Application of Biocatalytic Reductive Amination for the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor
暂无分享,去创建一个
E. Hansen | Rajesh Kumar | S. Sutton | Sebastien Monfette | Daniel W. Widlicka | M. Burns | Holly E Strohmeyer | Jeremy Steflik | S. Duan | Cheryl M. Hayward | Lu Han | K. N. Jones | Ian Hotham | Michele T. Buetti-Weekly | J. Desrosiers | Paul Bowles | Lindsay D. Nicholson | Christopher Morris
[1] Nga M. Do,et al. Biocatalytic reductive amination from discovery to commercial manufacturing applied to abrocitinib JAK1 inhibitor , 2021, Nature Catalysis.
[2] J. Lapek,et al. Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer. , 2021, Journal of medicinal chemistry.
[3] Teresa W. Makowski,et al. A radical chlorodifluoromethylation protocol for late-stage difluoromethylation and its application to an oncology candidate , 2021 .
[4] B. O’Neill,et al. Ketoreductase/Transaminase, One-Pot, Multikilogram Biocatalytic Cascade Reaction , 2021 .
[5] Jason Mustakis,et al. Developing a Multistep Continuous Manufacturing Process for (1R,2R)-2-Amino-1-methylcyclopentan-1-ol , 2020 .
[6] U. Bornscheuer,et al. Biocatalysis: Enzymatic Synthesis for Industrial Applications , 2020, Angewandte Chemie.
[7] A. Bommarius,et al. Recent Advances in ω-Transaminase-Mediated Biocatalysis for the Enantioselective Synthesis of Chiral Amines , 2018, Catalysts.
[8] John M. Woodley,et al. Role of Biocatalysis in Sustainable Chemistry. , 2017, Chemical reviews.
[9] N. Turner,et al. NAD(P)H‐Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application , 2017, Advanced synthesis & catalysis.
[10] Nicholas J Turner,et al. Imine reductases (IREDs). , 2017, Current opinion in chemical biology.
[11] M. Dowsett,et al. Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor-Positive Breast Cancer. , 2016, Cancer research.
[12] S. Buchwald,et al. Regioselective 2-Amination of Polychloropyrimidines. , 2016, Organic letters.
[13] Wolfgang Kroutil,et al. Biocatalytic Imine Reduction and Reductive Amination of Ketones , 2015 .
[14] Jan Streuff,et al. Titanium-catalyzed reductive umpolung reactions with a metal-free terminal reducing agent. , 2015, Chemistry.
[15] H. Kohls,et al. Recent achievements in developing the biocatalytic toolbox for chiral amine synthesis. , 2014, Current opinion in chemical biology.
[16] F. G. Mutti,et al. Asymmetric Preparation of prim-, sec-, and tert-Amines Employing Selected Biocatalysts , 2013, Organic process research & development.
[17] Jan Streuff,et al. Enantioselective titanium(III)-catalyzed reductive cyclization of ketonitriles. , 2012, Angewandte Chemie.
[18] T. Nugent. Chiral amine synthesis : methods, developments and applications , 2010 .
[19] Toyokazu Yoshida,et al. Imine Reductases for Chiral Amine Synthesis , 2017 .
[20] D. Vasić-Rački,et al. Cofactor regeneration at the lab scale. , 2005, Advances in biochemical engineering/biotechnology.