Pathway analysis of seven common diseases assessed by genome-wide association.

[1]  W. Bodmer,et al.  Common and rare variants in multifactorial susceptibility to common diseases , 2008, Nature Genetics.

[2]  J. Bobes,et al.  The prevalence of metabolic syndrome in patients with bipolar disorder. , 2008, Journal of affective disorders.

[3]  Mi Young Lee,et al.  Dual knockdown of p65 and p50 subunits of NF-kappaB by siRNA inhibits the induction of inflammatory cytokines and significantly enhance apoptosis in human primary synoviocytes treated with tumor necrosis factor-alpha , 2008, Molecular Biology Reports.

[4]  Christian Hölscher,et al.  Common pathological processes in Alzheimer disease and type 2 diabetes: A review , 2007, Brain Research Reviews.

[5]  Kai Wang,et al.  Pathway-based approaches for analysis of genomewide association studies. , 2007, American journal of human genetics.

[6]  R. Xavier,et al.  AKAP13, a RhoA GTPase-specific Guanine Exchange Factor, Is a Novel Regulator of TLR2 Signaling* , 2007, Journal of Biological Chemistry.

[7]  S. Camper,et al.  TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. , 2007, Developmental biology.

[8]  V. Andrés,et al.  Telomere dysfunction in hypertension , 2007, Journal of hypertension.

[9]  Jianfeng Xu,et al.  Assembly of Inflammation-Related Genes for Pathway-Focused Genetic Analysis , 2007, PloS one.

[10]  C. Thaller,et al.  The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors , 2007, Proceedings of the National Academy of Sciences.

[11]  G. Firestein,et al.  Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis. , 2007, The Journal of rheumatology.

[12]  Pauline C Ng,et al.  Power to Detect Risk Alleles Using Genome-Wide Tag SNP Panels , 2007, PLoS genetics.

[13]  T. Yang,et al.  Microsomal prostaglandin E synthase-1 and blood pressure regulation. , 2007, Kidney international.

[14]  Pimonrat Ketsawatsomkron,et al.  Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation. , 2007, American journal of physiology. Heart and circulatory physiology.

[15]  R. Pope,et al.  Increased macrophage activation mediated through toll-like receptors in rheumatoid arthritis. , 2007, Arthritis and rheumatism.

[16]  Lewis C. Cantley,et al.  AKT/PKB Signaling: Navigating Downstream , 2007, Cell.

[17]  E. Keystone,et al.  Distinctive gene expression signatures in rheumatoid arthritis synovial tissue fibroblast cells: correlates with disease activity , 2007, Genes and Immunity.

[18]  Simon C. Potter,et al.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.

[19]  P. Jose,et al.  The dopaminergic system in hypertension. , 2007, Clinical science.

[20]  E Crivellato,et al.  Macrophages in rheumatoid arthritis. , 2007, Histology and histopathology.

[21]  B. Ford,et al.  Neuregulin-1 Attenuates Neointimal Formation following Vascular Injury and Inhibits the Proliferation of Vascular Smooth Muscle Cells , 2007, Journal of Vascular Research.

[22]  J. Goodrich,et al.  Characterization of the sequence and architectural constraints of the regulatory and core regions of the human interleukin-2 promoter. , 2007, Molecular immunology.

[23]  Y. Shoenfeld,et al.  Vascular Endothelial Growth Factor (VEGF) in Autoimmune Diseases , 2007, Journal of Clinical Immunology.

[24]  M. Raizada,et al.  Lack of Macrophage Migration Inhibitory Factor Regulation Is Linked to the Increased Chronotropic Action of Angiotensin II in SHR Neurons , 2007, Hypertension.

[25]  T. Teramoto,et al.  Plasmalogens in human serum positively correlate with high- density lipoprotein and decrease with aging. , 2007, Journal of atherosclerosis and thrombosis.

[26]  Ji Luo,et al.  The p85α Regulatory Subunit of Phosphoinositide 3-Kinase Potentiates c-Jun N-Terminal Kinase-Mediated Insulin Resistance , 2007 .

[27]  F. Clerget-Darpoux,et al.  Strategy for Detecting Susceptibility Genes with Weak or No Marginal Effect , 2007, Human Heredity.

[28]  W. Ferrell,et al.  Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis. , 2007, Arthritis and rheumatism.

[29]  W. Elliott.  Drug Interactions and Drugs That Affect Blood Pressure , 2006, Journal of clinical hypertension.

[30]  J. Galmiche,et al.  Altered lipid, apolipoprotein, and lipoprotein profiles in inflammatory bowel disease: consequences on the cholesterol efflux capacity of serum using Fu5AH cell system. , 2006, Metabolism: clinical and experimental.

[31]  A. Hofman,et al.  A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study. , 2006, Journal of the American College of Cardiology.

[32]  M. Dubé,et al.  Common Genetic Vulnerability to Depressive Symptoms and Coronary Artery Disease: A Review and Development of Candidate Genes Related to Inflammation and Serotonin , 2006, Psychosomatic medicine.

[33]  S. Narumiya,et al.  Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis , 2006, The Journal of experimental medicine.

[34]  M. Wenk.  The emerging field of lipidomics , 2005, Nature Reviews Drug Discovery.

[35]  R. T. Smith,et al.  A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[36]  Jan Hillert,et al.  MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction , 2005, Nature Genetics.

[37]  E. Boerwinkle,et al.  The β2-adrenergic receptor Arg16-gly polymorphism and interactions involving β2- and β3-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: The Bogalusa Heart Study , 2004 .

[38]  A. Rao,et al.  Activation and deactivation of gene expression by Ca2+/calcineurin-NFAT-mediated signaling. , 2004, Molecules and cells.

[39]  G. Owens,et al.  Molecular regulation of vascular smooth muscle cell differentiation in development and disease. , 2004, Physiological reviews.

[40]  D. Kemp,et al.  Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells. , 2004, Endocrinology.

[41]  Sudhir Kumar,et al.  MEGA3: Integrated software for Molecular Evolutionary Genetics Analysis and sequence alignment , 2004, Briefings Bioinform..

[42]  W. A. Yeudall,et al.  Accelerated Cell Cycle Progression in Osteoblasts Overexpressing the c-fos Proto-oncogene , 2004, Journal of Biological Chemistry.

[43]  S. Faraone,et al.  An overview of the genetics of psychotic mood disorders. , 2004, Journal of psychiatric research.

[44]  E. Boerwinkle,et al.  The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study. , 2004, Metabolism: clinical and experimental.

[45]  S. Grundy.  Inflammation, hypertension, and the metabolic syndrome. , 2003, JAMA.

[46]  E. Topol,et al.  Mutation of MEF2A in an Inherited Disorder with Features of Coronary Artery Disease , 2003, Science.

[47]  G. Lip,et al.  Angiogenesis, thrombogenesis, endothelial dysfunction and angiographic severity of coronary artery disease , 2003, Heart.

[48]  A. Golik,et al.  Serum magnesium aberrations in furosemide (frusemide) treated patients with congestive heart failure: pathophysiological correlates and prognostic evaluation , 2003, Heart.

[49]  R. K Srivastava,et al.  Differential roles of RelA (p65) and c-Rel subunits of nuclear factor kappa B in tumor necrosis factor-related apoptosis-inducing ligand signaling. , 2003, Cancer research.

[50]  P. D. Rijk,et al.  A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorder , 2002, Molecular Psychiatry.

[51]  Ernesto L. Schiffrin,et al.  Vascular Remodeling in Hypertension: Roles of Apoptosis, Inflammation, and Fibrosis , 2001, Hypertension.

[52]  L Shapiro,et al.  G-Protein Signaling Through Tubby Proteins , 2001, Science.

[53]  J. Kelsoe,et al.  Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach. , 2000, Physiological genomics.

[54]  L. Tartaglia,et al.  Tyrosine Phosphorylation of Tub and Its Association with Src Homology 2 Domain-containing Proteins Implicate Tub in Intracellular Signaling by Insulin* , 1999, Journal of Biological Chemistry.

[55]  J. Nordrehaug,et al.  Serotonin is associated with coronary artery disease and cardiac events. , 1999, Circulation.

[56]  R. Bucala,et al.  Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids. , 1999, Arthritis and rheumatism.

[57]  A. Manning,et al.  AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis. , 1998, Autoimmunity.

[58]  R. Maki,et al.  Stimulation of macrophages by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU.1 via activation of casein kinase II. , 1997, Journal of immunology.

[59]  R. Scharfmann,et al.  Expression of Neuronal Traits in Pancreatic Beta Cells , 1997, The Journal of Biological Chemistry.

[60]  C. Ebeling,et al.  Identification and Characterization of the Mouse Obesity Gene tubby: A Member of a Novel Gene Family , 1996, Cell.

[61]  M. Burdick,et al.  Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis. , 1992, The Journal of clinical investigation.

[62]  P. Gregersen,et al.  The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. , 1987, Arthritis and rheumatism.

[63]  S. Krane,et al.  PROSTAGLANDINS AND THEIR REGULATION IN RHEUMATOID INFLAMMATION * , 1979, Annals of the New York Academy of Sciences.