Newborns of obese parents have altered DNA methylation patterns at imprinted genes

[1]  R. Martorell,et al.  Malnutrition in early life and adult mental health: evidence from a natural experiment. , 2013, Social science & medicine.

[2]  Qiu-Xia Liang,et al.  Maternal Diabetes Causes Alterations of DNA Methylation Statuses of Some Imprinted Genes in Murine Oocytes1 , 2013, Biology of reproduction.

[3]  E. Iversen,et al.  Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring , 2013, International Journal of Obesity.

[4]  T. Haaf,et al.  Metabolic Programming of MEST DNA Methylation by Intrauterine Exposure to Gestational Diabetes Mellitus , 2013, Diabetes.

[5]  T. Haaf,et al.  Epigenetic disturbances in in vitro cultured gametes and embryos: implications for human assisted reproduction. , 2013, Fertility and sterility.

[6]  S. Murphy,et al.  Associations between Methylation of Paternally Expressed Gene 3 (PEG3), Cervical Intraepithelial Neoplasia and Invasive Cervical Cancer , 2013, PloS one.

[7]  S. Murphy,et al.  Paternal obesity is associated with IGF2 hypomethylation in newborns: results from a Newborn Epigenetics Study (NEST) cohort , 2013, BMC Medicine.

[8]  Cong Sun,et al.  Effects of early-life environment and epigenetics on cardiovascular disease risk in children: highlighting the role of twin studies , 2013, Pediatric Research.

[9]  S. Murphy,et al.  Differentially Methylated Regions of Imprinted Genes in Prenatal, Perinatal and Postnatal Human Tissues , 2012, PloS one.

[10]  Paula Krakowiak,et al.  Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders , 2012, Pediatrics.

[11]  E. Iversen,et al.  Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke. , 2012, Gene.

[12]  M. Forman,et al.  The effects of depression and use of antidepressive medicines during pregnancy on the methylation status of the IGF2 imprinted control regions in the offspring , 2011, Clinical Epigenetics.

[13]  J. Berg,et al.  Imprinted Genes That Regulate Early Mammalian Growth Are Coexpressed in Somatic Stem Cells , 2011, PloS one.

[14]  E. Hatzimichael,et al.  MEG3 imprinted gene contribution in tumorigenesis , 2011, International journal of cancer.

[15]  C. Rosenfeld,et al.  Metabolic imprinting by prenatal, perinatal, and postnatal overnutrition: a review. , 2011, Seminars in reproductive medicine.

[16]  Julie Herbstman,et al.  Prenatal environmental exposures, epigenetics, and disease. , 2011, Reproductive Toxicology.

[17]  S. Murphy,et al.  Folic acid supplementation before and during pregnancy in the Newborn Epigenetics STudy (NEST) , 2011, BMC public health.

[18]  Zhiping Weng,et al.  Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals , 2010, Cell.

[19]  Margaret J. Morris,et al.  Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring , 2010, Nature.

[20]  R. Martorell,et al.  Early life exposure to the 1959-1961 Chinese famine has long-term health consequences. , 2010, The Journal of nutrition.

[21]  R. Reynolds,et al.  Impact of maternal obesity on offspring obesity and cardiometabolic disease risk. , 2010, Reproduction.

[22]  P. J. Larsen,et al.  The Imprinted Gene Neuronatin Is Regulated by Metabolic Status and Associated With Obesity , 2010, Obesity.

[23]  E. Steegers,et al.  Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child , 2009, PloS one.

[24]  Laurent Journot,et al.  H19 acts as a trans regulator of the imprinted gene network controlling growth in mice , 2009, Development.

[25]  J. Romijn,et al.  Lipid profiles in middle-aged men and women after famine exposure during gestation: the Dutch Hunger Winter Families Study. , 2009, The American journal of clinical nutrition.

[26]  M. Oshimura,et al.  Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma , 2009, Proceedings of the Japan Academy. Series B, Physical and biological sciences.

[27]  A. Feinberg,et al.  Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene , 2009, Epigenetics.

[28]  J. Rankin,et al.  Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis. , 2009, JAMA.

[29]  Hein Putter,et al.  Persistent epigenetic differences associated with prenatal exposure to famine in humans , 2008, Proceedings of the National Academy of Sciences.

[30]  B. Crespi,et al.  Genomic imprinting in the development and evolution of psychotic spectrum conditions , 2008, Biological reviews of the Cambridge Philosophical Society.

[31]  C. Stratakis,et al.  Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas. , 2008, The Journal of clinical endocrinology and metabolism.

[32]  J. Baron,et al.  An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[33]  R. D'Agostino,et al.  Parental obesity and offspring serum alanine and aspartate aminotransferase levels: the Framingham heart study. , 2008, Gastroenterology.

[34]  M. Järvelin,et al.  Maternal adiposity prior to pregnancy is associated with ADHD symptoms in offspring: evidence from three prospective pregnancy cohorts , 2008, International Journal of Obesity.

[35]  R. Jirtle,et al.  Environmental epigenomics and disease susceptibility , 2007, Nature Reviews Genetics.

[36]  P. Bossuyt,et al.  A possible link between prenatal exposure to famine and breast cancer: A preliminary study , 2006, American journal of human biology : the official journal of the Human Biology Council.

[37]  Dany Severac,et al.  Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth. , 2006, Developmental cell.

[38]  Clive Osmond,et al.  Early onset of coronary artery disease after prenatal exposure to the Dutch famine. , 2006, The American journal of clinical nutrition.

[39]  M. Suzuki,et al.  Parental obesity and overweight affect the body‐fat accumulation in the offspring: the possible effect of a high‐fat diet through epigenetic inheritance , 2006, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[40]  A. Berchuck,et al.  Frequent IGF2/H19 Domain Epigenetic Alterations and Elevated IGF2 Expression in Epithelial Ovarian Cancer , 2006, Molecular Cancer Research.

[41]  W. Alvord,et al.  Preconceptional fasting of fathers alters serum glucose in offspring of mice. , 2006, Nutrition.

[42]  J. Molès,et al.  The Candidate Tumor Suppressor Gene ZAC Is Involved in Keratinocyte Differentiation and Its Expression Is Lost in Basal Cell Carcinomas , 2005, Molecular Cancer Research.

[43]  Jing Zhao,et al.  Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors. , 2005, The Journal of clinical endocrinology and metabolism.

[44]  T. Hamilton,et al.  Altered expression and loss of heterozygosity of the LOT1 gene in ovarian cancer. , 2004, Gynecologic oncology.

[45]  K. Friedrich,et al.  Loss of expression of ZAC/LOT1 in squamous cell carcinomas of head and neck , 2004, Head & neck.

[46]  A. Feinberg,et al.  Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition. , 2004, Gastroenterology.

[47]  A. Feinberg,et al.  Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. , 2002, Cancer research.

[48]  S. Edvinsson,et al.  Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period , 2002, European Journal of Human Genetics.

[49]  D. Barker,et al.  The thrifty phenotype hypothesis. , 2001, British medical bulletin.

[50]  M. Goran,et al.  Paternal body fat is a longitudinal predictor of changes in body fat in premenarcheal girls. , 2000, The American journal of clinical nutrition.

[51]  A. Reeve,et al.  Relaxation of IGF2 imprinting in Wilms tumours associated with specific changes in IGF2 methylation , 1999, Oncogene.

[52]  J. Bockaert,et al.  Loss of expression of the candidate tumor suppressor gene ZAC in breast cancer cell lines and primary tumors , 1999, Oncogene.

[53]  C. Osmond,et al.  Blood pressure in adults after prenatal exposure to famine. , 1999, Journal of hypertension.

[54]  M. Azim Surani,et al.  Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest , 1998, Nature Genetics.

[55]  D. Barker,et al.  Intrauterine programming of coronary heart disease and stroke , 1997, Acta paediatrica (Oslo, Norway : 1992). Supplement.

[56]  A. Feinberg,et al.  Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour , 1994, Nature Genetics.

[57]  M. Susser,et al.  Obesity in young men after famine exposure in utero and early infancy. , 1976, The New England journal of medicine.

[58]  J. Baron,et al.  A set of imprinted genes required for normal body growth also promotes growth of rhabdomyosarcoma cells , 2012, Pediatric Research.

[59]  Y. Kamei,et al.  Mest/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size. , 2005, American journal of physiology. Endocrinology and metabolism.

[60]  R. Waterland,et al.  Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases. , 2004, Nutrition.

[61]  Doha Kim Loss of Imprinting of Insulin Growth Factor II Gene: A Potential Heritable Biomarker for Colon Neoplasia Predisposition. , 2004 .

[62]  D. Malaspina,et al.  Paternal factors and schizophrenia risk: de novo mutations and imprinting. , 2001, Schizophrenia bulletin.