MC50 is the first cyclotron installed at Korea Institute of Radiological and Medical Sciences, Korea Atomic Energy Research Institute. It has been utilized for basic medical researches and production of radioisotopes in addition to treatment of cancer patients since 1986. Additionally, MC50 has contributed to many nuclear sciences researches, such as SER test for semiconductor chipsets, development of variable species by ion beam irradiation, and so on. Recently, we have been running another cyclotron, which is named KIRAMS-30 and only for production of radioisotopes. Therefore, MC50 has become placed more weight on the nuclear sciences researches. It is available to support some researches which use proton, deuteron, He-3, and He-4 beam about 18 » 50MeV.