010, The American journal of psychiatry.

[99]  R. Drake,et al.  Psychosocial Interventions for Adults with Severe Mental Illnesses and Co-Occurring Substance Use Disorders , 2005 .

[100]  C. Wallace,et al.  Training skills in the psychiatrically disabled: learning coping and competence. , 1986, Schizophrenia bulletin.

[101]  D. Karp The Burden of Sympathy: How Families Cope With Mental Illness , 2000 .

[102]  B. Barraclough,et al.  Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia , 1998, British Journal of Psychiatry.

[103]  G. Faulkner,et al.  Exercise therapy for schizophrenia. , 2010, The Cochrane database of systematic reviews.

[104]  P. McGorry,et al.  Non-pharmacological management of antipsychotic-induced weight gain: Systematic review and meta-analysis of randomised controlled trials , 2008, British Journal of Psychiatry.

[105]  J. Cook,et al.  Randomized controlled trial of peer-led recovery education using Building Recovery of Individual Dreams and Goals through Education and Support (BRIDGES) , 2012, Schizophrenia Research.

[106]  J. Lieberman,et al.  Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. , 2005, The New England journal of medicine.

[107]  B. Morenz Learning Cognitive- Behavior Therapy: An Illustrated Guide , 2007 .

[108]  J. Chamberlin On Our Own: Patient-Controlled Alternatives to the Mental Health System , 1979 .

[109]  M. Birchwood,et al.  Management of first-episode psychosis , 2001 .

[110]  N. Tarrier,et al.  Trauma and comorbid posttraumatic stress disorder in individuals with schizophrenia and substance abuse. , 2011, Comprehensive psychiatry.

[111]  Glenn Roberts Principles and Practice of Psychiatric Rehabilitation : An Empirical Approach , 2007, British Journal of Psychiatry.

[112]  G. L. Paul,et al.  Psychosocial Treatment of Chronic Mental Patients: Milieu Versus Social-Learning Programs , 1977 .

[113]  Kimberly L. Goodman,et al.  Principles underlying the use of multiple informants' reports. , 2013, Annual review of clinical psychology.

[114]  E. Leete How I perceive and manage my illness. , 1989, Schizophrenia bulletin.

[115]  S. Bartels,et al.  Psychosocial Rehabilitation in Older Adults with Serious Mental Illness: A Review of the Research Literature and Recommendations for Development of Rehabilitative Approaches , 2008 .

[116]  H. Remschmidt,et al.  Childhood-onset schizophrenia: history of the concept and recent studies. , 1994, Schizophrenia bulletin.

[117]  Craig Whittington,et al.  Early intervention services, cognitive–behavioural therapy and family intervention in early psychosis: systematic review , 2010, British Journal of Psychiatry.

[118]  T. O’Hare,et al.  Subjective Distress Associated with Sudden Loss in Clients with Severe Mental Illness , 2011, Community Mental Health Journal.

[119]  D. Polcin Issues in the treatment of dual diagnosis clients who have chronic mental illness , 1992 .

[120]  J. Adler,et al.  Living into the story: agency and coherence in a longitudinal study of narrative identity development and mental health over the course of psychotherapy. , 2012, Journal of personality and social psychology.

[121]  K. Unger Handbook on Supported Education: Providing Services for Students With Psychiatric Disabilities , 1998 .

[122]  K. Mueser,et al.  Prediction of social skill acquisition in schizophrenic and major affective disorder patients from memory and symptomatology , 1991, Psychiatry Research.

[123]  G. Teague,et al.  The TMACT: A New Tool for Measuring Fidelity to Assertive Community Treatment , 2011, Journal of the American Psychiatric Nurses Association.

[124]  N. de Lacy,et al.  Revisiting the relationship between autism and schizophrenia: toward an integrated neurobiology. , 2013, Annual review of clinical psychology.

[125]  D. Charney,et al.  Discovering the neural basis of human social anxiety: a diagnostic and therapeutic imperative. , 2004, The American journal of psychiatry.

[126]  S. Newman,et al.  Self-management interventions for chronic illness , 2004, The Lancet.

[127]  H. Möller,et al.  Early detection and secondary prevention of psychosis: facts and visions* , 2004, European Archives of Psychiatry and Clinical Neuroscience.

[128]  M. Kimble,et al.  Cognitive-Behavioral Treatment for PTSD Among People with Severe Mental Illness: A Proposed Treatment Model , 2004, Journal of psychiatric practice.

[129]  T. Lidz,et al.  Schizophrenia and the family. , 1958, Psychiatry.

[130]  R. Drake,et al.  Integrated Treatment for Dual Disorders: A Guide to Effective Practice , 2003 .

[131]  C. Williams Assertive outreach in mental healthcare : current perspectives , 2011 .

[132]  Nancy H. Covell,et al.  Comparison of ACT and standard case management for delivering integrated treatment for co-occurring disorders. , 2006, Psychiatric services.

[133]  M. Kurtz,et al.  Social cognitive training for schizophrenia: a meta-analytic investigation of controlled research. , 2012, Schizophrenia bulletin.

[134]  Betty Pfefferbaum,et al.  Guideline for the treatment of patients with acute stress disorder and posttraumatic stress disorder , 2004 .

[135]  M. Kessler Will social phobia subjects answer the telephone? , 1995, The American journal of psychiatry.

[136]  R. Jorge,et al.  Posttraumatic Stress Disorder , 2015, Continuum.

[137]  Nathan H. Azrin,et al.  The Token Economy: A Motivational System for Therapy and Rehabilitation , 1968 .

[138]  D. Penn,et al.  Evaluation of a multi-element treatment center for early psychosis in the United States , 2012, Social Psychiatry and Psychiatric Epidemiology.

[139]  R. Liberman Psychosocial treatments for schizophrenia. , 1994, Psychiatry.

[140]  R. Kessler,et al.  Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey. , 1997, Archives of general psychiatry.

[141]  Michael F. Green,et al.  What are the functional consequences of neurocognitive deficits in schizophrenia? , 1996, The American journal of psychiatry.

[142]  P. Liddle Schizophrenic syndromes, cognitive performance and neurological dysfunction , 1987, Psychological Medicine.

[143]  R. Bentall,et al.  Cognitive Therapy for Psychosis: A Formulation-Based Approach , 2004 .

[144]  R. Drake,et al.  Complications of severe mental illness related to alcohol and drug use disorders. , 1998, Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism.

[145]  J. De Maeseneer,et al.  Effectiveness and cost-effectiveness of lifestyle interventions on physical activity and eating habits in persons with severe mental disorders: A systematic review , 2011, The international journal of behavioral nutrition and physical activity.

[146]  Stephen Joseph,et al.  Positive psychology: Past, present, and (possible) future , 2006 .

[147]  Keith R. Stowell,et al.  Principles and Practice of Psychiatric Rehabilitation: An Empirical Approach , 2008 .

[148]  Michael F. Green,et al.  Social cognition in schizophrenia , 2015, Nature Reviews Neuroscience.

[149]  Robert Rosenheck,et al.  Cost-effectiveness of supported housing for homeless persons with mental illness. , 2003, Archives of general psychiatry.

[150]  A. Green,et al.  Comorbid schizophrenia and substance abuse. , 2006, The Journal of clinical psychiatry.

[151]  E. Latimer Economic Impacts of Assertive Community Treatment: A Review of the Literature , 1999, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[152]  S. Bartels,et al.  A Pilot Evaluation of the In SHAPE Individualized Health Promotion Intervention for Adults with Mental Illness , 2010, Community Mental Health Journal.

[153]  A. Mann,et al.  Outcome of common mental disorders in Harare, Zimbabwe , 1998, British Journal of Psychiatry.

[154]  E. Laska,et al.  Recovery from psychotic illness: A 15- and 25-year international follow-up study , 2001, British Journal of Psychiatry.

[155]  I. Hickie,et al.  Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions , 2006, The Australian and New Zealand journal of psychiatry.

[156]  K. Minkoff An integrated treatment model for dual diagnosis of psychosis and addiction. , 1989, Hospital & community psychiatry.

[157]  T. Lewander,et al.  Evaluation of the Illness Management and Recovery Scale in schizophrenia and schizoaffective disorder , 2011, Schizophrenia Research.

[158]  Michelle P. Salyers,et al.  A prospective analysis of work in schizophrenia. , 2001, Schizophrenia bulletin.

[159]  G. Patton,et al.  Early intervention in psychotic disorders: faith before facts? , 2009, Psychological Medicine.

[160]  H. Goldman,et al.  Barriers to the care of persons with dual diagnoses: organizational and financing issues. , 1990, Schizophrenia bulletin.

[161]  William A. Anthony,et al.  Recovery from mental illness: The guiding vision of the mental health service system in the 1990s. , 1993 .

[162]  Larry Davidson,et al.  Peer support among persons with severe mental illnesses: a review of evidence and experience , 2012, World psychiatry : official journal of the World Psychiatric Association.

[163]  A. Bellack Scientific and consumer models of recovery in schizophrenia: concordance, contrasts, and implications. , 2005, Schizophrenia bulletin.

[164]  Thomas R Insel,et al.  Translating scientific opportunity into public health impact: a strategic plan for research on mental illness. , 2009, Archives of general psychiatry.

[165]  J. Fiszdon Introduction to Social Cognitive Treatment Approaches for Schizophrenia , 2013 .

[166]  Kim T. Mueser,et al.  Social Skills Training for Schizophrenia: A Step-by-Step Guide , 1997 .

[167]  Lu Liu,et al.  A randomized controlled trial of cognitive behavioral therapy for individuals at clinical high risk of psychosis , 2011, Schizophrenia Research.

[168]  M. Bauer,et al.  What is a "mood stabilizer"? An evidence-based response. , 2004, The American journal of psychiatry.

[169]  A. Jennings On being invisible in the mental health system , 1994, Journal of mental health administration.

[170]  H. Knegtering,et al.  THE EFFECTIVENESS OF PEER SUPPORT GROUPS IN PSYCHOSIS: A RANDOMIZED CONTROLLED TRIAL , 2008, Schizophrenia Research.

[171]  M. Herz Recognizing and preventing relapse in patients with schizophrenia. , 1984, Hospital & community psychiatry.

[172]  S. Mead,et al.  What Recovery Means to Us: Consumers' Perspectives , 2000, Community Mental Health Journal.

[173]  Brigitte Rockstroh,et al.  Endophenotypes in psychopathology research: where do we stand? , 2013, Annual review of clinical psychology.

[174]  M. Goodman,et al.  The relative influences of symptoms, insight, and neurocognition on social adjustment in schizophrenia and schizoaffective disorder. , 1999, The Journal of nervous and mental disease.

[175]  Michael J. Bradley,et al.  The Trauma Recovery Group: A Cognitive-Behavioral Program for Post-Traumatic Stress Disorder in Persons with Severe Mental Illness , 2007, Community Mental Health Journal.

[176]  J. Lieberman,et al.  The early stages of schizophrenia: speculations on pathogenesis, pathophysiology, and therapeutic approaches , 2001, Biological Psychiatry.

[177]  J. Read,et al.  Childhood trauma, psychosis and schizophrenia: a literature review with theoretical and clinical implications , 2005, Acta psychiatrica Scandinavica.

[178]  H. Goldman,et al.  Putting housing first, making housing last: housing policy for persons with severe mental illness. , 2008, The American journal of psychiatry.

[179]  Sonia Johnson,et al.  Schizophrenia and employment - a review. , 2004, Social psychiatry and psychiatric epidemiology.

[180]  P. Deegan Recovery as a journey of the heart. , 1996 .

[181]  A. David,et al.  Psychotic States Arising in Late Life (Late Paraphrenia) , 1995, British Journal of Psychiatry.

[182]  R. Kahn,et al.  School performance as a premorbid marker for schizophrenia: A twin study , 2000, Schizophrenia Research.

[183]  P. McKenna,et al.  Cognitive behavioural therapy for major psychiatric disorder: does it really work? A meta-analytical review of well-controlled trials , 2009, Psychological Medicine.

[184]  A. Yung,et al.  Clinical Staging: A Heuristic and Practical Strategy for New Research and Better Health and Social Outcomes for Psychotic and Related Mood Disorders , 2010, Canadian journal of psychiatry. Revue canadienne de psychiatrie.

[185]  R. Drake,et al.  Assertive Community Treatment for People with Severe Mental Illness , 2001 .

[186]  G. Krarup,et al.  A randomised multicentre trial of integrated versus standard treatment for patients with a first episode of psychotic illness , 2005, BMJ : British Medical Journal.

[187]  J. Zubin,et al.  Vulnerability--a new view of schizophrenia. , 1977, Journal of abnormal psychology.

[188]  P. Gorroochurn,et al.  Randomized trial of critical time intervention to prevent homelessness after hospital discharge. , 2011, Psychiatric services.

[189]  N. Tarrier,et al.  Durability of the effects of cognitive–behavioural therapy in the treatment of chronic schizophrenia: 12-month follow-up , 1999, British Journal of Psychiatry.

[190]  D. Lam,et al.  Family work for schizophrenia : a practical guide , 2002 .

[191]  A. Riecher-Rössler,et al.  Gender aspects in schizophrenia: bridging the border between social and biological psychiatry , 2000, Acta psychiatrica Scandinavica. Supplementum.

[192]  Alan I Green,et al.  Improving the Care of Individuals with Schizophrenia and Substance Use Disorders: Consensus Recommendations , 2005, Journal of psychiatric practice.

[193]  H. Worthington,et al.  Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. , 2007, The Cochrane database of systematic reviews.

[194]  A. Saykin,et al.  Neuroimaging and other biomarkers for Alzheimer's disease: the changing landscape of early detection. , 2013, Annual review of clinical psychology.

[195]  Harriet J. Rosenberg,et al.  A randomized controlled trial of cognitive-behavioral treatment for posttraumatic stress disorder in severe mental illness. , 2008, Journal of consulting and clinical psychology.

[196]  Dennis R. Combs,et al.  The Development of the Social Cognition and Interaction Training Program for Schizophrenia Spectrum Disorders , 2007 .

[197]  R. Drake,et al.  Generalizability of the Individual Placement and Support (IPS) model of supported employment outside the US , 2012, World psychiatry : official journal of the World Psychiatric Association.

[198]  L. Stein,et al.  Assertive Community Treatment of Persons with Severe Mental Illness , 1998 .

[199]  M. Birchwood,et al.  Early intervention in psychosis: the critical‐period hypothesis , 1998, British Journal of Psychiatry.

[200]  K. Mueser,et al.  A meta-analysis of controlled research on social skills training for schizophrenia. , 2008, Journal of consulting and clinical psychology.

[201]  R. Drake,et al.  Models of community care for severe mental illness: a review of research on case management. , 1998, Schizophrenia bulletin.

[202]  P. Solomon,et al.  The efficacy of a consumer case management team: 2-year outcomes of a randomized trial , 2006, The journal of mental health administration.

[203]  D. Velligan,et al.  Effect of a Motivational Intervention on Exercise Behavior in Persons with Schizophrenia Spectrum Disorders , 2011, Community Mental Health Journal.

[204]  P. Deegan Recovery: The lived experience of rehabilitation. , 1988 .

[205]  P. Lysaker,et al.  The prevalence and correlates of trauma-related symptoms in schizophrenia spectrum disorder. , 2008, Comprehensive psychiatry.

[206]  H. Inskip,et al.  Twenty-five year mortality of a community cohort with schizophrenia , 2010, British Journal of Psychiatry.

[207]  I. Falloon,et al.  Family Care of Schizophrenia: A Problem-solving Approach to the Treatment of Mental Illness , 1984 .

[208]  M. Pfammatter,et al.  Efficacy of psychological therapy in schizophrenia: conclusions from meta-analyses. , 2006, Schizophrenia bulletin.

[209]  Harriet J. Rosenberg,et al.  Treatment of Posttraumatic Stress Disorder in Special Populations: A Cognitive Restructuring Program , 2009 .

[210]  C. Wallace,et al.  Teaching psychiatric inpatients to re-enter the community: a brief method of improving the continuity of care. , 1998, Psychiatric services.

[211]  Thomas E. Smith,et al.  Predictors of risk of nonadherence in outpatients with schizophrenia and other psychotic disorders. , 2002, Schizophrenia bulletin.

[212]  Dennis R. Combs,et al.  Modification of affect perception deficits in schizophrenia , 2000, Schizophrenia Research.

[213]  A. Preti,et al.  Randomized-controlled trials in people at ultra high risk of psychosis: A review of treatment effectiveness , 2010, Schizophrenia Research.

[214]  N. Tarrier,et al.  Families of Schizophrenic Patients: Cognitive Behavioural Intervention , 1992 .

[215]  Alexander L. Miller,et al.  Comparing the efficacy of interventions that use environmental supports to improve outcomes in patients with schizophrenia , 2008, Schizophrenia Research.

[216]  B. Happell,et al.  The High Prevalence of Poor Physical Health and Unhealthy Lifestyle Behaviours in Individuals with Severe Mental Illness , 2011, Issues in mental health nursing.

[217]  Michelle P. Salyers,et al.  Cognitive-Behavioral Treatmenzt of PTSD in Severe Mental Illness: Results of a Pilot Study , 2004 .

[218]  Craig W. Colton,et al.  Congruencies in Increased Mortality Rates, Years of Potential Life Lost, and Causes of Death Among Public Mental Health Clients in Eight States , 2006, Preventing chronic disease.

[219]  E. Deci,et al.  Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. , 2000, The American psychologist.

[220]  R. Drake,et al.  A systematic review of psychosocial research on psychosocial interventions for people with co-occurring severe mental and substance use disorders. , 2008, Journal of substance abuse treatment.

[221]  B. Everitt,et al.  Cognitive Behavior Therapy for Schizophrenia: Effect Sizes, Clinical Models, and Methodological Rigor , 2007, Schizophrenia bulletin.

[222]  R. Drake,et al.  Fundamental principles of evidence-based medicine applied to mental health care. , 2003, The Psychiatric clinics of North America.

[223]  L. Schmidt,et al.  The impact of substance use disorders on the course of schizophrenia—A 15-year follow-up study Dual diagnosis over 15 years , 2011, Schizophrenia Research.

[224]  R. Rosenheck,et al.  Outcomes of critical time intervention case management of homeless veterans after psychiatric hospitalization. , 2007, Psychiatric services.

[225]  I. Cormac,et al.  Cognitive behaviour therapy versus other psychosocial treatments for schizophrenia. , 2012, The Cochrane database of systematic reviews.

[226]  S. McGurk,et al.  Cognitive training and supported employment for persons with severe mental illness: one-year results from a randomized controlled trial. , 2005, Schizophrenia bulletin.

[227]  Alexander L. Miller,et al.  The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia. , 2007, Schizophrenia bulletin.

[228]  Michael F. Green,et al.  Cognitive impairment and functional outcome in schizophrenia and bipolar disorder. , 2006, The Journal of clinical psychiatry.

[229]  School Performance as a Premorbid Marker for Schizophrenia: A Twin Study , 2002 .

[230]  J. Marley Return To Community: Building Support Systems for People With Psychiatric Disabilities , 1995 .