Rational optimization of tumor epitopes using in silico analysis‐assisted substitution of TCR contact residues
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Bing Ni | Li Wang | Li Wang | B. Ni | Yuzhang Wu | Zhao Yang | Xiao-lan Fu | Xiaoyun Shang | Wei Niu | Gang Meng | Zhihua Lin | Xiaoling Chen | Gang Meng | Yuzhang Wu | Xiaoyun Shang | Wei Niu | Xiaolan Fu | Zhihua Lin | Zhao Yang | Xiaolin Chen
[1] Luhua Lai,et al. A combinatorial score to distinguish biological and nonbiological protein–protein interfaces , 2006, Proteins.
[2] Partho Ghosh,et al. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2 , 1996, Nature.
[3] K. Parker,et al. HLA-A1 and HLA-A3 T cell epitopes derived from influenza virus proteins predicted from peptide binding motifs. , 1993, Journal of immunology.
[4] Wei Zhou,et al. H-2 Kd-Restricted Hepatitis B Virus-Derived Epitope Whose Specific CD8+ T Lymphocytes Can Produce Gamma Interferon without Cytotoxicity , 2005, Journal of Virology.
[5] B M Baker,et al. Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. , 1999, Immunity.
[6] L. Edelstein-Keshet,et al. Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide , 2005, Nature Medicine.
[7] Andrew Sewell,et al. Structural and kinetic basis for heightened immunogenicity of T cell vaccines , 2005, The Journal of experimental medicine.
[8] V. Cerundolo,et al. Identification of NY-ESO-1 Peptide Analogues Capable of Improved Stimulation of Tumor-Reactive CTL1 , 2000, The Journal of Immunology.
[9] K. Garcia,et al. A functional hot spot for antigen recognition in a superagonist TCR/MHC complex. , 2000, Immunity.
[10] S. Perez,et al. Vaccination with human HER-2/neu (435-443) CTL peptide induces effective antitumor immunity against HER-2/neu-expressing tumor cells in vivo. , 2006, Cancer research.
[11] T. Beddoe,et al. Functional and Structural Characteristics of NY-ESO-1-related HLA A2-restricted Epitopes and the Design of a Novel Immunogenic Analogue* , 2004, Journal of Biological Chemistry.
[12] D. Speiser,et al. Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens. , 2006, Cancer research.
[13] H. Grey,et al. Termination of peripheral tolerance to a T cell epitope by heteroclitic antigen analogues. , 1998, Journal of immunology.
[14] D. Valmori,et al. Distinct Structural TCR Repertoires in Naturally Occurring Versus Vaccine-Induced CD8+ T-Cell Responses to the Tumor-Specific Antigen NY-ESO-1 , 2005, Journal of immunotherapy.
[15] J. Sacchettini,et al. A Structural Difference Limited to One Residue of the Antigenic Peptide Can Profoundly Alter the Biological Outcome of the TCR-Peptide/MHC Class I Interaction1 , 2001, The Journal of Immunology.
[16] F. Lemonnier,et al. A general strategy to enhance immunogenicity of low‐affinity HLA‐A2.1‐associated peptides: implication in the identification of cryptic tumor epitopes , 2000, European journal of immunology.
[17] J. Sidney,et al. Improved Immunogenicity of an Immunodominant Epitope of the Her-2/neu Protooncogene by Alterations of MHC Contact Residues1 , 2004, The Journal of Immunology.
[18] David E. Kim,et al. Computational Alanine Scanning of Protein-Protein Interfaces , 2004, Science's STKE.
[19] E. Jaffee,et al. Enhanced antigen-specific antitumor immunity with altered peptide ligands that stabilize the MHC-peptide-TCR complex. , 2000, Immunity.
[20] Darren R Flower,et al. Coupling In Silico and In Vitro Analysis of Peptide-MHC Binding: A Bioinformatic Approach Enabling Prediction of Superbinding Peptides and Anchorless Epitopes , 2004, The Journal of Immunology.
[21] H. Grey,et al. The Stimulation of Low-Affinity, Nontolerized Clones by Heteroclitic Antigen Analogues Causes the Breaking of Tolerance Established to an Immunodominant T Cell Epitope , 1999, The Journal of experimental medicine.
[22] Fenglou Mao,et al. Potential of mean force for protein–protein interaction studies , 2002, Proteins.
[23] B. Kavanagh,et al. Distinct CD8+ T Cell Repertoires Primed with Agonist and Native Peptides Derived from a Tumor-Associated Antigen1 , 2008, The Journal of Immunology.
[24] John Sidney,et al. Structural Features of Peptide Analogs of Human Histocompatibility Leukocyte Antigen Class I Epitopes That Are More Potent and Immunogenic than Wild-Type Peptide , 2001, The Journal of experimental medicine.
[25] B. Ni,et al. An altered peptide ligand for naïve cytotoxic T lymphocyte epitope of TRP-2(180–188) enhanced immunogenicity , 2006, Cancer Immunology, Immunotherapy.
[26] J. Cormier,et al. Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides. , 1996, Cancer research.
[27] Tak H. Lee,et al. Cytokine Coexpression During Human Th1/Th2 Cell Differentiation: Direct Evidence for Coordinated Expression of Th2 Cytokines1 , 2002, The Journal of Immunology.
[28] Z. Ruan,et al. Identification of a new HLA-A*0201-restricted cytotoxic T lymphocyte epitope from CML28 , 2006, Cancer Immunology, Immunotherapy.
[29] S. Steinberg,et al. Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression. , 1999, Journal of immunology.
[30] D. Gilden,et al. Rapid and efficient identification of epitopes/mimotopes from random peptide libraries. , 2006, Journal of immunological methods.
[31] Peter V Coveney,et al. Peptide recognition by the T cell receptor: comparison of binding free energies from thermodynamic integration, Poisson–Boltzmann and linear interaction energy approximations , 2005, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.
[32] Shunzhou Wan,et al. Large‐scale molecular dynamics simulations of HLA‐A*0201 complexed with a tumor‐specific antigenic peptide: Can the α3 and β2m domains be neglected? , 2004, J. Comput. Chem..
[33] C. Pinilla,et al. Identification of Cross-Reactive Peptides Using Combinatorial Libraries Circumvents Tolerance against Her-2/neu-Immunodominant Epitope1 , 2006, The Journal of Immunology.
[34] Olivier Michielin,et al. Binding free energy differences in a TCR-peptide-MHC complex induced by a peptide mutation: a simulation analysis. , 2002, Journal of molecular biology.
[35] Wenda Gao,et al. Induction of specific human primary immune responses to a Semliki Forest virus–based tumor vaccine in a Trimera mouse model , 2005, Cancer Immunology, Immunotherapy.
[36] D. Baker,et al. A simple physical model for binding energy hot spots in protein–protein complexes , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[37] Yao-Tseng Chen,et al. A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening. , 1997, Proceedings of the National Academy of Sciences of the United States of America.