Sarcoidosis withrenal involvement

Summary Nineofninety patients withsarcoidosis werefound to havesignificant renal impairment. Epithelioid granulomatawerepresent infive ofeight patients whohad renal biopsies andglomerular lesions werepresent in six.Therewasclosecorrelation between hypercalcaemia, hyperuricaemia, nephrocalcinosis and creatinine clearance. Inonepatient, renal sarcoidosis complicated membrano-proliferative glomerulonephritis andonepatient diedinend-stage renal disease.