Mechanisms of Disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis

[1]  Elizabeth W Karlson,et al.  Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. , 2005, American journal of human genetics.

[2]  L. Alfredsson,et al.  Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case–control study , 2005, Arthritis research & therapy.

[3]  S. Cessie,et al.  Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles , 2005, Annals of the rheumatic diseases.

[4]  L. Klareskog,et al.  Longitudinal analysis of citrullinated protein/peptide antibodies (anti-CP) during 5 year follow up in early rheumatoid arthritis: anti-CP status predicts worse disease activity and greater radiological progression , 2005, Annals of the rheumatic diseases.

[5]  Jan Hillert,et al.  MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction , 2005, Nature Genetics.

[6]  L. Klareskog,et al.  Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity , 2005, Arthritis research & therapy.

[7]  L. Bäckdahl Genetic Dissection of Experimental Arthritis in the DA Rat , 2005 .

[8]  Hyon K. Choi Diet and rheumatoid arthritis: red meat and beyond. , 2004, Arthritis and rheumatism.

[9]  A. Silman,et al.  Dietary risk factors for the development of inflammatory polyarthritis: evidence for a role of high level of red meat consumption. , 2004, Arthritis and rheumatism.

[10]  L. Alfredsson,et al.  A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis. , 2004, Arthritis and rheumatism.

[11]  L. Alfredsson,et al.  Silica exposure is associated with increased risk of developing rheumatoid arthritis: results from the Swedish EIRA study , 2004, Annals of the rheumatic diseases.

[12]  G Strandberg,et al.  Anti-CCP antibody test predicts the disease course during 3 years in early rheumatoid arthritis (the Swedish TIRA project) , 2004, Annals of the rheumatic diseases.

[13]  M. Ahlmén,et al.  Prediction of radiological outcome in early rheumatoid arthritis in clinical practice: role of antibodies to citrullinated peptides (anti-CCP) , 2004, Annals of the rheumatic diseases.

[14]  Steven J. Schrodi,et al.  A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. , 2004, American journal of human genetics.

[15]  D. Symmons,et al.  The role of diet in susceptibility to rheumatoid arthritis: a systematic review. , 2004, The Journal of rheumatology.

[16]  E. Vossenaar,et al.  Citrullinated proteins: sparks that may ignite the fire in rheumatoid arthritis , 2004, Arthritis research & therapy.

[17]  F. Breedveld,et al.  Autoantibodies to cyclic citrullinated peptides predict progression to rheumatoid arthritis in patients with undifferentiated arthritis: a prospective cohort study. , 2004, Arthritis and rheumatism.

[18]  O. Axelson,et al.  Occupations and exposures in the work environment as determinants for rheumatoid arthritis , 2004, Occupational and Environmental Medicine.

[19]  B. Dijkmans,et al.  Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors. , 2004, Arthritis and rheumatism.

[20]  M. Feldmann,et al.  The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis. , 2004, Best practice & research. Clinical rheumatology.

[21]  K. Aho,et al.  Risk factors for rheumatoid arthritis , 2004, Annals of medicine.

[22]  Kutty Selva Nandakumar,et al.  Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. , 2003, The American journal of pathology.

[23]  Göran Hallmans,et al.  Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. , 2003, Arthritis and rheumatism.

[24]  R. Holmdahl Dissection of the genetic complexity of arthritis using animal models. , 2003, Journal of autoimmunity.

[25]  L. Alfredsson,et al.  Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases , 2003, Annals of the rheumatic diseases.

[26]  A. Kang,et al.  Immunopathogenesis of Collagen Arthritis , 2003, Springer Seminars in Immunopathology.

[27]  A. Sette,et al.  Cutting Edge: The Conversion of Arginine to Citrulline Allows for a High-Affinity Peptide Interaction with the Rheumatoid Arthritis-Associated HLA-DRB1*0401 MHC Class II Molecule1 , 2003, The Journal of Immunology.

[28]  W. van Eden,et al.  Immune regulation in adjuvant-induced arthritis: possible implications for innovative therapeutic strategies in arthritis. , 2003, Arthritis and rheumatism.

[29]  Wendy Thomson,et al.  Relationship among the HLA-DRB1 shared epitope, smoking, and rheumatoid factor production in rheumatoid arthritis. , 2002, Arthritis and rheumatism.

[30]  E. Remmers,et al.  Modulation of multiple experimental arthritis models by collagen-induced arthritis quantitative trait loci isolated in congenic rat lines: different effects of non-major histocompatibility complex quantitative trait loci in males and females. , 2002, Arthritis and rheumatism.

[31]  P. Lipsky,et al.  Criteria for early rheumatoid arthritis: from Bayes' law revisited to new thoughts on pathogenesis. , 2002, Arthritis and rheumatism.

[32]  C. Benoist,et al.  Arthritogenic Monoclonal Antibodies from K/BxN Mice , 2002, The Journal of experimental medicine.

[33]  G. Cooper,et al.  Occupational exposures and autoimmune diseases. , 2002, International immunopharmacology.

[34]  R. Holmdahl,et al.  Arthritis induced in rats with non‐immunogenic adjuvants as models for rheumatoid arthritis , 2001, Immunological reviews.

[35]  A. Silman,et al.  High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis. , 2001, Human molecular genetics.

[36]  W. Grant The role of meat in the expression of rheumatoid arthritis , 2000, British Journal of Nutrition.

[37]  D. Symmons,et al.  Early inflammatory polyarthritis: results from the norfolk arthritis register with a review of the literature. I. Risk factors for the development of inflammatory polyarthritis and rheumatoid arthritis. , 2000, Rheumatology.

[38]  A. Reunanen,et al.  Coffee consumption, rheumatoid factor, and the risk of rheumatoid arthritis , 2000, Annals of the rheumatic diseases.

[39]  H. Mcdevitt,et al.  Rheumatoid arthritis and its animal models: the role of TNF-alpha and the possible absence of specific immune reactions. , 1999, Current opinion in immunology.

[40]  J. Lorentzen,et al.  Identification of Arthritogenic Adjuvants of Self and Foreign Origin , 1999, Scandinavian journal of immunology.

[41]  A. Silman,et al.  Cigarette smoking increases the risk of rheumatoid arthritis. Results from a nationwide study of disease-discordant twins. , 1996, Arthritis and rheumatism.

[42]  L. Klareskog,et al.  Adjuvant oils induce arthritis in the DA rat. I. Characterization of the disease and evidence for an immunological involvement , 1991, Journal of Autoimmunity.

[43]  M. Liang,et al.  The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. , 1988, Arthritis and rheumatism.

[44]  P. Gregersen,et al.  The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. , 1987, Arthritis and rheumatism.

[45]  M. Klockars,et al.  Silica exposure and rheumatoid arthritis: a follow up study of granite workers 1940-81. , 1987, British medical journal.

[46]  C. Pearson,et al.  Studies of arthritis and other lesions induced in rats by injection of mycobacterial adjuvant. II. Evidence that the disease is a disseminated immunologic response to exogenous antigen. , 1960, Journal of immunology.

[47]  L. Alfredsson,et al.  A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination. , 2006, Arthritis and rheumatism.

[48]  L. Klareskog,et al.  Oligodeoxynucleotides containing CpG motifs can induce T cell-dependent arthritis in rats. , 2004, Arthritis and rheumatism.

[49]  A S Rigby,et al.  Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. , 2000, Arthritis and rheumatism.