Involvement of Pax6 and Otx2 in the forebrain-specific regulation of the vertebrate homeobox gene ANF/Hesx1.

[1]  S. Chapman,et al.  Anterior identity is established in chick epiblast by hypoblast and anterior definitive endoderm , 2003, Development.

[2]  L. Williams-Simons,et al.  A novel inducible element, activated by contact with Rathke's pouch, is present in the regulatory region of the Rpx/Hesx1 homeobox gene. , 2003, Developmental biology.

[3]  P. Gruss,et al.  Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6 , 2003, Development.

[4]  P. Gruss,et al.  Pax6 is required for establishing naso-temporal and dorsal characteristics of the optic vesicle. , 2002, Development.

[5]  J. Samarut,et al.  Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[6]  A. Zaraisky,et al.  Characterization of cis-regulatory elements of the homeobox gene Xanf-1. , 2002, Gene.

[7]  Yukinori Endo,et al.  Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development. , 2002, Development.

[8]  B. Thisse,et al.  A zebrafish nanos-related gene is essential for the development of primordial germ cells. , 2001, Genes & development.

[9]  E. Boncinelli,et al.  Downstream of Otx2, or how to get a head. , 2001, Trends in genetics : TIG.

[10]  P. Gruss,et al.  Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium. , 2001, Development.

[11]  F. Guillemot,et al.  Pax6 Is Required for the Multipotent State of Retinal Progenitor Cells , 2001, Cell.

[12]  A. Streit,et al.  Combined whole-mount in situ hybridization and immunohistochemistry in avian embryos. , 2001, Methods.

[13]  S. Chapman,et al.  Improved method for chick whole‐embryo culture using a filter paper carrier , 2001, Developmental dynamics : an official publication of the American Association of Anatomists.

[14]  R. Beddington,et al.  The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation. , 2000, Developmental biology.

[15]  H. Nakamura,et al.  Pax6 defines the di-mesencephalic boundary by repressing En1 and Pax2. , 2000, Development.

[16]  C. Barnstable,et al.  The subcellular localization of Otx2 is cell-type specific and developmentally regulated in the mouse retina. , 2000, Brain research. Molecular brain research.

[17]  G. Ermakova,et al.  The homeobox gene, Xanf-1, can control both neural differentiation and patterning in the presumptive anterior neurectoderm of the Xenopus laevis embryo. , 1999, Development.

[18]  A. Dierich,et al.  Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain. , 1999, Development.

[19]  M. Kessel,et al.  Head-organizing activities of endodermal tissues in vertebrates. , 1999, Cellular and molecular biology.

[20]  P. Briata,et al.  Binding properties of the human homeodomain protein OTX2 to a DNA target sequence , 1999, FEBS letters.

[21]  C. Viebahn,et al.  Head induction in the chick by primitive endoderm of mammalian, but not avian origin. , 1999, Development.

[22]  A. Cvekl,et al.  Dual Roles for Pax-6: a Transcriptional Repressor of Lens Fiber Cell-Specific β-Crystallin Genes , 1998, Molecular and Cellular Biology.

[23]  J. Martinez-Barbera,et al.  Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse , 1998, Nature Genetics.

[24]  G. Ermakova,et al.  Anf: a novel class of vertebrate homeobox genes expressed at the anterior end of the main embryonic axis. , 1997, Gene.

[25]  A. Kawakami,et al.  Distributions of PAX6 and PAX7 proteins suggest their involvement in both early and late phases of chick brain development , 1997, Mechanisms of Development.

[26]  T. Jessell,et al.  Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling , 1997, Cell.

[27]  P. Gruss,et al.  Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas , 1997, Nature.

[28]  R. Beddington,et al.  Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo , 1996, Current Biology.

[29]  P. Brûlet,et al.  Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. , 1995, Development.

[30]  C. Kimmel,et al.  Stages of embryonic development of the zebrafish , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[31]  P. Rathjen,et al.  Sequence, Genomic Organization, and Expression of the Novel Homeobox Gene Hesx1(*) , 1995, The Journal of Biological Chemistry.

[32]  M. Gulisano,et al.  c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo , 1995, Mechanisms of Development.

[33]  J. Thompson,et al.  CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. , 1994, Nucleic acids research.

[34]  J A Epstein,et al.  Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing. , 1994, Genes & development.

[35]  D. Pasko,et al.  Pax-6 is first expressed in a region of ectoderm anterior to the early neural plate: implications for stepwise determination of the lens. , 1994, Developmental biology.

[36]  E. Oxtoby,et al.  Cloning of the zebrafish krox-20 gene (krx-20) and its expression during hindbrain development. , 1993, Nucleic acids research.

[37]  P. Gruss,et al.  Pax-6, a murine paired box gene, is expressed in the developing CNS. , 1991, Development.

[38]  M. Nakafuku,et al.  Early subdivisions in the neural plate define distinct competence for inductive signals. , 2002, Development.

[39]  D. Dunger,et al.  Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia. , 2001, Human molecular genetics.

[40]  Xin Chen,et al.  TRANSFAC: an integrated system for gene expression regulation , 2000, Nucleic Acids Res..

[41]  T. Jessell,et al.  Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube. , 1997, Cold Spring Harbor symposia on quantitative biology.

[42]  S. Mackem,et al.  Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo. , 1996, Development.

[43]  V. Hamburger,et al.  A series of normal stages in the development of the chick embryo. 1951. , 2012, Developmental dynamics : an official publication of the American Association of Anatomists.