Effects of judgement process on motor evoked potentials in Go/No-go hand movement task

We examined the motor evoked potentials (MEP) of the forearm muscles following transcranial magnetic stimulation after the Go/No-go reaction-time hands movement in ten normal subjects. Facilitation of MEP of the agonistic muscles and suppression of MEP of the antagonistic muscles were recognized during the 'Go' session, while the MEPs of both muscles were markedly suppressed in the 'No-go' session. We considered that this MEP changes reflected the inhibition on the pyramidal tract during the 'No-go' session.

[1]  K. Sasaki,et al.  Suppression of visually initiated hand movement by stimulation of the prefrontal cortex in the monkey , 1989, Brain Research.

[2]  E. Evarts,et al.  Relation of pyramidal tract activity to force exerted during voluntary movement. , 1968, Journal of neurophysiology.

[3]  C. Fromm,et al.  Contrasting properties of pyramidal tract neurons located in the precentral or postcentral areas and of corticorubral neurons in the behaving monkey. , 1983, Advances in neurology.

[4]  C. Marsden,et al.  Transmission in the spinal reciprocal Ia inhibitory pathway preceding willed movements of the human wrist , 1983, Neuroscience Letters.

[5]  R Porter,et al.  Supplementary motor area and premotor area of monkey cerebral cortex: functional organization and activities of single neurons during performance of a learned movement. , 1983, Advances in neurology.

[6]  R. Kakigi,et al.  Reciprocal change of motor‐evoked potentials preceding voluntary movement in humans , 1996, Muscle & nerve.

[7]  Erik Stalberg,et al.  Pre-movement facilitation of motor-evoked potentials in man during transcranial stimulation of the central motor pathways , 1988, Brain Research.

[8]  C. Tomberg,et al.  Prime mover muscle in finger lift or finger flexion reaction times: identification with transcranial magnetic stimulation. , 1991, Electroencephalography and clinical neurophysiology.

[9]  A. Nambu,et al.  No-go activity in the frontal association cortex of human subjects , 1993, Neuroscience Research.

[10]  E. Evarts Pyramidal tract activity associated with a conditioned hand movement in the monkey. , 1966, Journal of neurophysiology.

[11]  Hisae Gemba,et al.  Potential related to no-go reaction of go/no-go hand movement task with color discrimination in human , 1989, Neuroscience Letters.

[12]  Kisou Kubota,et al.  Preparatory activity of monkey pyramidal tract neurons related to quick movement onset during visual tracking performance , 1979, Brain Research.

[13]  J. Desmedt Motor control mechanisms in health and disease , 1983 .

[14]  D. Kernell,et al.  Responses of the pyramidal tract to stimulation of the baboon's motor cortex , 1967, The Journal of physiology.

[15]  A. Barker,et al.  NON-INVASIVE MAGNETIC STIMULATION OF HUMAN MOTOR CORTEX , 1985, The Lancet.

[16]  R. Tanaka,et al.  Reciprocal La inhibition at the onset of voluntary movements in man. , 1974, Brain Research.

[17]  P. Thompson,et al.  Motor cortex stimulation in intact man. 2. Multiple descending volleys. , 1987, Brain : a journal of neurology.

[18]  J. Sanes,et al.  Regulatory role of proprioceptive input in motor control of phasic or maintained voluntary contractions in man. , 1983, Advances in neurology.

[19]  P. Thompson,et al.  Motor cortex stimulation in intact man. 1. General characteristics of EMG responses in different muscles. , 1987, Brain : a journal of neurology.